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Seattle Structural Genomics Center for Infectious Disease

BaboA.17240.a: (E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase (IspG/GcpE) (IspG/H)

Target Characteristics

from organism: Babesia bovis T2Bo
most recent status: cloned
center reference id: BaboA.17240.a
is community request: True
associated disease: Babesiosis (atypical)
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
I

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

External Resources

Resource Reference ID
EuPathDB: PiroplasmaDB:BBOV_II006930
OrthoMCL: OG5_130276
RefSeq: XP_001610211.1
UniProt: A7AUN2

Enzyme & Pathway Information

Pathway Pathway ID EC Number
1.17.4.3
methylerythritol phosphate pathway II PWY-7560 1.17.7.1

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MAKWYFIFLS IFEVIRPTEG FRLRHDPFAY VHGNKTTQQT EGAAGGPLNH GSLPNTLQAL SSDRLPAGIA PLCIPNCNTA SNNVYCESVT ERIRFPTREV RIGNVTIGGN RPIALQTMTS SDTYDIDATV KQIITCHQYG ASLVRLAVQS PREAKASAVI KEKLLSQGCN VPLVADIHYS PKVALMAAEI FDKVRVNPGN YVDGRKDWDE KIYKTEEEFR EGTKLIEERL TPLIEKCKKL KRAIRIGTNH GSLSSRIMSY YGDSPMGMVM SAMEFAEICV KNDFHDIVFS MKSSNSFVMV HAYRLLVNEL YKRGWNYPIH LGVTEAGSVD DGRIKSAMGI GSLLLDGIGD TIRLSLTEDP WLELLPGRKL LQYVDGITKK DGSSTKPRIR SDFRDFNNIS RRTIDYGTSL LDFDDGRKTI LNRDGSVGCL ITDEDLSDPL TLYKALNVVM KDGLPQRCLK SVDFIYMENT PLFHDFNGQR VLKELIEGGF QVLAPVDQLQ EQPIKFAIGV VDLMKLEDFQ RSQSSPNHPY AETRIDFTDK IANLAIRITG NEPDSYLEKL CSIERGISSK ALGSGVPRMI ILDIDSKLNH VETVRRIFGI LVKNGSKLPV VHMVDATECF DHEEVVINVS TALSTHLIDK LGEGVMIKSR LPLAESNDIA LSILQAARMR SFKTEFISCP SCGRTLFDIQ KTTESIKKRV GHLPGVSIAI MGCIVNGIGE MADADFGYVG GAPHKVDLYV KKELVERNVP DVEACDRLIE LIKKHGKWVE PE

NT Sequence
ATGGCTAAAT GGTACTTTAT ATTTTTATCA ATTTTTGAGG TCATCCGTCC AACGGAAGGC TTCAGATTAA GACACGATCC ATTTGCCTAT GTACACGGCA ATAAGACAAC CCAGCAAACT GAAGGTGCAG CTGGTGGTCC ACTAAACCAT GGAAGTTTGC CAAATACCCT CCAGGCGTTA TCGTCTGATA GGTTACCTGC AGGTATAGCT CCATTGTGTA TACCAAATTG CAATACAGCA TCGAACAATG TCTATTGTGA ATCCGTAACT GAGCGCATAC GGTTCCCTAC AAGGGAGGTG CGCATAGGAA ACGTTACTAT AGGTGGCAAT AGACCTATAG CTCTCCAAAC TATGACATCA TCCGATACCT ATGATATAGA TGCCACCGTT AAGCAGATAA TAACATGCCA TCAGTATGGT GCATCTCTAG TTCGCCTTGC CGTACAGTCA CCACGGGAGG CTAAAGCCTC TGCGGTAATA AAGGAGAAGC TTCTGTCTCA GGGTTGCAAT GTACCACTTG TAGCCGATAT ACATTACTCC CCAAAGGTTG CTTTGATGGC AGCTGAAATT TTCGATAAGG TTCGGGTTAA TCCTGGCAAC TATGTCGATG GTCGTAAGGA TTGGGATGAA AAGATATACA AGACGGAAGA GGAATTCCGG GAGGGGACTA AATTGATAGA GGAGCGGTTG ACGCCACTTA TTGAAAAGTG CAAGAAGTTG AAGCGTGCAA TCCGTATTGG TACTAACCAC GGTTCCTTAT CATCTCGTAT AATGAGTTAC TATGGCGATT CTCCTATGGG AATGGTTATG TCCGCCATGG AATTTGCTGA AATTTGTGTG AAGAACGACT TCCACGATAT TGTATTTTCT ATGAAGTCTT CTAATTCCTT TGTTATGGTA CATGCTTACA GACTTTTAGT AAATGAGCTA TACAAGCGTG GTTGGAACTA TCCCATTCAT CTGGGTGTTA CGGAAGCCGG TTCAGTTGAC GATGGTCGAA TAAAGAGTGC CATGGGTATT GGTTCATTGC TTTTGGATGG TATTGGTGAT ACCATCCGTT TATCATTGAC TGAGGATCCG TGGTTGGAGC TCCTTCCTGG CCGCAAGCTA CTGCAATATG TAGATGGTAT AACTAAAAAG GATGGATCAA GCACAAAACC TCGAATTAGG TCGGATTTCC GTGATTTCAA CAACATATCA CGCCGCACTA TAGATTACGG CACATCACTA TTGGATTTTG ATGATGGTAG GAAAACCATA TTGAATCGTG ACGGTTCAGT TGGTTGCTTG ATCACGGATG AAGATTTATC TGACCCGCTC ACATTATACA AAGCGTTGAA TGTTGTAATG AAGGACGGTT TACCTCAGCG GTGCCTGAAA TCAGTAGACT TTATTTATAT GGAAAACACA CCATTATTTC ACGACTTTAA TGGCCAGAGG GTACTAAAAG AGCTGATAGA GGGTGGTTTT CAGGTACTAG CTCCAGTTGA CCAGTTGCAA GAGCAACCCA TTAAATTTGC TATTGGTGTG GTCGACCTAA TGAAATTAGA GGATTTCCAG CGGTCTCAAT CCTCTCCCAA CCATCCCTAT GCCGAAACAC GTATTGACTT CACGGACAAG ATAGCCAATT TGGCGATAAG GATAACGGGG AATGAGCCAG ACAGTTACCT AGAGAAGCTA TGTAGCATTG AGCGGGGCAT ATCAAGTAAA GCCCTTGGTT CTGGAGTGCC CCGGATGATC ATATTAGACA TTGATTCAAA ATTGAACCAC GTTGAGACTG TGCGTCGTAT ATTTGGAATT TTGGTTAAGA ACGGTTCCAA GCTTCCAGTG GTGCACATGG TGGATGCCAC TGAGTGTTTC GATCACGAGG AGGTTGTCAT CAACGTATCG ACTGCTTTAT CGACCCATCT GATTGATAAA TTGGGGGAGG GTGTGATGAT AAAATCACGC CTACCTCTTG CGGAGAGTAA CGACATTGCT TTGAGTATTT TACAGGCTGC TCGTATGAGA AGCTTCAAGA CAGAATTCAT TTCATGTCCT TCTTGTGGTA GGACACTGTT TGATATCCAG AAAACGACGG AATCCATTAA AAAACGGGTG GGGCATCTAC CAGGGGTCAG TATTGCCATC ATGGGTTGCA TTGTCAATGG TATCGGTGAA ATGGCTGATG CTGATTTCGG TTATGTTGGC GGCGCGCCTC ATAAGGTTGA CTTATATGTG AAAAAGGAGC TGGTTGAGCG AAACGTGCCA GATGTTGAAG CATGTGACCG TTTGATTGAA TTGATTAAGA AGCACGGCAA ATGGGTTGAA CCTGAA

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