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Seattle Structural Genomics Center for Infectious Disease

AcbaC.01152.a: uroporphyrinogen decarboxylase

Target Characteristics

from organism: Acinetobacter baumannii AB5075-UW
most recent status: in PDB
center reference id: AcbaC.01152.a
is community request: True
associated disease:
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
unclassified

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
AcbaC.01152.a.B1.GE38681 full length 1 357 GE38681
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
AcbaC.01152.a.B1.PW37671 full length 1 357

Structures

image of structure for 4ZR8
4ZR8
Deposited: 5/11/2015
Determination: XRay
Diffraction Image
Clone: AcbaC.01152.a.B1.GE38681
Protein: AcbaC.01152.a.B1.PW37671

Citations by Others


This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
GenBank: AKA30941.1
PATRIC ID: fig|470.1345.peg.1154
PGAT: acinetobacter:ABUW_1190
RefSeq: WP_000209397.1
UniProt: V5VBG6

Enzyme & Pathway Information

Pathway Pathway ID EC Number
3,8-divinyl-chlorophyllide a biosynthesis I (aerobic, light-dependent) CHLOROPHYLL-SYN 4.1.1.37
heme b biosynthesis I (aerobic) HEME-BIOSYNTHESIS-II 4.1.1.37
heme b biosynthesis II (anaerobic) HEMESYN2-PWY 4.1.1.37
superpathway of heme b biosynthesis from uroporphyrinogen-III PWY0-1415 4.1.1.37
superpathway of bacteriochlorophyll a biosynthesis PWY-5529 4.1.1.37
3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic) PWY-5531 4.1.1.37
superpathay of heme b biosynthesis from glutamate PWY-5918 4.1.1.37
superpathway of b heme biosynthesis from glycine PWY-5920 4.1.1.37
3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent) PWY-7159 4.1.1.37
heme b biosynthesis IV (Gram-positive bacteria) PWY-7766 4.1.1.37

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MTTLKNDRFL RALLREPVDT TPIWMMRQAG RYLPEYRETR SKAGDFLSLC KNTEFACEVT LQPLRRYDLD AAILFSDILT IPDALGLGLY FETGEGPKFH KTVRTEQDVA NLPKLNAKAD LDYVMNAVST IRSALGGQVP LIGFSGSPWT LATYMVEGGS SKEFRFTKQM MYAQPEVLHA LLDHLADSVI DYLNAQIDAG AQAIQIFDSW GGALAHREYV EFSLNYMKKI IAGLQREKDG RRIPVIVFTK GGGQWLEPMI TTGADALGLD WTTPLNTART TVAGRVALQG NLDPAVLYGS AASIEKAVKA MLDDAYANGE KTGYVANLGH GITQWVDPAQ PKIFVDTVHE YSAKYLG

NT Sequence
ATGACGACAC TTAAAAATGA TCGTTTCTTA CGTGCTTTAT TACGTGAGCC TGTAGATACC ACTCCAATAT GGATGATGCG CCAAGCAGGA CGTTATTTGC CTGAATATCG GGAAACACGC TCAAAAGCTG GTGACTTTCT ATCTTTATGC AAAAATACAG AATTTGCTTG TGAAGTGACT TTACAGCCTT TGCGTCGCTA CGATTTAGAC GCAGCAATTT TATTTTCAGA TATTTTAACT ATTCCAGACG CATTAGGACT TGGACTGTAT TTTGAAACTG GAGAAGGTCC GAAGTTTCAT AAAACGGTAC GTACTGAACA AGATGTGGCT AACTTACCTA AGCTTAATGC TAAAGCCGAT CTTGATTATG TCATGAACGC AGTAAGTACG ATTCGTTCTG CTTTAGGTGG ACAAGTTCCA CTGATTGGTT TTTCGGGTAG TCCTTGGACA CTGGCGACTT ATATGGTTGA AGGCGGTTCA AGCAAAGAGT TCCGTTTTAC CAAGCAAATG ATGTATGCGC AGCCAGAAGT TTTGCATGCG TTGCTCGACC ATTTAGCAGA TTCAGTCATT GATTACTTAA ATGCGCAAAT TGATGCAGGC GCTCAGGCAA TTCAAATCTT TGATAGTTGG GGTGGGGCTT TAGCACACCG TGAATATGTA GAGTTCTCTC TTAACTATAT GAAGAAGATT ATCGCGGGCT TACAACGTGA AAAAGATGGA CGCCGTATTC CAGTGATTGT GTTCACTAAA GGTGGCGGTC AATGGTTAGA ACCAATGATC ACGACAGGTG CCGATGCATT AGGGCTGGAC TGGACGACAC CATTAAATAC GGCTCGAACC ACGGTGGCAG GTCGTGTTGC CCTACAAGGG AACCTTGACC CGGCTGTTTT ATATGGTTCG GCGGCTTCAA TTGAAAAAGC TGTAAAAGCA ATGTTAGATG ATGCTTATGC AAACGGTGAG AAGACCGGTT ATGTTGCTAA CTTAGGGCAC GGTATTACCC AATGGGTAGA TCCGGCGCAG CCAAAAATCT TTGTAGATAC GGTACATGAA TATAGTGCTA AATATCTAGG ATAG

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