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Seattle Structural Genomics Center for Infectious Disease

BesaB.18655.a: S protein

Target Characteristics

from organism: Betacoronavirus SARS coronavirus ZJ01
most recent status: in PDB
center reference id: BesaB.18655.a
is community request: False
associated disease:
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

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Structures

image of structure for 6NB6
6NB6
Deposited: 12/6/2018
Determination: CryoEM
Clone: BesaB.18655.a.MG1.GE42877
Protein: BesaB.18655.a.MG1.PE00004
image of structure for 6NB7
6NB7
Deposited: 12/6/2018
Determination: CryoEM
Clone: BesaB.18655.a.MG1.GE42877
Protein: BesaB.18655.a.MG1.PE00004

Publications by SSGCID

Unexpected receptor functional mimicry elucidates activation of coronavirus fusion
Tortorici MA, Snijder J, Walls AC, Rey FA, Veesler D, Xiong X, Park YJ, Quisp J, Cameroni E, Gopal R, Dai M, Lanzavecchia A, Zambon M, Corti D
Cell - 2019
volume 176, issue 5, pages 1026-1039
PMID: 30712865; PMCID: PMC6751136
PDB: 6NB3, 6NB4, 6NB5, 6NB6, 6NB7, 6NB8

Citations by Others

Molecular mechanism for antibody-dependent enhancement of coronavirus entry
Y Wan, J Shang, S Sun, W Tai, J Chen, Q Geng- Journal of, 2019 - Am Soc Microbiol
PDB: 6NB7

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
UniProt: Q6WGP3
ViPR: link

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MFIFLLFLTL TSGSDLDRCT TFDDVQAPNY TQHTSSMRGV YYPDEIFRSD TLYLTQDLFL PFYSNVTGFH TINHTFGNPV IPFKDGIYFA ATEKSNVVRG WVFGSTMNNK SQSVIIINNS TNVVIRACNF ELCDNPFFAV SKPMGTQTHT MIFDNAFNCT FEYISDAFSL DVSEKSGNFK HLREFVFKNK DGFLYVYKGY QPIDVVRDLP SGFNTLKPIF KLPLGINITN FRAILTAFSP AQDIWGTSAA AYFVGYLKPT TFMLKYDENG TITDAVDCSQ NPLAELKCSV KSFEIDKGIY QTSNFRVVPS GDVVRFPNIT NLCPFGEVFN ATKFPSVYAW ERKKISNCVA DYSVLYNSTF FSTFKCYGVS ATKLNDLCFS NVYADSFVVK GDDVRQIAPG QTGVIADYNY KLPDDFMGCV LAWNTRNIDA TSTGNYNYKY RYLRHGKLRP FERDISNVPF SPDGKPCTPP ALNCYWPLND YGFYTTTGIG YQPYRVVVLS FELLNAPATV CGPKLSTDLI KNQCVNFNFN GLTGTGVLTP SSKRFQPFQQ FGRDVSDFTD SVRDPKTSEI LDISPCSFGG VSVITPGTNA SSEVAVLYQD VNCTDVSTAI HADQLTPAWR IYSTGNNVFQ TQAGCLIGAE HVDTSYECDI PIGAGICASY HTVSLLRSTS QKSIVAYTMS LGADSSIAYS NNTIAIPTNF SISITTEVMP VSMAKTSVDC NMYICGDSTE CANLLLQYGS FCTQLNRALS GIAAEQDRNT REVFAQVKQM YKTPTLKYFG GFNFSQILPD PLKPTKRSFI EDLLFNKVTL ADAGFMKQYG ECLGDINARD LICAQKFNGL TVLPPLLTDD MIAAYTAALV SGTATAGWTF GAGAALQIPF AMQMAYRFNG IGVTQNVLYE NQKQIANQFN KAISQIQESL TTTSTALGKL QDVVNQNAQA LNTLVKQLSS NFGAISSVLN DILSRLDKVE AEVQIDRLIT GRLQSLQTYV TQQLIRAAEI RASANLAATK MSECVLGQSK RVDFCGKGYH LMSFPQAAPH GVVFLHVTYV PSQERNFTTA PAICHEGKAY FPREGVFVFN GTSWFITQRN FFSPQIITTD NTFVSGNCDV VIGIINNTVY DPLQPELDSF KEELDKYFKN HTSPDVDLGD ISGINASVVN IQKEIDRLNE VAKNLNESLI DLQELGKYEQ YIKWPWYVWL GFIAGLIAIV MVTILLCCMT SCCSCLKGAC SCGSCCKFDE DDSEPVLKGV KLHYT

NT Sequence
ATGTTTATTT TCTTATTATT TCTTACTCTC ACTAGTGGTA GTGACCTTGA CCGGTGCACC ACTTTTGATG ATGTTCAAGC TCCTAATTAC ACTCAACATA CTTCATCTAT GAGGGGGGTT TACTATCCTG ATGAAATTTT TAGATCAGAC ACTCTTTATT TAACTCAGGA TTTATTTCTT CCATTTTATT CTAATGTTAC AGGGTTTCAT ACTATTAATC ATACGTTTGG CAACCCTGTC ATACCTTTTA AGGATGGTAT TTATTTTGCT GCCACAGAGA AATCAAATGT TGTCCGTGGT TGGGTTTTTG GTTCTACCAT GAACAACAAG TCACAGTCGG TGATTATTAT TAACAATTCT ACTAATGTTG TTATACGAGC ATGTAACTTT GAATTGTGTG ACAACCCTTT CTTTGCTGTT TCTAAACCCA TGGGTACACA GACACATACT ATGATATTCG ATAATGCATT TAATTGCACT TTCGAGTACA TATCTGATGC CTTTTCGCTT GATGTTTCAG AAAAGTCAGG TAATTTTAAA CACTTACGAG AGTTTGTGTT TAAAAATAAA GATGGGTTTC TCTATGTTTA TAAGGGCTAT CAACCTATAG ATGTAGTTCG TGATCTACCT TCTGGTTTTA ACACTTTGAA ACCTATTTTT AAGTTGCCTC TTGGTATTAA CATTACAAAT TTTAGAGCCA TTCTTACAGC CTTTTCACCT GCTCAAGACA TTTGGGGCAC GTCAGCTGCA GCCTATTTTG TTGGCTATTT AAAGCCAACT ACATTTATGC TCAAGTATGA TGAAAATGGT ACAATCACAG ATGCTGTTGA TTGTTCTCAA AATCCACTTG CTGAACTCAA ATGCTCTGTT AAGAGCTTTG AGATTGACAA AGGAATTTAC CAGACCTCTA ATTTCAGGGT TGTTCCCTCA GGAGATGTTG TGAGATTCCC TAATATTACA AACTTGTGTC CTTTTGGAGA GGTTTTTAAT GCTACTAAAT TCCCTTCTGT CTATGCATGG GAGAGAAAAA AAATTTCTAA TTGTGTTGCT GATTACTCTG TGCTCTACAA CTCAACATTT TTTTCAACCT TTAAGTGTTA TGGCGTTTCT GCCACTAAGT TGAATGATCT TTGCTTCTCC AATGTCTATG CAGATTCTTT TGTAGTCAAG GGAGATGATG TAAGACAAAT AGCGCCAGGA CAAACTGGTG TTATTGCTGA TTATAATTAT AAATTGCCAG ATGATTTCAT GGGTTGTGTC CTTGCTTGGA ATACTAGGAA CATTGATGCT ACTTCAACTG GTAATTATAA TTATAAATAT AGGTATCTTA GACATGGCAA GCTTAGGCCC TTTGAGAGAG ACATATCTAA TGTGCCTTTC TCCCCTGATG GCAAACCTTG CACCCCACCT GCTCTTAATT GTTATTGGCC ATTAAATGAT TATGGTTTTT ACACCACTAC TGGCATTGGC TACCAACCTT ACAGAGTTGT AGTACTTTCT TTTGAACTTT TAAATGCACC GGCCACGGTT TGTGGACCAA AATTATCCAC TGACCTTATT AAGAACCAGT GTGTCAATTT TAATTTTAAT GGACTCACTG GTACTGGTGT GTTAACTCCT TCTTCAAAGA GATTTCAACC ATTTCAACAA TTTGGCCGTG ATGTTTCTGA TTTCACTGAT TCCGTTCGAG ATCCTAAAAC ATCTGAAATA TTAGACATTT CACCTTGCTC TTTTGGGGGT GTAAGTGTAA TTACACCTGG AACAAATGCT TCATCTGAAG TTGCTGTTCT ATATCAAGAT GTTAACTGCA CTGATGTTTC TACAGCAATT CATGCAGATC AACTCACACC AGCTTGGCGC ATATATTCTA CTGGAAACAA TGTATTCCAG ACTCAAGCAG GCTGTCTTAT AGGAGCTGAG CATGTCGACA CTTCTTATGA GTGCGACATT CCTATTGGAG CTGGCATTTG TGCTAGTTAC CATACAGTTT CTTTATTACG TAGTACTAGC CAAAAATCTA TTGTGGCTTA TACTATGTCT TTAGGTGCTG ATAGTTCAAT TGCTTACTCT AATAACACCA TTGCTATACC TACTAACTTT TCAATTAGCA TTACTACAGA AGTAATGCCT GTTTCTATGG CTAAAACCTC CGTAGATTGT AATATGTACA TCTGCGGAGA TTCTACTGAA TGTGCTAATT TGCTTCTCCA ATATGGTAGC TTTTGCACAC AACTAAATCG TGCACTCTCA GGTATTGCTG CTGAACAGGA TCGCAACACA CGTGAAGTGT TCGCTCAAGT CAAACAAATG TACAAAACCC CAACTTTGAA ATATTTTGGT GGTTTTAATT TTTCACAAAT ATTACCTGAC CCTCTAAAGC CAACTAAGAG GTCTTTTATT GAGGACTTGC TCTTTAATAA GGTGACACTC GCTGATGCTG GCTTCATGAA GCAATATGGC GAATGCCTAG GTGATATTAA TGCTAGAGAT CTCATTTGTG CGCAGAAGTT CAATGGACTT ACAGTGTTGC CACCTCTGCT CACTGATGAT ATGATTGCTG CCTACACTGC TGCTCTAGTT AGTGGTACTG CCACTGCTGG ATGGACATTT GGTGCTGGCG CTGCTCTTCA AATACCTTTT GCTATGCAAA TGGCATATAG GTTCAATGGC ATTGGAGTTA CCCAAAATGT TCTCTATGAG AACCAAAAAC AAATCGCCAA CCAATTTAAC AAGGCGATTA GTCAAATTCA AGAATCACTT ACAACAACAT CAACTGCATT GGGCAAGCTG CAAGACGTTG TTAACCAGAA TGCTCAAGCA TTAAACACAC TTGTTAAACA ACTTAGCTCT AATTTTGGTG CAATTTCAAG TGTGCTAAAT GATATCCTTT CGCGACTTGA TAAAGTCGAG GCGGAGGTAC AAATTGACAG GTTAATTACA GGCAGACTTC AAAGCCTTCA AACCTATGTA ACACAACAAC TAATCAGGGC TGCTGAAATC AGGGCTTCTG CTAATCTTGC TGCTACTAAA ATGTCTGAGT GTGTTCTTGG ACAATCAAAA AGAGTTGACT TTTGTGGAAA GGGCTACCAC CTTATGTCCT TCCCACAAGC AGCCCCGCAT GGTGTTGTCT TCCTACATGT CACGTATGTG CCATCCCAGG AGAGGAACTT CACCACAGCG CCAGCAATTT GTCATGAAGG CAAAGCATAC TTCCCTCGTG AAGGTGTTTT TGTGTTTAAT GGCACTTCTT GGTTTATTAC ACAGAGGAAC TTCTTTTCTC CACAAATAAT TACTACAGAC AATACATTTG TCTCAGGAAA TTGTGATGTC GTTATTGGCA TCATTAACAA CACAGTTTAT GATCCTCTGC AACCTGAGCT TGACTCATTC AAAGAAGAGC TGGACAAGTA CTTCAAAAAT CATACATCAC CAGATGTTGA TCTTGGCGAC ATTTCAGGCA TTAACGCTTC TGTCGTCAAC ATTCAAAAAG AAATTGACCG CCTCAATGAG GTCGCTAAAA ATTTAAATGA ATCACTCATT GACCTTCAAG AATTGGGAAA ATATGAGCAA TATATTAAAT GGCCTTGGTA TGTTTGGCTC GGCTTCATTG CTGGACTAAT TGCCATCGTC ATGGTTACAA TCTTGCTTTG TTGCATGACT AGTTGTTGCA GTTGCCTCAA GGGTGCATGC TCTTGTGGTT CTTGCTGCAA GTTTGATGAG GATGACTCTG AGCCAGTTCT CAAGGGTGTC AAATTACATT ACACA

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