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Seattle Structural Genomics Center for Infectious Disease

AccaA.19900.a: Glucokinase

Target Characteristics

from organism: Acanthamoeba castellanii
most recent status: purified
center reference id: AccaA.19900.a
is community request: True
associated disease: Amoebic keratitis and encephalomyelitis
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
I

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Molecular models

Method Results
comparative modelling Robetta_10690

External Resources

Resource Reference ID
EuPathDB: AmoebaDB:ACA1_177380
UniProt: L8GT25

Enzyme & Pathway Information

Pathway Pathway ID EC Number
trehalose degradation II (trehalase) PWY0-1182 2.7.1.2

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MTSAPPLPIS TLVDIVEEAR PALLQWKDRF KESLKYFVGV DIGGTNTRVA LDTGSSDESY VQIAKFRASS SKHIVEGLQQ VARQVADILG VPASGACLAG AGRISDDGLS LDITNYPGTP ADRTLTSDQL PTYLFPADAT HFINDLESTC YGLKSLNESQ QLSSFFKPLW STSDTVMPME FGHALYSPAT DPSKKDEEDR LAAYLSKTLY SGKHAIEYED IVSGRGVLAV YQWITAEHKE AAKYESAEEV STAAFREDPC PFATKALLIH YRFLMRVAKN LCVGLQAKGM FLAGDNQVVN NPFFEKHLPE MRAEFLDHPK PDWIDMVELY TQTESFNINL HGALYYARTD QR

NT Sequence
atgaccagcg ctccgccact tcccatctcc acgctcgttg acattgtcga ggaggctcgg ccggccctcc ttcagtggaa ggatcgattc aaggagagcc tgaagtactt cgtgggtgtc gatattggtg gcaccaacac gcgcgtggcg ctcgacaccg gctcctccga cgagtcctac gtccagatcg ccaagttcag ggcgtcgagc agcaagcaca tcgttgaggg actccagcag gtcgcccgtc aggtggccga catcctcggc gtccctgcct cgggcgcctg tcttgccggc gccggccgca tcagcgacga tggcctctcg cttgatatca ccaactaccc cggtacccct gccgaccgca cgctgacctc ggatcagctc ccgacctacc tgttccccgc tgatgcgaca cacttcatca atgacctcga aagcacgtgc tacggcctca agtcccttaa cgagagccag cagctctcct ccttcttcaa gcccctctgg tccacctcgg acaccgtgat gcccatggag ttcggccacg ccctctactc gccggccacc gacccctcca agaaggacga ggaggaccgg ctcgcggcct acctctcgaa gactctctac agcggcaagc acgccatcga gtacgaggac atcgtatcgg gccgcggcgt cctggccgtc taccagtgga tcaccgccga gcacaaggag gctgccaagt atgagtcggc cgaggaggtc agcacggccg ccttccgcga ggacccgtgc cccttcgcca ccaaggcgct gctcatccac tacaggttcc tgatgcgtgt ggccaagaac ctctgcgtgg ggctgcaggc caagggcatg ttccttgccg gtgacaacca ggtggtaaac aaccccttct tcgagaagca cctgccggag atgagggccg agtttttgga tcaccccaag cccgactgga tcgacatggt ggagctctac acccagacgg agagcttcaa catcaacctc cacggcgccc tctactacgc gcgtaccgac cagcgctga

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