Database Searching
Entrez (NCBI) Query GenBank database (NCBI) Sequence retrieval system (SRS, EBI) PDB search Swissprot (ExPaSy)| BLAST (NCBI) Fasta (EBI) The PredictProtein server
Motif Identification
InterPro (EBI) Prosite (ExPaSy) Pfam (The Sanger Centre) Prodom (INRA, Toulouse) SMART (EMBL) PRINTS (University of Manchester) Hidden Markov Models: theory HMMER 2.1.1: to build up HMMs Hidden Markov Models: links
Multiple Sequence Alignments
Clustalw at EBI Clustalw at Pasteur MultAlin Match-Box Dialign2 (2 sequences) Blast2 (2 sequences) Jalview
Protein Analysis
Compute pI/Mw ORF finder at NCBI TranslatER: Translate a DNA sequence SAPS: Statistical Analysis of Protein Sequences ProtScale: hydrophilicity/hydrophobicity
Protein Pathway Analysis
DIP: Database of Protein Interactions KEGG: Kyoto encyclopedia of genes and genomes MIPS: yeast pathways Transpath: signal transduction database CSNDB: Cell signaling
Protein Secondary Structure
PDB (Protein Data Bank) CATH (UCL) SCOP (MRC-LMB) FSSP (EBI) AGADIR (EMBL) HNN (Pole Bio-Informatique Lyonnais) SwissModel (ExPaSy) CPH (Technical University of Denmark)
Genome Sequencing
TIGR: The Institute for Genomic Research Proteome Inc. (YPD, WormPD) MIPS: Munich Information Center for Protein Sequences Stanford genomic resources (SGD,ATdb) GOLD v.1.0: Genomes On Line Database Genome analysis (MRC LMB)
Repetitive DNA
Satellites: Identifies satellites and periodic repetitions Repeats: Microsatellite-type regions
Analysis of regulatory regions
MatInspector: binding site prediction Promoter Scan:promoter prediction Signal Scan TFBIND PROMO The Promoter Database of Saccharomyces cerevisiae Pratt: Find patterns Jaak Vilo homepage:expression, clustering, patterns TRANSFAC: Transcription Factor Database EiPD: Eukaryotic Promoter Database Genome-Wide Expression:Young's lab TRRD:Transcription Regulatory Regions Database, Nobosibirsk GeneExpress system,Nobosibirsk TRADAT: TRAnscription Database and Analysis Tools Muscle-Specific Regulation of Transcription
Statistics
Statistics programs The Statistics of Sequence Similarity Scores
CPAN Perl Bioperl