SGPP

The National Institute of General Medical Sciences of the NIH has awarded a four-year grant for a Structural Genomics of Pathogenic Protozoa (SGPP) Consortium. The SGPP consortium consists of investigators from our lab and from the University of Washington, University of Rochester, Hauptman-Woodward Medical Research Institute, Lawrence Berkeley National Laboratory, and Stanford University. The consortium aims to develop methods and technologies for determining protein structures in the protozoan species L. major, Plasmodium falciparum, Trypanosoma brucei and T. cruzi that cause the tropical diseases as Leishmaniasis, malaria, sleeping sickness, and Chagas' disease. The major thrust of this project is to map new sequence- fold relationships. The resultant protein structures will also aid in the identification of possible drug and/or vaccine targets.

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