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Seattle Structural Genomics Center for Infectious Disease

AnphA.01110.a: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase (IspE)

Target Characteristics

from organism: Anaplasma phagocytophilum HZ
most recent status: soluble
center reference id: AnphA.01110.a
is community request: False
associated disease: Human granulocytic anaplasmosis
NIH risk group: 1
is select agent: False
NIH priority
pathogens category:
I

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
AnphA.01110.a.A1.GE27021 Full length( AnphA.01110.a ) 1 296 GE27021
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

External Resources

Resource Reference ID
OrthoMCL: OG5_130885
PATRIC ID: fig|212042.8.peg.623
RefSeq: YP_505165.1
UniProt: Q2GKD6

Enzyme & Pathway Information

Pathway Pathway ID EC Number
methylerythritol phosphate pathway I NONMEVIPP-PWY 2.7.1.148
superpathway of geranylgeranyl diphosphate biosynthesis II (via MEP) PWY-5121 2.7.1.148
isoprene biosynthesis I PWY-6270 2.7.1.148
superpathway of ergosterol biosynthesis II PWY-7156 2.7.1.148
taxadiene biosynthesis (engineered) PWY-7392 2.7.1.148
methylerythritol phosphate pathway II PWY-7560 2.7.1.148

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSKYFISAPA KINLFLHIVG KAPCGYHLIE SVFAFVELYD VLEFDIGSRN RGIRFLKPSC INRRDNTIQR AIGHLVRRCS PGTTDNVYVK VLKNIPVSSG LAGGSADAAA AINLLSKLWG INEKETERVA FRVGSDVPVC LESKTAFVAG MGDVVELLED SFLPRHVILV GPKVELSTKS VFDMYNPKAF SPSIGKLPGN SEDWLSLLKE ARNDLTEVSV ELVPEIRIIL DVLGSLDGCC FSRMSGSGAM SFAIFEDENS AELATRYLRR NYPDWFIFKT RIIRSSDQED NNMGNL

NT Sequence
ATGTCGAAGT ATTTTATTAG CGCGCCTGCG AAGATAAACT TGTTTCTCCA TATAGTCGGT AAAGCTCCGT GTGGGTATCA CTTAATAGAG TCTGTCTTTG CATTTGTAGA GTTATACGAT GTTTTAGAGT TTGACATTGG CTCTAGAAAC CGAGGGATAA GGTTTCTCAA ACCTTCGTGT ATTAATAGAC GTGATAACAC TATACAGCGA GCTATTGGAC ATTTGGTGAG GAGATGCTCG CCGGGCACTA CGGATAATGT TTATGTTAAA GTTTTGAAGA ATATTCCTGT ATCGTCTGGA TTGGCAGGCG GGTCAGCAGA TGCCGCTGCT GCTATTAATC TGCTAAGCAA GCTGTGGGGC ATAAATGAAA AAGAAACTGA GAGGGTAGCT TTTAGGGTTG GAAGCGATGT TCCTGTGTGT TTAGAATCTA AAACTGCGTT TGTTGCGGGC ATGGGAGACG TAGTGGAATT GCTAGAAGAC TCATTCTTGC CTAGGCACGT TATTTTGGTA GGGCCCAAAG TGGAATTGAG CACAAAAAGT GTCTTTGACA TGTACAATCC CAAAGCGTTT TCTCCAAGTA TAGGTAAGTT GCCTGGTAAT TCTGAGGATT GGCTTTCTTT ATTGAAGGAA GCTCGTAATG ACTTAACGGA GGTTTCTGTA GAATTGGTAC CGGAGATTCG TATCATATTG GATGTGCTGG GTTCATTAGA TGGGTGTTGC TTTTCCAGAA TGAGTGGAAG TGGGGCTATG AGCTTCGCTA TTTTTGAGGA TGAGAATTCA GCTGAGTTAG CCACTAGGTA TCTGAGGAGA AATTACCCAG ACTGGTTTAT TTTCAAAACT AGGATTATTA GGTCGAGTGA TCAGGAAGAT AATAATATGG GTAATCTT

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