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Seattle Structural Genomics Center for Infectious Disease

AnphA.00316.a: tRNA (guanine-N1)-methyltransferase

Target Characteristics

from organism: Anaplasma phagocytophilum HZ
most recent status: in PDB
center reference id: AnphA.00316.a
is community request: False
associated disease: Human granulocytic anaplasmosis
NIH risk group: 1
is select agent: False
NIH priority
pathogens category:
I

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
AnphA.00316.a.A1.GE26664 Full length( AnphA.00316.a ) 1 232 GE26664
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Structures

image of structure for 3KNU
3KNU
Deposited: 11/12/2009
Determination: XRay
Diffraction Image
Clone: AnphA.00316.a.A1.GE26664
Protein: AnphA.00316.a.A1.PS00323
image of structure for 4IG6
4IG6
Deposited: 12/16/2012
Determination: XRay
Diffraction Image
Clone: AnphA.00316.a.A1.GE26664
Protein: AnphA.00316.a.A1.PS00323

Citations by Others

Landscape of Intertwined Associations in Multi-Domain Homo-Oligomeric Proteins
SS MacKinnon, SJ Wodak - Journal of molecular biology, 2015 - Elsevier
cited by: 10 others
PDB: 3KNU

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
OrthoMCL: OG5_132581
PATRIC ID: fig|212042.8.peg.1358
RefSeq: YP_505786.1
UniProt: Q2GIL5

Enzyme & Pathway Information

Pathway Pathway ID EC Number
tRNA methylation (yeast) PWY-6829 2.1.1.228
wybutosine biosynthesis PWY-7283 2.1.1.228
methylwyosine biosynthesis PWY-7285 2.1.1.228
7-(3-amino-3-carboxypropyl)-wyosine biosynthesis PWY-7286 2.1.1.228
2.1.1.31

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MIFNVLTIFP QMFPGPLGVS NLGSALKKGL WTLNVFDIRA FANNKHNTVD DTPYGGGPGM LLRADVLGRC IDEVLSLHPN TKLMFTSPRG VSFTQDIARQ TMNFDNITLL CGRFEGIDER VVDFYKLQEV SIGDYVLSGG ELAAMVIIDT CVRMVPGVIG NAESLKQESM EGSLEYPQYT RPASWKGMEV PEVLLTGNHG EIEKWRRNAS LSITAARRPD LLKDRYGEND VE

NT Sequence
ATGATCTTCA ACGTTCTAAC AATCTTTCCG CAAATGTTTC CCGGCCCTCT TGGCGTATCT AATCTGGGTT CTGCTCTGAA AAAAGGGCTG TGGACGTTGA ACGTTTTTGA TATTAGAGCC TTTGCGAATA ATAAACATAA TACTGTTGAT GATACCCCTT ATGGAGGGGG GCCAGGCATG CTTCTCAGGG CCGATGTGTT GGGAAGATGC ATAGATGAAG TTTTGTCTCT GCATCCGAAT ACTAAACTTA TGTTTACTTC TCCTCGAGGT GTAAGTTTTA CTCAAGATAT CGCTAGACAA ACTATGAATT TTGACAATAT AACCTTACTC TGCGGGCGCT TTGAAGGTAT TGATGAGAGA GTGGTAGATT TTTACAAATT GCAGGAAGTT AGCATAGGAG ATTATGTTCT CTCTGGTGGT GAGTTAGCTG CAATGGTAAT TATCGACACG TGTGTTAGAA TGGTGCCAGG AGTTATAGGT AATGCAGAGA GCTTAAAGCA GGAAAGTATG GAGGGTAGCC TTGAATACCC CCAGTATACT AGGCCAGCTT CCTGGAAGGG GATGGAGGTT CCAGAGGTCC TTCTTACTGG GAATCATGGA GAAATAGAAA AGTGGAGACG AAATGCTTCT CTTTCGATTA CTGCTGCAAG ACGACCGGAC TTGCTAAAAG ATAGATATGG TGAAAATGAC GTGGAA

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