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Seattle Structural Genomics Center for Infectious Disease

AnphA.01019.a: dihydropteroate synthase

Target Characteristics

from organism: Anaplasma phagocytophilum HZ
most recent status: in PDB
center reference id: AnphA.01019.a
is community request: False
associated disease: Human granulocytic anaplasmosis
NIH risk group: 1
is select agent: False
NIH priority
pathogens category:
I

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
AnphA.01019.a.A1.GE27012 Full length( AnphA.01019.a ) 1 270 GE27012
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
AnphA.01019.a.A1.PW27052 Full length( AnphA.01019.a ) 1 270

Structures

image of structure for 6UCZ
6UCZ
Deposited: 9/18/2019
Determination: XRay
Diffraction Image
Clone: AnphA.01019.a.A1.GE27012
Protein: AnphA.01019.a.A1.PW27052

External Resources

Resource Reference ID
OrthoMCL: OG5_128803
PATRIC ID: fig|212042.8.peg.265
RefSeq: YP_504869.1
UniProt: Q2GL82

Enzyme & Pathway Information

Pathway Pathway ID EC Number
superpathway of chorismate metabolism ALL-CHORISMATE-PWY 2.5.1.15
superpathway of tetrahydrofolate biosynthesis and salvage FOLSYN-PWY 2.5.1.15
superpathway of tetrahydrofolate biosynthesis PWY-6612 2.5.1.15
tetrahydrofolate biosynthesis PWY-6614 2.5.1.15

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MQHSAVTTKI VGILNVTPNS FSDGGKFLEA NAAIRHATDL IEHGADVIDV GAESTAPGVS PITQEEEWSR LKEVLPEIIR IAHNAHVEVS IDTRNAKTAE LALKLGVDYI NDQGGLLDPD MPAIAAASSA KIIIMHHFGL PVSQDRSYVG QPEQLLNEII EWLCSRVDTL IAQGVVRERI ILDPGLGFGK LPEYSWYIAK NIGKLKKLGF PVCVGHSRKS MFSLIPVELS ERDVPTAMLS TFLAQQQVDF LRVHDVKLTG ISIKIANLLV

NT Sequence
TTGCAACACT CTGCTGTCAC CACAAAAATT GTTGGTATAT TGAATGTAAC CCCAAATTCG TTCTCCGACG GGGGTAAGTT TTTGGAAGCT AATGCTGCAA TTAGACACGC TACAGATCTA ATAGAGCATG GTGCAGATGT GATTGATGTA GGTGCGGAGT CCACAGCACC TGGCGTATCT CCCATAACAC AGGAAGAAGA ATGGAGCAGG CTGAAGGAGG TTTTACCTGA AATCATACGC ATTGCTCATA ATGCACATGT AGAAGTCAGC ATAGATACAA GAAATGCTAA GACCGCTGAG CTAGCTCTGA AACTGGGTGT AGATTACATA AATGATCAGG GAGGTCTTCT GGATCCTGAT ATGCCGGCAA TCGCGGCAGC AAGTTCTGCC AAAATCATTA TTATGCACCA CTTTGGGCTG CCCGTATCCC AAGACAGAAG CTATGTTGGG CAACCTGAAC AGTTACTAAA TGAAATAATA GAATGGCTGT GCTCGAGAGT TGATACTCTC ATTGCGCAGG GTGTAGTTCG TGAACGCATA ATTTTAGATC CGGGTCTCGG CTTTGGTAAG TTGCCTGAAT ACTCGTGGTA CATTGCTAAA AACATAGGGA AACTAAAAAA ACTTGGCTTT CCAGTCTGCG TGGGGCATTC ACGCAAATCT ATGTTTTCTT TGATACCCGT TGAACTATCA GAAAGAGATG TTCCAACGGC CATGCTGTCC ACGTTTCTTG CACAACAACA GGTAGACTTC CTGCGTGTCC ATGACGTGAA ATTAACTGGA ATATCTATCA AAATAGCAAA CTTGCTTGTG

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