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Seattle Structural Genomics Center for Infectious Disease

AcbaC.00137.b: UDP-N-acetylmuramate--alanine ligase

Target Characteristics

from organism: Acinetobacter baumannii AB5075-UW
most recent status: in PDB
center reference id: AcbaC.00137.b
is community request: True
associated disease:
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
unclassified

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
AcbaC.00137.b.B4.GE40443 truncation 3 10 482 GE40443
AcbaC.00137.b.B5.GE40444 truncation 4 19 482 GE40444
AcbaC.00137.b.B6.GE40445 truncation 5 29 482 GE40445
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
AcbaC.00137.b.B6.PS38212 truncation 5 29 482

Structures

image of structure for 6CAU
6CAU
Deposited: 1/31/2018
Determination: XRay
Diffraction Image
Clone: AcbaC.00137.b.B5.GE40444
Protein: AcbaC.00137.b.B5.PD00479

Citations by Others


This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
GenBank: AKA29942.1
PATRIC ID: fig|470.1345.peg.143
PGAT: acinetobacter:ABUW_0147
RefSeq: WP_000075472.1
UniProt: V5V8V9

Enzyme & Pathway Information

Pathway Pathway ID EC Number
peptidoglycan biosynthesis I (meso-diaminopimelate containing) PEPTIDOGLYCANSYN-PWY 6.3.2.8
peptidoglycan biosynthesis II (staphylococci) PWY-5265 6.3.2.8
peptidoglycan biosynthesis III (mycobacteria) PWY-6385 6.3.2.8
UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing) PWY-6386 6.3.2.8
UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing) PWY-6387 6.3.2.8
peptidoglycan biosynthesis V (beta-lactam resistance) PWY-6470 6.3.2.8
peptidoglycan biosynthesis IV (Enterococcus faecium) PWY-6471 6.3.2.8
UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing) PWY-7953 6.3.2.8

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSPTTAANQA KKLIKVPEMR RIKHIHFVGI GGAGMCGIAE VLANQGYKIS GSDIKASKTT QQLEENGIKV YIGHEAENIK NANVLVVSTA IDPENPEVKA AIEQRIPIVR RAEMLGELMR YRHGIAVAGT HGKTTTTSLL TTMLAEENLD PTYVIGGLLN STGVNAALGE SRFIVAEADE SDASFLYLQP MAAIVTNIDA DHMDTYEGSF DKLKDTFVQF LHNLPFYGLA VVCGDDANIR EILPRVGRPV ITYGFNEDND IRAIDVEQDG MRSHFTVLRK GREPLRLTIN QPGLHNVLNA LAAIGVATDE GVSDEAISRA LKGFSGVGRR FQVQGEFELG EGNVKLVDDY GHHPKEVEAT IKAARQSHPD RRLVMLFQPH RYSRTRDCFD DFIEVLSQVD QLLLLEVYPA GEKPIVGADS RTLARSIRLR GQVEPILIDP VEGNLQNIMQ NVLQPNDLLL TQGAGNVGAI SVELAQHHLY VK

NT Sequence
ATGTCTCCAA CAACAGCTGC GAACCAAGCA AAAAAACTGA TTAAAGTGCC TGAAATGCGC CGTATCAAAC ACATTCATTT TGTGGGAATT GGCGGTGCAG GTATGTGTGG TATTGCTGAG GTGTTAGCTA ACCAAGGATA TAAAATTTCC GGTTCAGATA TTAAGGCATC AAAAACCACA CAACAATTAG AAGAAAATGG CATTAAGGTC TATATCGGAC ACGAAGCAGA AAATATTAAA AATGCAAATG TGCTTGTCGT GTCAACAGCA ATTGACCCGG AAAATCCGGA AGTTAAAGCT GCCATTGAAC AACGTATTCC GATTGTACGT CGTGCAGAAA TGCTCGGTGA ACTTATGCGT TACCGTCATG GTATTGCTGT GGCAGGTACA CATGGTAAAA CTACAACCAC AAGTCTTTTG ACGACAATGT TGGCGGAAGA AAACCTCGAC CCAACTTATG TGATCGGTGG TTTACTTAAC AGTACAGGCG TAAATGCAGC ACTGGGTGAA AGCCGCTTTA TTGTTGCTGA AGCTGACGAA TCGGATGCAT CTTTCCTTTA TTTACAGCCA ATGGCAGCGA TTGTAACCAA CATTGATGCT GACCATATGG ATACTTATGA AGGCAGTTTC GATAAATTAA AAGATACCTT CGTACAGTTC CTTCATAACT TACCATTCTA CGGCTTGGCT GTGGTTTGTG GCGATGATGC GAACATCCGC GAGATTTTGC CACGTGTAGG CCGTCCGGTT ATTACTTATG GTTTTAATGA AGATAATGAC ATCCGTGCTA TCGATGTAGA GCAAGATGGT ATGCGTTCGC ACTTTACTGT TTTACGTAAA GGACGTGAGC CGTTACGTCT AACTATTAAT CAACCGGGTT TACATAACGT TTTAAATGCT TTGGCTGCAA TTGGTGTTGC AACTGATGAA GGCGTTTCGG ATGAAGCAAT TAGCCGTGCA TTAAAAGGTT TTAGTGGTGT TGGACGTCGC TTCCAAGTAC AAGGTGAATT TGAACTTGGT GAAGGGAATG TAAAATTAGT CGATGACTAT GGGCATCATC CTAAAGAAGT GGAAGCTACG ATTAAAGCTG CTCGTCAGAG CCATCCTGAT CGTCGTTTAG TTATGCTTTT CCAACCACAC CGTTACTCTC GTACACGTGA TTGTTTTGAT GACTTTATTG AAGTTTTATC TCAAGTCGAC CAATTATTAT TACTAGAAGT TTATCCGGCT GGGGAAAAAC CAATTGTTGG CGCAGATAGC CGTACTTTGG CGCGTAGTAT TCGCTTGCGT GGTCAGGTTG AACCGATTTT GATTGATCCG GTTGAAGGTA ATTTGCAAAA CATCATGCAA AATGTGTTAC AACCAAATGA CTTGTTATTA ACGCAAGGTG CAGGTAACGT GGGAGCAATT TCAGTAGAAC TTGCACAGCA CCATTTGTAT GTGAAATAA

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