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Seattle Structural Genomics Center for Infectious Disease

AcbaC.18002.a: glutamine-dependent NAD+ synthetase

Target Characteristics

from organism: Acinetobacter baumannii AB5075-UW
most recent status: in PDB
center reference id: AcbaC.18002.a
is community request: True
associated disease:
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
unclassified

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
AcbaC.18002.a.B1.GE38871 full length 1 541 GE38871
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Structures

image of structure for 5KHA
5KHA
Deposited: 6/14/2016
Determination: XRay
Diffraction Image
Clone: AcbaC.18002.a.B1.GE38871
Protein: AcbaC.18002.a.B1.PS02475

Citations by Others


This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
GenBank: AKA32782.1
PATRIC ID: fig|470.1345.peg.3020
PGAT: acinetobacter:ABUW_3069
RefSeq: WP_000834616.1
UniProt: V5VHL3

Enzyme & Pathway Information

Pathway Pathway ID EC Number
aspartate superpathway PWY0-781 6.3.1.5
NAD de novo biosynthesis I (from aspartate) PYRIDNUCSYN-PWY 6.3.1.5
NAD de novo biosynthesis II (from tryptophan) NADSYN-PWY 6.3.5.1
aspartate superpathway PWY0-781 6.3.5.1
superpathway of NAD biosynthesis in eukaryotes PWY-3502 6.3.5.1
pyridine nucleotide cycling (plants) PWY-5381 6.3.5.1
NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde PWY-5653 6.3.5.1
NAD salvage pathway II (PNC IV cycle) PWY-7761 6.3.5.1
NAD salvage pathway I (PNC VI cycle) PYRIDNUCSAL-PWY 6.3.5.1
NAD de novo biosynthesis I (from aspartate) PYRIDNUCSYN-PWY 6.3.5.1

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MKSFKVALAQ FSPHIGNIDS NTQKMIEQAN QAKKQDADLI IFPELSVIGY PAEDLLLRPN LNKRMQKAFA QLSEVKDIVM VFGFVNQTED GQRYNSAAVM KDGQVLGVFN KHNLPNYGVF DEKRYFQKGH QHLVFEYLGH KFGVLICEDI WSINTVKQLS QLNVDTVLVL NSSPYEVGKP QHRKQTLSEL AKQLHLNIVY VNQVGGQDDL IFDGTSFVSN QNGEIALQAP SFKEDLYIAE FDRDTKLYKV VESAPALETF AEIYQGLVMA TRDYVERSGF PGVILGLSGG IDSALTLAIA VDAIGAERVQ AVMMPYTYTS QISVEDAAEQ ARRMGVTFGI AEIHSIVNSF MQTLYPFFGN SPADATEENL QARARGTLLM GLSNKFGNLV LSTGNKSELS VGYCTLYGDM VGGFAVLKDV YKTIVFELAK YRNSLSETPV IPERVITRPP SAELRPDQKD QDSLPAYDVL DAILYAYIEE DLGQADIIAK GFDKEVVEKV IRLVDRNEYK RRQGAIGPRI TSRAFSRERR YPIVNGWTAN D

NT Sequence
ATGAAAAGTT TTAAAGTTGC CCTTGCTCAG TTTTCTCCGC ATATTGGCAA TATTGACTCA AACACCCAAA AGATGATTGA GCAAGCAAAT CAGGCGAAAA AACAAGACGC TGACCTGATT ATTTTTCCTG AGCTTTCTGT GATTGGTTAT CCAGCTGAAG ACTTATTGTT ACGTCCAAAT TTAAATAAGC GGATGCAAAA GGCTTTTGCT CAACTTAGTG AAGTTAAAGA TATTGTGATG GTTTTCGGCT TCGTAAACCA GACAGAAGAT GGCCAACGTT ATAATTCAGC TGCTGTCATG AAAGACGGTC AGGTTTTAGG TGTCTTCAAT AAACATAACT TGCCAAACTA TGGCGTTTTT GATGAAAAAC GTTATTTCCA AAAAGGCCAT CAGCACTTGG TATTTGAGTA CTTAGGCCAT AAGTTTGGTG TACTCATTTG TGAAGATATC TGGTCAATCA ATACAGTAAA ACAATTAAGC CAATTAAATG TTGATACTGT ACTTGTGCTT AATTCATCGC CATATGAAGT GGGTAAACCA CAGCATCGTA AACAGACATT AAGTGAGCTT GCAAAGCAGC TTCATTTAAA TATTGTTTAT GTTAACCAAG TTGGTGGACA AGATGATTTA ATTTTTGATG GTACAAGTTT TGTTAGCAAT CAAAATGGTG AAATTGCTTT ACAAGCACCT AGCTTTAAAG AAGATCTCTA TATTGCTGAA TTTGACCGCG ATACAAAACT ATATAAAGTT GTCGAGTCTG CTCCTGCATT AGAAACTTTT GCAGAGATCT ATCAAGGCCT AGTCATGGCA ACACGTGACT ATGTAGAACG CTCAGGTTTT CCTGGAGTAA TTTTAGGTCT TTCTGGTGGT ATTGACTCTG CCCTTACGCT TGCTATCGCA GTTGATGCAA TCGGTGCAGA GAGAGTTCAA GCTGTGATGA TGCCATATAC TTACACTTCT CAAATTAGTG TAGAAGATGC AGCGGAACAA GCTCGCCGTA TGGGCGTGAC TTTCGGTATT GCCGAAATTC ATTCAATCGT AAATAGCTTC ATGCAAACTT TGTATCCGTT CTTTGGTAAT TCACCAGCCG ATGCGACTGA AGAAAATTTA CAAGCGCGCG CTCGTGGCAC ATTGCTTATG GGCTTATCTA ACAAGTTTGG TAATTTAGTT CTTTCTACAG GTAATAAATC TGAACTTTCA GTTGGCTATT GCACACTTTA CGGTGACATG GTGGGTGGCT TTGCTGTTCT CAAAGATGTT TATAAAACAA TCGTGTTTGA ATTAGCAAAA TACCGTAATA GCTTAAGTGA AACTCCGGTT ATTCCTGAGC GTGTAATTAC TCGCCCACCT TCAGCAGAAC TGCGTCCAGA TCAAAAAGAC CAAGACTCTT TACCAGCGTA TGATGTATTG GATGCTATCC TTTATGCATA CATTGAGGAA GATTTAGGTC AGGCAGACAT TATTGCCAAA GGTTTTGATA AAGAAGTTGT TGAAAAAGTC ATCCGTTTAG TTGATCGTAA TGAATATAAA CGTCGTCAAG GTGCGATTGG CCCGAGAATT ACTTCTCGTG CATTTAGTCG CGAACGACGT TATCCGATTG TCAACGGTTG GACAGCGAAT GACTGA

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