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Seattle Structural Genomics Center for Infectious Disease

AcbaC.00008.a: glycine hydroxymethyltransferase

Target Characteristics

from organism: Acinetobacter baumannii AB5075-UW
most recent status: in PDB
center reference id: AcbaC.00008.a
is community request: True
associated disease:
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
unclassified

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
AcbaC.00008.a.B1.GE38569 full length 1 417 GE38569
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
AcbaC.00008.a.B1.PW37629 full length 1 417

Structures

image of structure for 5VMB
5VMB
Deposited: 4/27/2017
Determination: XRay
Diffraction Image
Clone: AcbaC.00008.a.B1.GE38569
Protein: AcbaC.00008.a.B1.PW37629

External Resources

Resource Reference ID
GenBank: AKA31079.1
PATRIC ID: fig|470.1345.peg.1292
PGAT: acinetobacter:ABUW_1333
RefSeq: WP_000457893.1
UniProt: V5VBJ2

Enzyme & Pathway Information

Pathway Pathway ID EC Number
N10-formyl-tetrahydrofolate biosynthesis 1CMET2-PWY 2.1.2.1
glycine biosynthesis I GLYSYN-PWY 2.1.2.1
formaldehyde assimilation I (serine pathway) PWY-1622 2.1.2.1
photorespiration PWY-181 2.1.2.1
folate polyglutamylation PWY-2161 2.1.2.1
folate transformations I PWY-2201 2.1.2.1
glycine betaine degradation I PWY-3661 2.1.2.1
glycine betaine degradation II (mammalian) PWY-3661-1 2.1.2.1
folate transformations II PWY-3841 2.1.2.1
purine nucleobases degradation II (anaerobic) PWY-5497 2.1.2.1
superpathway of L-serine and glycine biosynthesis I SER-GLYSYN-PWY 2.1.2.1

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MFANISISEF DPELAQAIAS EDERQEAHIE LIASENYCSP AVMEAQGSKL TNKYAEGYPG KRYYGGCEFV DVIEQMAIDR AKELFGADYA NVQPHAGSQA NSAVYLALLN PGDTVLGMSL AHGGHLTHGA KVSFSGKTYN AVQYGLNAET GEIDYEEVER LALEHKPRMI VAGFSAYSRV VDWQRFRDIA DKVGAYLFVD MAHVAGLVAA GVYPNPVQIA DVTTTTTHKT LRGPRSGLIL AKANEEIEKK LQSAVFPGNQ GGPLMHAIAA KAICFKEAMS DDFKAYQQQV VKNAQAMAEV FIARGYDVVS GGTDNHLFLL SLIKQDVTGK DADAWLGAAH ITVNKNSVPN DPRSPFVTSG IRIGTPAVTT RGFGEAEVRE LAGWIADVID SKGDEKVIAD VKAKVEAVCA KFPVYAK

NT Sequence
ATGTTTGCCA ATATTTCCAT TTCTGAATTT GATCCAGAAT TAGCTCAAGC AATTGCTTCT GAAGATGAGC GTCAAGAAGC ACATATCGAG TTAATTGCAT CTGAAAACTA TTGCTCTCCT GCGGTAATGG AAGCGCAAGG ATCAAAACTT ACGAACAAAT ACGCAGAAGG TTATCCTGGC AAACGCTATT ATGGCGGTTG CGAATTTGTA GATGTTATTG AGCAAATGGC GATTGACCGT GCTAAAGAAC TTTTTGGTGC AGATTACGCA AACGTTCAAC CACACGCTGG CTCACAAGCT AACTCTGCTG TTTATTTAGC GCTTCTTAAC CCGGGCGATA CAGTTTTAGG TATGAGCTTG GCTCACGGTG GTCACTTGAC TCACGGTGCA AAAGTAAGCT TCTCTGGTAA AACGTATAAC GCTGTTCAGT ATGGTCTAAA TGCTGAAACT GGTGAGATTG ATTACGAAGA AGTTGAACGT TTAGCATTGG AACACAAGCC ACGTATGATC GTTGCTGGTT TCTCTGCTTA TAGCCGTGTT GTAGATTGGC AACGTTTCCG TGACATCGCG GACAAAGTTG GTGCTTACCT TTTTGTTGAT ATGGCTCACG TTGCTGGTCT TGTTGCTGCT GGTGTATATC CAAACCCAGT TCAAATTGCT GACGTAACAA CAACGACGAC TCACAAAACA CTTCGTGGTC CACGTTCTGG TTTAATCCTT GCGAAAGCAA ATGAAGAAAT CGAGAAAAAA CTTCAATCAG CTGTATTCCC TGGTAACCAA GGCGGTCCAT TAATGCATGC GATTGCTGCT AAAGCAATCT GCTTCAAAGA AGCAATGTCT GACGACTTTA AAGCTTACCA ACAACAAGTT GTGAAAAATG CTCAAGCAAT GGCTGAAGTA TTCATTGCTC GTGGTTATGA TGTTGTTTCT GGTGGTACAG ACAACCACTT ATTCTTGTTA TCTTTAATCA AACAAGACGT AACTGGTAAA GATGCAGACG CTTGGTTAGG TGCTGCTCAC ATTACTGTGA ACAAAAACTC AGTTCCAAAT GACCCACGTT CTCCATTTGT GACTTCTGGT ATCCGTATCG GTACTCCGGC AGTAACAACT CGTGGTTTTG GTGAAGCTGA AGTTCGTGAA CTTGCTGGTT GGATCGCTGA CGTGATTGAC AGCAAAGGTG ACGAAAAAGT TATTGCTGAT GTAAAAGCAA AAGTTGAAGC TGTTTGTGCA AAATTCCCTG TATATGCAAA ATAA

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