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Seattle Structural Genomics Center for Infectious Disease

BaboA.17242.a: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (IspD/YgbP)

Target Characteristics

from organism: Babesia bovis T2Bo
most recent status: purified
center reference id: BaboA.17242.a
is community request: False
associated disease: Babesiosis (atypical)
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
I

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BaboA.17242.a.D13.PD00206 Full length( BaboA.17242.a ) 60 421

External Resources

Resource Reference ID
EuPathDB: PiroplasmaDB:BBOV_III003490
OrthoMCL: OG5_129829
RefSeq: XP_001611481.1
UniProt: A7AMX9

Enzyme & Pathway Information

Pathway Pathway ID EC Number
methylerythritol phosphate pathway I NONMEVIPP-PWY 2.7.7.60
superpathway of geranylgeranyl diphosphate biosynthesis II (via MEP) PWY-5121 2.7.7.60
isoprene biosynthesis I PWY-6270 2.7.7.60
superpathway of ergosterol biosynthesis II PWY-7156 2.7.7.60
taxadiene biosynthesis (engineered) PWY-7392 2.7.7.60
methylerythritol phosphate pathway II PWY-7560 2.7.7.60

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MEYILLHFTE DKEGCLMPVS ALYFLAVYES TFGTPPFHGT KAIPRGNPLF AHNNDLGRCQ KGASAILVCG GVGQRINDVF DNLDSSNANV TILDNCPRAK QFILVHGVPI FIYSFAEFVR SSLVSEVTIA TKPEWHLKVL ELVDCYTQKV PSNEAFNPED ISNRIENPLH KDYIIHVNGR SDSGYMIPRE ASIYPADSAR IEEYRLHLSR YSFVLFDLDS QRCVLSTSSL WPEALSIACS GSPGRYKLVK FCLSGDTRGS TVYNSLTGQN VLGAEFPVVT SSDGIVLVHD AARPMLRRVD MGHLIASARR YGGAIPAIGV VDTIKVGEST GDVNFVFDTP VRSSLFAVQT PQAFVFSVLR TAYEKAMESG TMSMLTDDSS FVERLGTHRV CFVPGHRMNI KLTTSYDLPI CSSYLKEIYF P

NT Sequence
ATGGAATATA TCCTTCTACA TTTCACGGAA GACAAGGAAG GTTGCCTTAT GCCGGTATCG GCGTTATATT TCTTGGCGGT ATATGAATCC ACATTTGGTA CACCTCCGTT CCATGGGACT AAAGCAATTC CTCGTGGCAA TCCATTGTTT GCCCACAATA ACGATCTAGG AAGGTGCCAA AAGGGTGCTT CTGCGATATT GGTTTGCGGT GGTGTTGGCC AACGTATCAA TGATGTCTTT GACAATTTGG ACTCCAGTAA TGCTAACGTT ACTATATTAG ACAACTGCCC ACGGGCTAAA CAGTTCATCC TGGTTCACGG AGTTCCCATT TTTATCTATT CATTTGCTGA GTTTGTAAGA TCATCGTTAG TCAGTGAGGT CACTATAGCT ACAAAGCCTG AATGGCATTT GAAGGTGCTG GAGCTCGTTG ATTGTTACAC TCAGAAGGTT CCTTCTAATG AAGCCTTTAA TCCCGAGGAC ATATCAAATC GCATTGAGAA TCCGTTGCAC AAGGACTACA TAATTCACGT TAATGGCCGT AGCGATTCTG GTTACATGAT TCCTAGGGAG GCTAGTATTT ACCCTGCTGA CAGTGCTAGG ATTGAGGAGT ATCGTTTACA TTTATCGCGG TATTCATTTG TACTATTCGA TCTGGATTCT CAACGTTGTG TTTTGTCTAC ATCATCGCTA TGGCCCGAGG CACTATCTAT AGCTTGCAGT GGTTCCCCGG GTAGATATAA GCTTGTAAAG TTCTGTTTAA GTGGTGACAC TCGTGGTTCA ACTGTGTACA ACTCTCTTAC TGGTCAGAAC GTATTGGGTG CAGAATTCCC AGTGGTTACT AGTTCTGACG GCATCGTATT GGTCCACGAT GCGGCGAGAC CAATGTTACG TCGTGTTGAT ATGGGCCACC TCATAGCGTC TGCTCGTAGG TATGGTGGTG CCATACCGGC TATAGGTGTT GTTGATACTA TAAAAGTTGG TGAAAGCACG GGTGATGTTA ACTTTGTATT TGATACACCG GTTCGGTCAT CACTATTCGC TGTGCAGACT CCGCAGGCTT TTGTTTTTTC TGTGCTCAGG ACAGCCTATG AGAAGGCTAT GGAGTCTGGT ACTATGTCTA TGTTGACTGA CGATTCCAGT TTCGTTGAGC GGCTTGGCAC GCATCGCGTA TGTTTCGTTC CTGGCCATCG CATGAACATT AAGTTGACTA CTAGTTATGA TTTGCCTATA TGCAGCAGTT ATTTGAAGGA GATATATTTT CCG

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