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Seattle Structural Genomics Center for Infectious Disease

BaboA.17239.a: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase (IspH/LytB) (IspG/H)

Target Characteristics

from organism: Babesia bovis T2Bo
most recent status: crystallized
center reference id: BaboA.17239.a
is community request: True
associated disease: Babesiosis (atypical)
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
I

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BaboA.17239.a.D16.PD00200 Full length( BaboA.17239.a ) 75 397
BaboA.17239.a.D15.PD00201 Full length( BaboA.17239.a ) 59 397
BaboA.17239.a.D14.PD00208 Full length( BaboA.17239.a ) 75 419

External Resources

Resource Reference ID
EuPathDB: PiroplasmaDB:BBOV_III001660
OrthoMCL: OG5_130373
RefSeq: XP_001611301.1
UniProt: A7AME9

Enzyme & Pathway Information

Pathway Pathway ID EC Number
1.17.1.2

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MLKLLFLILL SSFTQCLVIQ HIGYIGQWPR DVATANSYFK GRYRSNTTSN QVLLATPSSD VCDNNGAHIN DSASTPIQDN VEKTVFLLEP RGFCAGVRRA IETVEEAVRI FGPPIYVKHE IVHNEFVCNT LKKKGVIFIE DIETVPEGSI LVLSAHGVPP SVHEMVKKRN LVEIDASCPL VNKVHVYVRK KAEEGYKIIL IGHKSHVETI GTLGEAPDVT TVVETVDDVD RLEYSRDTPL FYATQTTLSV DDCKIIKDRL LERFPWIETI PSGSICYATT NRQFAVRDAC NFCDLVLVVG SSLSSNANRL VDTANLRNVR AHLIPNADAI TEELIGDARK IALSASASTP DELTADVVKK LAVPPYNYNI EIYHSCDERV PKWRLPRNLE LYIKEHDAKM QANLESSLVS PPVSPGVST

NT Sequence
ATGCTAAAAT TATTATTTTT AATACTGCTT TCATCATTTA CACAGTGTCT AGTTATCCAA CATATAGGTT ACATAGGTCA ATGGCCCCGC GACGTTGCTA CAGCAAATAG CTACTTTAAA GGACGATACA GAAGCAATAC CACATCTAAT CAGGTGTTAT TGGCAACGCC ATCGAGTGAT GTGTGCGATA ACAATGGCGC GCATATAAAT GATTCCGCCA GTACACCAAT ACAGGATAAT GTAGAGAAGA CGGTGTTTTT ATTAGAGCCA CGAGGCTTTT GTGCTGGAGT TCGCCGTGCA ATAGAGACTG TAGAAGAGGC TGTTAGAATA TTTGGTCCTC CTATTTACGT AAAACATGAG ATTGTTCACA ACGAGTTTGT TTGCAATACT TTGAAGAAAA AAGGGGTAAT ATTTATTGAA GACATTGAAA CAGTTCCTGA AGGAAGTATA TTAGTTTTAT CTGCCCATGG AGTGCCACCG TCAGTTCACG AGATGGTTAA GAAACGCAAT CTCGTTGAGA TTGATGCCTC ATGCCCACTT GTGAACAAAG TCCATGTCTA CGTAAGGAAG AAGGCAGAGG AAGGGTACAA AATTATATTG ATAGGGCACA AATCACATGT TGAAACCATT GGCACATTGG GCGAAGCTCC CGATGTCACT ACAGTGGTGG AAACTGTGGA TGACGTGGAC CGTTTAGAAT ATAGTCGGGA TACTCCTCTA TTTTATGCAA CACAGACGAC GCTTAGTGTT GATGATTGCA AGATAATAAA GGACCGTTTG CTGGAGCGTT TCCCCTGGAT TGAGACAATT CCTAGTGGTT CCATTTGCTA TGCTACGACC AACAGACAAT TTGCTGTTCG TGATGCGTGC AATTTTTGCG ATTTGGTATT AGTTGTTGGC AGCAGTTTGT CTTCAAATGC GAATCGTTTG GTTGACACCG CTAATCTACG CAACGTACGT GCCCATTTAA TACCGAATGC TGATGCCATC ACCGAAGAGT TGATTGGTGA TGCTCGTAAA ATCGCATTGT CCGCTTCCGC TTCAACTCCA GATGAGCTAA CTGCGGATGT AGTTAAGAAG TTGGCCGTTC CACCATACAA TTACAATATT GAGATCTATC ATAGTTGCGA TGAGCGTGTA CCAAAGTGGA GATTACCAAG AAACTTGGAA CTCTACATCA AGGAACATGA TGCAAAGATG CAGGCAAATC TAGAATCATC ACTAGTGTCG CCCCCTGTAA GCCCGGGTGT CAGCACA

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