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Seattle Structural Genomics Center for Infectious Disease

BaheA.00264.a: Mutator mutT protein

Target Characteristics

from organism: Bartonella henselae str. Houston-1
most recent status: in PDB
center reference id: BaheA.00264.a
is community request: False
associated disease: Bacillary angiomatosis
NIH risk group: 3
is select agent: False
NIH priority
pathogens category:
I

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BaheA.00264.a.A1.GE25705 Full length( BaheA.00264.a ) 1 137 GE25705
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BaheA.00264.a.A1.PS00131 Full length( BaheA.00264.a ) 1 137

Structures

image of structure for 3HHJ
3HHJ
Deposited: 5/15/2009
Determination: XRay
Diffraction Image
Clone: BaheA.00264.a.A1.GE25705
Protein: BaheA.00264.a.A1.PS00131

Publications by SSGCID

Structure of a Nudix hydrolase (MutT) in the Mg(2+)-bound state from Bartonella henselae, the bacterium responsible for cat scratch fever.
Abendroth J, Arakaki TL, Buchko GW, Edwards TE, Hewitt SN, Law L, Myler PJ, Napuli AJ, Staker BL, Stewart LJ, Van Voorhis WC
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. - 2011
volume 67, issue Pt 9, pages 1078-83
PMID: 21904053; PMCID: PMC3169405
PDB: 3HHJ

Citations by Others

The evolution of function within the Nudix homology clan
JR Srouji, A Xu, A Park, JF Kirsch- Proteins: Structure,, 2017 - Wiley Online Library
cited by: 4 others
PDB: 3HHJ
Insights into substrate recognition by the< i> Escherichia coli Orf135 protein through its solution structure
K Kawasaki, T Kanaba, M Yoneyama? - Biochemical and Biophysical Research Communications, 2012 - Elsevier
cited by: 3 others
PDB: 3HHJ
Structural and dynamic features of the MutT protein in the recognition of nucleotides with the mutagenic 8-oxoguanine base
T Nakamura, S Meshitsuka, S Kitagawa, N Abe? - Journal of Biological Chemistry, 2010 - ASBMB
cited by: 22 others
PDB: 3HHJ

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
OrthoMCL: OG5_133472
PATRIC ID: fig|283166.5.peg.231
RefSeq: YP_033055.1
UniProt: A0A0H3LW43

Enzyme & Pathway Information

Pathway Pathway ID EC Number
oxidized GTP and dGTP detoxification PWY-6502 3.6.1.55

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MPIKSSLLIV VACALLDQDN RVLLTQRPEG KSLAGLWEFP GGKVEQGETP EASLIRELEE ELGVHVQADN LFPLTFASHG YETFHLLMPL YFCSHYKGVA QGREGQNLKW IFINDLDKYP MPEADKPLVQ VLKNFFI

NT Sequence
ATGCCTATAA AAAGTTCACT TCTTATTGTT GTTGCATGCG CATTATTAGA TCAAGATAAT CGTGTTTTGT TGACACAACG TCCTGAAGGA AAATCACTGG CTGGTTTGTG GGAGTTTCCT GGTGGAAAGG TTGAGCAAGG TGAAACTCCG GAAGCATCGT TAATTCGTGA ACTAGAAGAA GAACTTGGTG TTCACGTTCA GGCAGATAAT TTATTCCCCT TAACATTTGC GAGCCATGGC TACGAAACAT TTCATCTTTT AATGCCATTG TATTTTTGCT CCCATTATAA GGGGGTTGCA CAAGGACGAG AAGGACAAAA TTTAAAATGG ATTTTTATTA ACGATCTTGA TAAATATCCT ATGCCTGAAG CTGATAAGCC ATTAGTTCAG GTATTAAAAA ATTTCTTTAT T

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