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Seattle Structural Genomics Center for Infectious Disease

BobuA.19063.a: 3-OH-3-methylglutaryl-CoA reductase (mvaA) (BB_0685)

Target Characteristics

from organism: Borrelia burgdorferi B31
most recent status: selected
center reference id: BobuA.19063.a
is community request: True
associated disease: Lyme disease
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
I

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

External Resources

Resource Reference ID
PATRIC ID: fig|224326.49.peg.1076
RefSeq: NP_212819.1
UniProt: O51628

Enzyme & Pathway Information

Pathway Pathway ID EC Number
mevalonate degradation PWY-5074 1.1.1.88

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MNLESLSSFM ELSKNFRHKS VLEKRQEIKS FLELSYKDFF YNNANEDFLF NMIENYIGYL SFPIGIVKNL KINGKYYSLP IATEESSVVA ALNFAAKILE NADLRYSLGE VLGISQIYIK SEKDLSKIFV DLGDKIKTWI EPLLTNMNQR GGGFRRLSTR HIKELGIQKL NIYVDTCDAM GANLLNSIAE RVAEFIFLEF GYECVLKVLS NDISEFTAKA RFVLDFKHLL PGKEDSWNLA KKIELISSIG FYEEERAVTN NKGIMNGITG VCLATFNDTR ALEASVHKFA SKSGKYFPLS KFYTTDNALV GEIEIPLQVG TKGGVISFNE ASILSFKIMN VNSKSEFIGI LSCVGLASNF AALRALAFNG IQKGHMRLHV NKILHLLKTK YNISDFEKDK LLLEMERMNI YSFDFAFKIL KKIRLENENK V

NT Sequence
atgaacttgg agtctttaag cagttttatg gaacttagta aaaattttag acataaaagc gttttagaaa aaaggcaaga gataaaaagt tttttggaat tatcttataa agattttttt tataataatg ccaatgaaga ttttcttttt aatatgatag aaaattatat tggatattta tcttttccta ttggaattgt aaaaaatttg aaaataaatg gcaaatacta ttctttgcca attgcaacag aagaatcttc tgttgttgct gccctaaatt ttgcggcaaa gattcttgaa aatgctgatt taaggtattc tttgggtgaa gtgttgggaa tttcgcaaat ttatataaaa tcggaaaaag atttaagtaa aatttttgtt gaccttggtg ataaaattaa gacttggatt gaacctcttt taaccaatat gaatcaaagg gggggtggat ttagaaggtt gtcaactagg cacattaaag aattaggtat tcaaaaatta aatatttatg tggatacttg tgatgctatg ggtgctaatt tgctaaactc aattgcagag cgtgtagcag aatttatttt tttagaattc ggatatgagt gtgttttaaa agttttaagc aatgatatta gtgaatttac agccaaagcc cgttttgttt tagattttaa gcatttgcta ccgggtaaag aggattcttg gaatttggct aaaaaaattg aacttatttc tagtataggt ttttacgaag aggagcgagc tgttactaat aataaaggta ttatgaatgg aattacaggg gtgtgtcttg caacttttaa tgacacaaga gctcttgagg cctctgttca taaatttgct tcaaaaagcg gcaaatattt tccccttagt aaattttata ctactgacaa tgctttagtt ggagaaattg aaattccttt gcaagttgga actaaaggtg gggttatatc ttttaatgaa gcttcaattt taagttttaa aattatgaat gtaaatagta agagcgaatt tattggtatt ctctcttgtg ttggacttgc tagtaatttt gcagcattaa gggctcttgc atttaatggg attcaaaagg gtcatatgag attgcatgtt aataaaatac tccatctttt aaagacaaaa tataatattt ctgattttga aaaagacaaa ttattattgg aaatggaaag aatgaatatt tattcttttg attttgcttt taaaattttg aagaaaataa ggttagagaa tgaaaataaa gtgtaa

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