NIAID Emerging and Re-emerging Infectious Diseases NIAID Bioinformatics Resource Centers NIAID Structural Genomic Centers Center for Structural Genomics of Infectious Disease
Seattle Structural Genomics Center for Infectious Disease

BaboA.01620.a: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, putative [Babesia bovis T2Bo] (IspF)

Target Characteristics

from organism: Babesia bovis T2Bo
most recent status: diffraction
center reference id: BaboA.01620.a
is community request: True
associated disease: Babesiosis (atypical)
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
I

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BaboA.01620.a.A2.GE29393 corrected N-term 33 199 GE29393
BaboA.01620.a.B1.GE26932 Full length( BaboA.01620.a ) 1 199 GE26932
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BaboA.01620.a.A2.PW29290 corrected N-term 33 199

External Resources

Resource Reference ID
EuPathDB: PiroplasmaDB:BBOV_IV002810
OrthoMCL: OG5_130616
RefSeq: XP_001609446.1
UniProt: A7AVQ2

Enzyme & Pathway Information

Pathway Pathway ID EC Number
methylerythritol phosphate pathway I NONMEVIPP-PWY 4.6.1.12
superpathway of geranylgeranyl diphosphate biosynthesis II (via MEP) PWY-5121 4.6.1.12
isoprene biosynthesis I PWY-6270 4.6.1.12
superpathway of ergosterol biosynthesis II PWY-7156 4.6.1.12
taxadiene biosynthesis (engineered) PWY-7392 4.6.1.12
methylerythritol phosphate pathway II PWY-7560 4.6.1.12

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MLAFSFRHYT VKTNVVNRNA LGQTRHDASD NSMDKDAYRI GLGYDIHRLV GTGKGGKPFK LGGVLVDDSK IFVVGHSDGD TLLHALADAL LGATGCGDIG DYFSELDSIN KDMDSRIILE SAIKEASLRG YRPTNIDINI ILERVRLGRR LKDAIKKALY DMLGSDVMIN VKAKTNEGLD AIGRGEAVSC QVIAHLKRI

NT Sequence
ATGTTGGCAT TCAGCTTTAG ACACTACACG GTAAAGACTA ATGTTGTAAA TCGCAATGCC CTAGGACAAA CAAGGCACGA TGCTTCAGAC AATTCCATGG ATAAAGACGC TTACAGGATA GGTTTGGGTT ACGACATTCA CCGATTAGTT GGCACTGGTA AAGGTGGCAA GCCTTTCAAG CTTGGTGGCG TATTGGTGGA CGATTCCAAG ATTTTTGTTG TTGGCCATAG CGATGGTGAT ACTTTGCTAC ACGCCTTGGC AGATGCTTTA TTAGGTGCCA CTGGTTGTGG TGATATAGGT GACTATTTTT CCGAGCTAGA TTCAATAAAC AAAGATATGG ACTCTCGCAT AATATTGGAA TCTGCAATCA AGGAAGCATC ATTACGTGGT TACAGACCAA CGAACATTGA TATAAACATA ATACTAGAGC GTGTGCGATT AGGAAGAAGA TTAAAAGATG CCATAAAAAA GGCACTGTAT GATATGCTGG GCTCCGACGT TATGATTAAT GTAAAGGCGA AGACTAACGA AGGACTTGAT GCTATAGGCA GAGGTGAAGC CGTTTCGTGC CAAGTAATAG CCCATCTAAA ACGTATA

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