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Seattle Structural Genomics Center for Infectious Disease

AnphA.00921.a: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase

Target Characteristics

from organism: Anaplasma phagocytophilum HZ
most recent status: expressed
center reference id: AnphA.00921.a
is community request: False
associated disease: Human granulocytic anaplasmosis
NIH risk group: 1
is select agent: False
NIH priority
pathogens category:
I

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
AnphA.00921.a.A1.GE27002 Full length( AnphA.00921.a ) 1 176 GE27002
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

External Resources

Resource Reference ID
OrthoMCL: OG5_133110
PATRIC ID: fig|212042.8.peg.224
RefSeq: YP_504833.1
UniProt: Q2GLB8

Enzyme & Pathway Information

Pathway Pathway ID EC Number
superpathway of chorismate metabolism ALL-CHORISMATE-PWY 2.7.6.3
superpathway of tetrahydrofolate biosynthesis and salvage FOLSYN-PWY 2.7.6.3
6-hydroxymethyl-dihydropterin diphosphate biosynthesis I PWY-6147 2.7.6.3
tetrahydromethanopterin biosynthesis PWY-6148 2.7.6.3
superpathway of tetrahydrofolate biosynthesis PWY-6612 2.7.6.3
6-hydroxymethyl-dihydropterin diphosphate biosynthesis II (Methanocaldococcus) PWY-6797 2.7.6.3
6-hydroxymethyl-dihydropterin diphosphate biosynthesis III (Chlamydia) PWY-7539 2.7.6.3
6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium) PWY-7852 2.7.6.3
6-hydroxymethyl-dihydropterin diphosphate biosynthesis V (Pyrococcus) PWY-7853 2.7.6.3

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MVKQIYQPNK SAMVVLALGS NIGDRMSALK EAIKLIPLHN RLYSSVYESC ALLPDNAPFC WNMPFLNMVI AGYTHFSPED LLQSIKQIES QLGRCSLGHW SPRSIDIDII LWEGVTVEDK ALTIPHKEMH KRDFVLVPTC DICPRFPHPI LKETVESILL NKQDINLVKK YQAIHL

NT Sequence
ATGGTTAAAC AAATATATCA ACCCAACAAA AGTGCTATGG TTGTATTAGC ATTGGGCAGC AATATTGGCG ATAGGATGAG CGCTTTAAAA GAAGCAATAA AACTCATACC GTTGCATAAT AGACTATACT CATCCGTATA TGAGAGTTGT GCTTTGCTTC CTGATAACGC CCCATTTTGC TGGAACATGC CTTTTCTAAA CATGGTCATC GCGGGATATA CACATTTTTC TCCAGAAGAT CTCTTACAAA GCATTAAACA AATAGAATCC CAGCTAGGAA GATGTAGTCT TGGTCATTGG AGCCCTAGAA GCATAGATAT AGACATAATA TTGTGGGAAG GCGTTACAGT AGAGGATAAA GCTCTCACTA TACCTCATAA GGAAATGCAC AAACGTGACT TTGTTCTAGT ACCTACCTGC GACATATGTC CCCGTTTTCC ACATCCTATA CTAAAAGAAA CAGTAGAATC GATATTGCTA AATAAGCAGG ATATCAACCT TGTGAAAAAG TATCAGGCTA TACACTTA

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