NIAID Emerging and Re-emerging Infectious Diseases NIAID Bioinformatics Resource Centers NIAID Structural Genomic Centers Center for Structural Genomics of Infectious Disease
Seattle Structural Genomics Center for Infectious Disease

BaboA.01136.a: 1-deoxy-D-xylulose-5-phosphate reductoisomerase (IspC/dxr)

Target Characteristics

from organism: Babesia bovis T2Bo
most recent status: soluble
center reference id: BaboA.01136.a
is community request: True
associated disease: Babesiosis (atypical)
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
I

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

External Resources

Resource Reference ID
EuPathDB: PiroplasmaDB:BBOV_III010740
OrthoMCL: OG5_130462
RefSeq: XP_001612194.1
UniProt: A7APZ2

Enzyme & Pathway Information

Pathway Pathway ID EC Number
methylerythritol phosphate pathway I NONMEVIPP-PWY 1.1.1.267
superpathway of geranylgeranyl diphosphate biosynthesis II (via MEP) PWY-5121 1.1.1.267
isoprene biosynthesis I PWY-6270 1.1.1.267
superpathway of ergosterol biosynthesis II PWY-7156 1.1.1.267
taxadiene biosynthesis (engineered) PWY-7392 1.1.1.267
methylerythritol phosphate pathway II PWY-7560 1.1.1.267

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MGKTGRAFEY YSGLDWQCVA KVTSSVGSVI KLLKNACPRK VAVIGSTGSI GCQTLDIIRR INATYDEPLF DVVALSANCN IKDLAQQAKE FKPKILNINY GYDELRQNVN NDIDITEGKE GILQLCRNFD YDLLVMGISG CAGIEPTIAA AEAGKSVALA NKESVVSAGS TLRRVLDKSK CELIPIDSEH NAIYQCLVTS PRDLLEHTKE RDPRAMCRIS TNVLNSVKRL IITSSGGPFR DTDKSLMKTL RLKDAIKHPV WSMGAKITID SSTMMNKGLE VIEAHELFGI PYDNIQVVIH KECIVHSMVQ FVDNSVLAQM YNPDMRLPIA YALNWPDRME STLPELDLLK QQLTFTDPDL EKFPCLKLAF EAGKMGGLYT TVLNAANERA NEFLREDAIA HWEIHELVKR AVEEYKHPNI DHPRIEDVME ADSWGKNHVM ESMKNRH

NT Sequence
atgggtaaaa ctggaagagc gtttgaatac tacagcggtc tagactggca atgtgtcgct aaggttacaa gctctgttgg cagcgttatc aaactactga aaaatgcatg cccacgcaag gtggccgtta taggaagcac tggaagcata ggttgccaaa ccctggacat cattcgtcgc attaacgcaa catatgatga gccactcttt gacgttgtgg ctctatcagc caactgcaac attaaagatt tggcgcagca ggcaaaggag ttcaaaccta agatcttgaa tattaactat ggatatgatg aacttcgcca gaacgttaac aatgatatcg acattactga aggtaaagaa ggtatactac aactatgtag gaattttgac tatgatctat tggtcatggg tatatctgga tgtgccggca ttgaaccgac catagcagca gctgaggcag gtaaaagtgt ggctttagct aacaaagagt ctgttgtatc agcaggtagt acactgcgta gagtcctcga taaaagcaag tgtgaactga tacccatcga ttctgaacac aatgctatat accagtgcct tgtgacatct cctagggatc tcttagaaca cacgaaggaa agggatccca gagctatgtg caggatatcg acaaacgttt taaattcggt gaaacgtttg attataacta gtagcggcgg ccctttcagg gataccgata agtccttaat gaaaacactt cgccttaagg atgccataaa acaccctgtg tggagtatgg gtgcgaaaat aactattgat tcatccacaa tgatgaataa aggtttagag gtaattgaag ctcatgagct ttttggaatt ccgtatgata acattcaagt ggtcattcac aaagaatgca ttgtccactc gatggtacaa tttgttgata actcggtttt ggcacaaatg tacaaccccg atatgaggtt acctatcgca tacgctctaa attggcctga taggatggaa tctacgctcc cagaattgga tttgctcaag cagcaactga cattcacgga ccctgattta gaaaagttcc cttgtcttaa gttggctttt gaagccggaa agatgggtgg attgtataca acagttttaa acgcagcaaa tgaacgcgct aatgagtttt tgagggaaga tgcaatagct cattgggaaa tacatgagct ggtgaagcgt gcggtagaag agtacaaaca tccaaacata gaccacccta ggattgagga tgtaatggaa gctgattcat gggggaagaa ccatgttatg gaatctatga agaatagaca ctaa

© 2019 Center for Infectious Disease Research. All rights reserved. Contact ssgcid@cidresearch.org with questions or feedback.