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Seattle Structural Genomics Center for Infectious Disease

AnphA.00168.a: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (IspD/ YgbP)

Target Characteristics

from organism: Anaplasma phagocytophilum HZ
most recent status: selected
center reference id: AnphA.00168.a
is community request: False
associated disease: Human granulocytic anaplasmosis
NIH risk group: 1
is select agent: False
NIH priority
pathogens category:
I

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

External Resources

Resource Reference ID
OrthoMCL: OG5_130616
PATRIC ID: fig|212042.8.peg.1368
RefSeq: YP_505794.1
UniProt: Q2GIK7

Enzyme & Pathway Information

Pathway Pathway ID EC Number
methylerythritol phosphate pathway I NONMEVIPP-PWY 2.7.7.60
superpathway of geranylgeranyl diphosphate biosynthesis II (via MEP) PWY-5121 2.7.7.60
isoprene biosynthesis I PWY-6270 2.7.7.60
superpathway of ergosterol biosynthesis II PWY-7156 2.7.7.60
taxadiene biosynthesis (engineered) PWY-7392 2.7.7.60
methylerythritol phosphate pathway II PWY-7560 2.7.7.60

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MPLFVVLIVA AGESRRLGNK NQLKQYLRIQ RHSVLAHTIT QMVTSFVHSV KVVIGQGQDA FYEHSLLSLP KKVTDLLIPP VYGGARRQDS VRIGLESIEH INPEFVIIHD ACRPFASLPS ADVITYHLRD HAGIVPVLQP SDTISRVENS VIMEEIAKDS VRIVQTPQIY RYKDILRCHK EVYSTDPEKY FSDESSVMVA CGMSVITTEG DYNNFKITTA EDVTRAELYM QHMGS

NT Sequence
ATGCCTCTTT TCGTTGTACT TATAGTAGCT GCTGGAGAAA GCAGGAGATT GGGAAATAAG AACCAACTGA AGCAATATCT CAGGATTCAA CGTCATTCTG TGCTTGCGCA TACCATCACT CAGATGGTTA CTTCATTTGT ACATTCTGTG AAGGTTGTGA TCGGACAGGG GCAGGATGCT TTCTACGAAC ATTCCCTCTT ATCTCTTCCT AAAAAGGTGA CGGATTTGCT TATACCACCA GTATATGGTG GAGCTCGCAG ACAAGATTCT GTGCGCATAG GTTTGGAAAG CATTGAACAC ATTAATCCAG AATTTGTAAT AATACATGAT GCCTGTCGCC CTTTTGCTAG TTTGCCAAGT GCTGACGTTA TAACTTACCA TCTACGGGAT CATGCTGGGA TTGTACCTGT TTTGCAGCCT AGCGATACCA TAAGTCGGGT TGAAAACTCA GTTATTATGG AGGAAATAGC GAAGGATTCC GTTAGAATAG TTCAGACACC TCAAATATAC AGGTACAAGG ATATTTTGAG ATGTCACAAA GAAGTTTACA GCACAGATCC GGAGAAATAT TTCTCAGATG AGTCATCAGT AATGGTAGCG TGTGGGATGT CAGTTATCAC TACAGAGGGA GATTATAACA ACTTTAAGAT TACTACCGCC GAGGATGTTA CTAGGGCTGA GTTGTATATG CAACACATGG GTAGT

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