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Seattle Structural Genomics Center for Infectious Disease

BaboA.17241.a: 1-deoxy-D-xylulose-5-phosphate synthase (DOXP/dxs/dxp)

Target Characteristics

from organism: Babesia bovis T2Bo
most recent status: soluble
center reference id: BaboA.17241.a
is community request: True
associated disease: Babesiosis (atypical)
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
I

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

External Resources

Resource Reference ID
EuPathDB: PiroplasmaDB:BBOV_III002600
OrthoMCL: OG5_129068
RefSeq: XP_001611393.1
UniProt: A7AMP1

Enzyme & Pathway Information

Pathway Pathway ID EC Number
methylerythritol phosphate pathway I NONMEVIPP-PWY 2.2.1.7
superpathway of pyridoxal 5'-phosphate biosynthesis and salvage PWY0-845 2.2.1.7
superpathway of geranylgeranyl diphosphate biosynthesis II (via MEP) PWY-5121 2.2.1.7
isoprene biosynthesis I PWY-6270 2.2.1.7
thiazole biosynthesis II (aerobic bacteria) PWY-6891 2.2.1.7
thiazole biosynthesis I (facultative anaerobic bacteria) PWY-6892 2.2.1.7
superpathway of thiamine diphosphate biosynthesis II PWY-6895 2.2.1.7
superpathway of ergosterol biosynthesis II PWY-7156 2.2.1.7
taxadiene biosynthesis (engineered) PWY-7392 2.2.1.7
methylerythritol phosphate pathway II PWY-7560 2.2.1.7
pyridoxal 5'-phosphate biosynthesis I PYRIDOXSYN-PWY 2.2.1.7
superpathway of thiamine diphosphate biosynthesis I THISYN-PWY 2.2.1.7

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MVLMLPLVLK YARTSKFLLP MKKGFIATKT PRKCKSPDVQ WIQLGVHSTS KVGIDLLDPE DRGECHLDVN SPEDVKRIPE SQLNDLCKEL RRCFMLNAEA VGGHYSSSLG VVELTVALHR VFDSPKDRIV WDIGHQGYIH KMLTGRLHKM QTMRQCGGLS GFLRRYESPH DLFGAGHSST SIGALQGIYE GDVITGQSSN RSYVCVIGDG SLTGGMAMEA LNYTCTIKSP LLIIYNDNEQ SSLPTGMPAK NGTGPVVPYF MVEGSRKPAI SGHDAIAQCE ALRHKNDDMP LFIGPIDGHN IEALLDVLAY LKEELSANSE DGIKRPVVLH VKTIKGMGCE KALQSPSRLH SLKVATGPKI GTEATKTFSE IFTESLIDLA EKDQTVLAIT AGMPGSTGVG KMGMKFPNRT FDVGIAEQHA VTFAAGTTIS GAKPFCCIYS TFMQRALDQV IHDVSLQHLP VRFVLDRAGY VGGDGASHHG IYDIIYLRMM YNMLLMAPSN GIELKMMMQI AYNTDKQPSA IRYPNGNVAS HDELTRLLKY TPGEIEDPAS MILPNGKLEA RMVRRGKSGV AVLAFGPIVI DILKAVDAID LDATVVDMRF LNPMDTDMLN YILQAHHTVF TAEDGVEGGF GSAVLEYFAK RPERADVMCI AYPKEFMHHG SIAEQKRLAK MDVEGLAERM RQFLAS

NT Sequence
ATGGTGCTGA TGTTACCCCT TGTTTTAAAG TATGCCAGGA CTTCGAAATT TCTATTACCA ATGAAAAAGG GGTTTATCGC AACTAAAACA CCGCGAAAAT GTAAATCGCC GGACGTACAA TGGATTCAAT TGGGAGTGCA TAGTACGTCT AAGGTCGGTA TAGACCTACT GGACCCGGAA GACAGGGGTG AATGCCATTT AGACGTGAAT TCACCCGAGG ATGTTAAAAG GATACCGGAA AGCCAATTAA ATGACCTTTG CAAGGAACTT AGACGCTGTT TCATGCTTAA CGCTGAGGCA GTGGGTGGTC ATTACTCCAG CTCCCTGGGA GTTGTGGAGT TGACTGTAGC GCTGCACCGT GTCTTCGACT CTCCCAAAGA CAGGATAGTC TGGGACATTG GTCACCAGGG GTACATACAC AAGATGCTCA CTGGGAGGTT ACATAAGATG CAGACCATGC GTCAGTGTGG TGGTCTATCA GGATTCCTCC GTAGGTACGA GAGTCCTCAC GACCTTTTTG GTGCAGGGCA CTCGTCCACT TCCATCGGTG CCCTGCAAGG CATCTATGAG GGTGATGTCA TTACTGGGCA AAGCTCAAAC AGATCCTATG TATGTGTAAT CGGTGACGGT AGCTTAACTG GTGGCATGGC CATGGAGGCC TTGAACTACA CTTGCACCAT CAAGTCGCCC TTGCTCATTA TATACAACGA TAATGAGCAG AGCTCACTGC CAACGGGAAT GCCAGCTAAA AACGGCACCG GTCCTGTAGT ACCGTACTTC ATGGTTGAGG GTTCAAGGAA GCCGGCTATA TCCGGGCACG ACGCCATCGC GCAATGCGAG GCGCTACGAC ACAAAAACGA TGATATGCCG CTGTTCATAG GCCCTATTGA TGGGCATAAT ATCGAGGCCC TGTTAGACGT GCTGGCATAT CTAAAGGAAG AACTCAGTGC CAATAGCGAA GATGGCATTA AAAGGCCAGT GGTACTACAC GTGAAAACCA TCAAAGGCAT GGGATGCGAA AAAGCGCTGC AATCGCCATC TAGACTGCAT TCATTAAAGG TTGCGACAGG CCCAAAGATA GGCACTGAGG CAACTAAAAC ATTTTCAGAG ATATTCACGG AATCGTTAAT TGACCTTGCT GAAAAGGATC AAACCGTGCT AGCGATAACC GCTGGCATGC CAGGTTCAAC AGGCGTGGGT AAAATGGGTA TGAAATTCCC CAATCGCACT TTTGATGTAG GTATTGCCGA ACAACACGCT GTTACCTTCG CGGCGGGTAC AACCATCAGC GGTGCAAAGC CCTTCTGCTG CATATACTCC ACGTTCATGC AGAGAGCATT GGATCAGGTT ATACACGACG TATCGCTACA ACACCTGCCG GTAAGGTTCG TCCTGGATCG TGCTGGGTAC GTTGGGGGTG ACGGCGCATC ACACCACGGC ATATACGATA TAATATACCT GAGGATGATG TACAACATGC TACTCATGGC ACCCAGCAAC GGTATAGAGT TGAAGATGAT GATGCAAATT GCGTACAACA CAGATAAACA ACCGTCGGCA ATAAGATACC CAAACGGAAA TGTAGCTTCA CATGATGAAT TGACAAGACT CTTGAAGTAC ACCCCGGGTG AAATAGAGGA CCCCGCGTCC ATGATCTTAC CAAACGGAAA GCTAGAAGCG CGCATGGTAC GTCGAGGCAA GAGCGGGGTG GCTGTATTGG CATTCGGTCC CATAGTCATA GATATCCTAA AGGCCGTGGA TGCCATTGAC CTCGACGCCA CGGTAGTGGA TATGCGATTC CTTAACCCAA TGGATACCGA TATGCTCAAC TACATCCTCC AGGCACACCA TACGGTATTT ACCGCGGAGG ACGGCGTGGA AGGTGGCTTC GGCTCCGCTG TACTTGAGTA CTTTGCCAAA AGGCCTGAAC GTGCTGATGT CATGTGCATT GCGTATCCTA AGGAATTCAT GCATCACGGT AGCATTGCAG AGCAGAAACG ATTGGCCAAA ATGGACGTCG AAGGCTTAGC TGAACGTATG AGGCAGTTCC TGGCGTCA

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