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AnphA.00973.a: Deoxycytidine triphosphate deaminase

Target Characteristics

from organism: Anaplasma phagocytophilum HZ
most recent status: in PDB
center reference id: AnphA.00973.a
is community request: False
associated disease: Human granulocytic anaplasmosis
NIH risk group: 1
is select agent: False
NIH priority
pathogens category:
I

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
AnphA.00973.a.A1.GE27008 Full length( AnphA.00973.a ) 1 185 GE27008
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
AnphA.00973.a.A1.PW27048 Full length( AnphA.00973.a ) 1 185

Structures

image of structure for 3KM3
3KM3
Deposited: 11/9/2009
Determination: XRay
Diffraction Image
Clone: AnphA.00973.a.A1.GE27008
Protein: AnphA.00973.a.A1.PW27048

Publications by SSGCID

SAD phasing using iodide ions in a high-throughput structural genomics environment.
Abendroth J, Christensen JS, Edwards TE, Gardberg AS, Myler PJ, Robinson JI, Staker BL, Stewart LJ
J. Struct. Funct. Genomics - 2011
volume 12, issue 2, pages 83-95
PMID: 21359836; PMCID: PMC3123459

Citations by Others

Substructure determination using phase-retrieval techniques
P Skubk- Acta Crystallographica Section D: Structural Biology, 2018 - scripts.iucr.org
cited by: 5 others
PDB: 3KM3
Macromolecular X-ray structure determination using weak, single-wavelength anomalous data
G Bunkóczi, AJ McCoy, N Echols… - Nature …, 2014 - nature.com
PDB: 3KM3
Functional Exploration and Characterization of the Deaminases of Cog0402
DS Hitchcock - 2014 - oaktrust.library.tamu.edu
PDB: 3KM3

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
OrthoMCL: OG5_131757
PATRIC ID: fig|212042.8.peg.139
RefSeq: YP_504757.1
UniProt: Q2GLJ4

Enzyme & Pathway Information

Pathway Pathway ID EC Number
superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) PWY0-166 3.5.4.13
pyrimidine deoxyribonucleotides de novo biosynthesis II PWY-7187 3.5.4.13

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSVMPDHWIK ERALKDGMIS PFVDHKEGTG VLSYGLSSYG YDARLDNKFK IFANTHSVVV DPKNFSQDSF VDREGDFCII PPNSFMLAKT VEYFNIPRDV MVVCVGKSTY ARCGIVVNVT PLEPGWSGYV TLEFSNTSPL PVKVYAFEGA CQFLFFSGKE RCSKSYDEAG GKYMGQSDVT LPIIS

NT Sequence
ATGTCAGTCA TGCCTGATCA CTGGATCAAG GAAAGGGCCC TAAAAGATGG TATGATCTCC CCGTTCGTAG ACCACAAAGA AGGCACGGGT GTTTTGTCGT ATGGTTTGTC TTCCTATGGC TATGATGCTC GGCTGGATAA TAAGTTCAAG ATTTTTGCCA ATACACACTC AGTGGTAGTG GATCCTAAGA ACTTTTCGCA AGATAGCTTT GTTGATCGTG AAGGAGATTT CTGCATCATT CCACCAAACA GCTTTATGCT AGCCAAGACT GTAGAGTACT TTAACATCCC ACGAGACGTT ATGGTTGTTT GTGTTGGAAA GTCAACATAC GCTCGCTGTG GCATCGTAGT TAATGTGACG CCTCTTGAAC CAGGGTGGTC AGGCTACGTA ACTCTGGAAT TCTCTAATAC ATCTCCGTTA CCTGTGAAGG TATATGCGTT TGAGGGCGCA TGCCAGTTCC TCTTTTTTTC AGGCAAGGAA CGTTGCAGCA AGTCTTACGA CGAAGCTGGG GGCAAGTATA TGGGGCAAAG TGACGTAACA TTGCCAATTA TTAGT

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