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Seattle Structural Genomics Center for Infectious Disease

BobuA.00658.a: acyl carrier protein (BB_0704)

Target Characteristics

from organism: Borrelia burgdorferi B31
most recent status: in PDB
center reference id: BobuA.00658.a
is community request: True
associated disease: Lyme disease
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
I

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BobuA.00658.a.A1.GE26276 Full length( BobuA.00658.a ) 1 80 GE26276
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BobuA.00658.a.A1.PS00211 Full length( BobuA.00658.a ) 1 80
BobuA.00658.a.A1.PS00348 Full length( BobuA.00658.a ) 1 80

Structures

image of structure for 2KWL
2KWL
Deposited: 4/15/2010
Determination: NMR
Clone: BobuA.00658.a.A1.GE26276
Protein: BobuA.00658.a.A1.PS00211

Publications by SSGCID

NMR structure of an acyl-carrier protein from Borrelia burgdorferi.
Barnwal RP, Van Voorhis WC, Varani G
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. - 2011
volume 67, issue Pt 9, pages 1137-40
PMID: 21904063; PMCID: PMC3169415
PDB: 2KWL

Citations by Others

Dynamic Analysis of Backbone-Hydrogen-Bond Propensity for Protein Binding and Drug Design
CA Menndez, SR Accordino - Biopolymers for , 2016 - crcnetbase.com
PDB: 2KWL
Protein packing defects heat up interfacial water
MB Sierra, SR Accordino, JA Rodriguez-Fris? - The European Physical Journal E, 2013 - Springer
cited by: 5 others
PDB: 2KWL
Acyl carrier protein structural classification and normal mode analysis
DC Cantu, MJ Forrester, K Charov, PJ Reilly - Protein Science, 2012 - Wiley Online Library
cited by: 8 others
PDB: 2KWL

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
OrthoMCL: OG5_127028
PATRIC ID: fig|224326.49.peg.1095
RefSeq: NP_212838.1
UniProt: O51647

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MDNDEIFSKV RSIISEQLDK KEDEITTDSR FVEDLNADSL DIYELLYLLE EAFDDKIPEN EANEFETVGD VVNFIKKRKG

NT Sequence
ATGGATAATG ATGAAATTTT TAGCAAGGTT AGGTCTATTA TATCTGAGCA ACTTGATAAA AAAGAAGATG AAATTACCAC AGACTCTAGA TTTGTTGAAG ATCTTAATGC AGATAGTCTA GATATTTATG AGCTTTTGTA TTTGCTTGAA GAGGCCTTTG ATGATAAGAT TCCAGAGAAT GAAGCCAATG AATTTGAGAC GGTAGGCGAT GTTGTTAATT TTATTAAAAA GAGAAAGGGT

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