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Seattle Structural Genomics Center for Infectious Disease

AnphA.01136.a: 1-deoxy-D-xylulose 5-phosphate reductoisomerase (IspC)

Target Characteristics

from organism: Anaplasma phagocytophilum HZ
most recent status: purified
center reference id: AnphA.01136.a
is community request: False
associated disease: Human granulocytic anaplasmosis
NIH risk group: 1
is select agent: False
NIH priority
pathogens category:
I

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
AnphA.01136.a.A1.GE27025 Full length( AnphA.01136.a ) 1 385 GE27025
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
AnphA.01136.a.A1.PW26996 Full length( AnphA.01136.a ) 1 385

External Resources

Resource Reference ID
OrthoMCL: OG5_130462
PATRIC ID: fig|212042.8.peg.469
RefSeq: YP_505043.1
UniProt: Q2GKQ8

Enzyme & Pathway Information

Pathway Pathway ID EC Number
methylerythritol phosphate pathway I NONMEVIPP-PWY 1.1.1.267
superpathway of geranylgeranyl diphosphate biosynthesis II (via MEP) PWY-5121 1.1.1.267
isoprene biosynthesis I PWY-6270 1.1.1.267
superpathway of ergosterol biosynthesis II PWY-7156 1.1.1.267
taxadiene biosynthesis (engineered) PWY-7392 1.1.1.267
methylerythritol phosphate pathway II PWY-7560 1.1.1.267

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MKKVSVFGST GFIGKTTVGI LSGNTEDFKV IALVAGSNVS LLAQQAKLLN AEMAVIADDA QYEELKRSLH GSGIRVAAGK EAVLEAAALS VDTAVMAITG IVALSAVMRL IESGVGTIAL ASKESVVCGG VLLRDAACKS GTRIVPVDSE HNAVFRLLSQ GDNPYKITIT ASGGPFLHWS HDQLKSVTIE DALVHPVWKM GKKISVDSAT MMNKALEVLE ASYLFELGYR KIDVVIHPES IVHALAFYQD GTSTALMSLP DMSIPILHAL YWPHRKEVSV REVDLIAYGK LTFIRPDFER FPALKAAFDI LQSSERDVAS IVFNAANEVA VESFLNSEIT FLEIVNIVLH VMNKVPYGKV SSLADIMEYD LLGRCIAREV ISDAS

NT Sequence
GTGAAAAAGG TATCAGTTTT CGGTTCTACA GGATTTATAG GTAAAACTAC TGTAGGTATT TTATCGGGTA ATACAGAAGA TTTTAAGGTT ATTGCGCTTG TAGCTGGTAG TAACGTGAGC TTGTTGGCGC AGCAGGCTAA GTTATTAAAT GCTGAAATGG CGGTTATTGC TGATGATGCT CAATATGAGG AGCTTAAAAG GTCTTTACAT GGTTCAGGTA TAAGGGTTGC TGCTGGTAAG GAGGCTGTGC TTGAAGCGGC TGCCCTTAGT GTAGATACCG CTGTAATGGC TATCACTGGT ATTGTGGCTT TAAGTGCGGT GATGCGGCTG ATAGAAAGTG GTGTAGGTAC TATTGCTTTA GCCAGCAAGG AGAGTGTAGT TTGTGGGGGA GTTCTTCTAA GGGATGCTGC TTGTAAAAGT GGAACTAGGA TTGTTCCGGT GGATTCAGAG CATAATGCGG TTTTTCGTCT ATTATCTCAG GGGGATAATC CCTATAAGAT TACAATTACG GCTTCAGGAG GGCCTTTTCT GCATTGGTCT CATGATCAAT TAAAAAGTGT TACAATAGAA GATGCGCTAG TTCATCCAGT TTGGAAAATG GGTAAGAAAA TCTCTGTGGA TAGTGCAACG ATGATGAATA AAGCTTTGGA AGTATTAGAA GCTAGTTACC TTTTTGAGCT CGGATATAGG AAAATAGATG TTGTGATTCA TCCGGAATCA ATAGTTCATG CTTTGGCGTT TTATCAGGAT GGAACTTCTA CTGCGTTAAT GTCGTTGCCG GATATGAGTA TCCCAATACT TCATGCGTTA TATTGGCCTC ATAGGAAGGA GGTGTCTGTA AGGGAGGTGG ATTTAATTGC GTATGGCAAA TTGACCTTTA TTAGGCCTGA TTTTGAGAGA TTTCCGGCAC TGAAGGCTGC ATTTGATATT TTACAGTCTT CTGAGAGGGA TGTTGCAAGT ATAGTATTTA ATGCTGCAAA TGAAGTTGCG GTGGAGTCAT TTTTAAATTC CGAGATTACT TTTTTAGAGA TAGTTAATAT TGTTTTGCAT GTGATGAACA AGGTTCCTTA TGGAAAAGTC TCTTCTCTAG CAGACATAAT GGAATATGAT TTATTAGGCA GGTGTATAGC TAGAGAGGTT ATTAGCGATG CGTCT

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