NIAID Emerging and Re-emerging Infectious Diseases NIAID Bioinformatics Resource Centers NIAID Structural Genomic Centers Center for Structural Genomics of Infectious Disease
Seattle Structural Genomics Center for Infectious Disease

AnphA.01176.a: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (IspF)

Target Characteristics

from organism: Anaplasma phagocytophilum HZ
most recent status: expressed
center reference id: AnphA.01176.a
is community request: False
associated disease: Human granulocytic anaplasmosis
NIH risk group: 1
is select agent: False
NIH priority
pathogens category:
I

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
AnphA.01176.a.A1.GE27032 Full length( AnphA.01176.a ) 1 157 GE27032
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

External Resources

Resource Reference ID
OrthoMCL: OG5_130616
PATRIC ID: fig|212042.8.peg.1367
RefSeq: YP_505793.1
UniProt: Q2GIK8

Enzyme & Pathway Information

Pathway Pathway ID EC Number
methylerythritol phosphate pathway I NONMEVIPP-PWY 4.6.1.12
superpathway of geranylgeranyl diphosphate biosynthesis II (via MEP) PWY-5121 4.6.1.12
isoprene biosynthesis I PWY-6270 4.6.1.12
superpathway of ergosterol biosynthesis II PWY-7156 4.6.1.12
taxadiene biosynthesis (engineered) PWY-7392 4.6.1.12
methylerythritol phosphate pathway II PWY-7560 4.6.1.12

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MGFDVHRFTE SREEGQYIPI CGIKVAHTQG IVAHSDGDVA LHALTDALLG CMGEGSIGQH FPNSDPQWKN ASSSYFLLEA QKKAAAKSYA ILNFDVTIVC EQPKIMPHVP KMKEFLSKLL DVDVSQMNIK AVTTEKLGFL GRGEGIAAHA VLMCYRV

NT Sequence
ATGGGTTTTG ATGTACATAG ATTTACCGAG TCAAGAGAGG AAGGGCAGTA CATACCCATA TGTGGAATAA AGGTAGCGCA TACACAGGGA ATAGTTGCGC ATTCGGATGG GGATGTTGCA CTTCATGCAC TTACAGATGC ATTATTAGGC TGCATGGGAG AGGGGAGTAT AGGGCAGCAT TTTCCTAATA GTGATCCTCA ATGGAAGAAT GCAAGCTCAT CTTATTTCTT GTTGGAAGCA CAAAAAAAGG CTGCCGCAAA ATCTTATGCG ATACTAAATT TTGACGTGAC TATAGTGTGT GAGCAACCAA AAATAATGCC CCATGTACCT AAAATGAAAG AGTTTCTGTC TAAGCTGTTA GATGTTGATG TATCACAAAT GAACATTAAG GCAGTAACGA CGGAAAAGCT TGGGTTTTTG GGTCGCGGTG AAGGTATTGC AGCACATGCC GTGTTGATGT GTTATAGGGT G

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