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Seattle Structural Genomics Center for Infectious Disease

AnphA.00677.a: phosphoribosylglycinamide formyltransferase

Target Characteristics

from organism: Anaplasma phagocytophilum HZ
most recent status: in PDB
center reference id: AnphA.00677.a
is community request: False
associated disease: Human granulocytic anaplasmosis
NIH risk group: 1
is select agent: False
NIH priority
pathogens category:
I

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
AnphA.00677.a.A1.GE26653 Full length( AnphA.00677.a ) 1 211 GE26653
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
AnphA.00677.a.A1.PS00239 Full length( AnphA.00677.a ) 1 211

Structures

image of structure for 3KCQ
3KCQ
Deposited: 10/21/2009
Determination: XRay
Diffraction Image
Clone: AnphA.00677.a.A1.GE26653
Protein: AnphA.00677.a.A1.PS00239

Citations by Others

Structures and reaction mechanisms of the two related enzymes, PurN and PurU
G Sampei, M Kanagawa, S Baba? - Journal of Biochemistry, 2013 - Jpn Biochemical Soc
PDB: 3KCQ

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
OrthoMCL: OG5_129694
PATRIC ID: fig|212042.8.peg.244
RefSeq: YP_504847.1
UniProt: Q2GLA4

Enzyme & Pathway Information

Pathway Pathway ID EC Number
superpathway of tetrahydrofolate biosynthesis and salvage FOLSYN-PWY 2.1.2.2
5-aminoimidazole ribonucleotide biosynthesis I PWY-6121 2.1.2.2
superpathway of 5-aminoimidazole ribonucleotide biosynthesis PWY-6277 2.1.2.2
tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate PWY-6613 2.1.2.2
superpathway of purine nucleotides de novo biosynthesis I PWY-841 2.1.2.2

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MKKELRVGVL ISGRGSNLEA LAKAFSTEES SVVISCVISN NAEARGLLIA QSYGIPTFVV KRKPLDIEHI STVLREHDVD LVCLAGFMSI LPEKFVTDWH HKIINIHPSL LPSFKGLNAQ EQAYKAGVKI AGCTLHYVYQ ELDAGPIIMQ AAVPVLREDT AESLASRILA AEHVCYPKGV KLIAQDKIKL CDDGTVQCTG EDELFLFQEN F

NT Sequence
GTGAAGAAGG AACTACGCGT AGGTGTATTG ATTTCTGGTA GGGGTTCTAA TCTTGAAGCG TTAGCTAAGG CGTTTTCGAC TGAAGAGTCC TCTGTTGTGA TTTCATGTGT TATTTCTAAT AATGCTGAAG CACGCGGGCT CTTGATCGCT CAGAGTTACG GAATTCCTAC CTTTGTAGTT AAGCGGAAAC CGCTGGATAT AGAGCATATC AGTACGGTAC TAAGGGAGCA TGATGTAGAT CTAGTGTGCC TTGCAGGATT CATGAGCATA CTGCCTGAAA AGTTTGTCAC AGATTGGCAT CACAAGATAA TTAACATTCA CCCTTCACTT CTCCCATCTT TTAAGGGATT AAATGCTCAG GAACAAGCCT ATAAAGCAGG TGTTAAAATA GCGGGGTGCA CCCTACATTA TGTATATCAA GAGCTTGATG CCGGTCCTAT AATAATGCAG GCTGCAGTGC CTGTGCTTAG AGAAGACACT GCTGAGAGTT TAGCTAGTCG TATTCTAGCT GCTGAGCACG TATGTTATCC CAAGGGTGTG AAGCTCATTG CTCAGGATAA AATCAAGCTT TGCGATGATG GCACTGTGCA ATGTACGGGC GAGGATGAGC TCTTCTTATT TCAGGAGAAC TTT

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