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Seattle Structural Genomics Center for Infectious Disease

BobuA.19133.a: 3-OH-3-methylglutaryl-CoA synthase (BB_0683)

Target Characteristics

from organism: Borrelia burgdorferi B31
most recent status: soluble
center reference id: BobuA.19133.a
is community request: True
associated disease: Lyme disease
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
I

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BobuA.19133.a.B1.GE39594 full length 1 407 GE39594
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

External Resources

Resource Reference ID
PATRIC ID: fig|224326.49.peg.1074
RefSeq: NP_212817.1
UniProt: O51626

Enzyme & Pathway Information

Pathway Pathway ID EC Number
superpathway of ergosterol biosynthesis I ERGOSTEROL-SYN-PWY 2.3.3.10
superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) PWY-5910 2.3.3.10
Methanobacterium thermoautotrophicum biosynthetic metabolism PWY-6146 2.3.3.10
mevalonate pathway II (archaea) PWY-6174 2.3.3.10
ketogenesis PWY66-367 2.3.3.10
superpathway of cholesterol biosynthesis PWY66-5 2.3.3.10
isoprene biosynthesis II (engineered) PWY-7391 2.3.3.10
mevalonate pathway III (archaea) PWY-7524 2.3.3.10
ferrichrome A biosynthesis PWY-7571 2.3.3.10
mevalonate pathway I PWY-922 2.3.3.10

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MRIGISDIRI FLPLNYLDFS VLLENPLYFS NEVFFKKINR AIDATLQKGF RFTSPNEDSV TMASSAVKLI FDNNNLDLSK IRILLGGTET GVDHSKAISS YVFGALKQSG ICLGNNFLTF QVQHACAGAA MSLHTVASVL SHSNNSEYGI VFSSDIAHYS NLTTAEITQG AGATAILIEK NPKLLSINLS EFGVYTDDVD DFFRPFGSVE AKVRGQYSVE CYNNANENAL RDFAFKKQLS MKDLFSNYRF VLHVPFAKMP IDSMHYILKK YYSDDESVRN AYLESIDFYD GVEAAMEVGN LYTGSIFLSL AFYLKRVFSK KDITGEKILF CSYGSGNIMI IYELTIEKSA FDVIKLWDLE GLIKNRNNAN FEEYKDFFQN KIIPGESRGF YLKELRNDGY RVYGYRA

NT Sequence
atgagaatag gtattagtga tattagaatt tttttacctt taaattattt agatttttct gttcttttgg aaaatccttt atatttttct aatgaagttt tttttaaaaa aatcaataga gcaatagatg caaccttgca aaaaggtttt aggtttacca gtcctaatga ggatagtgta accatggcaa gttcggctgt taagcttatt tttgacaaca ataatcttga tttaagcaaa attagaatac ttttgggtgg aactgaaaca ggcgttgatc attcaaaggc catttcttct tatgtttttg gagccttaaa gcaatctggt atttgtctgg gaaataattt tctaactttc caggttcaac atgcgtgtgc tggtgctgct atgtctttgc acactgtggc aagtgtttta agccattcca ataattctga atacggcata gttttttctt cagatattgc acattatagc aatcttacta cggctgagat tacccaagga gccggcgcaa ctgcaatttt gattgaaaaa aatccaaagc tactttcgat caatttatct gaatttggag tttatactga tgatgttgac gattttttta ggccttttgg aagtgttgag gctaaggtgc gaggtcagta ttcagttgaa tgttacaata atgcaaacga aaatgcttta agagattttg ctttcaaaaa gcaacttagt atgaaagatt tattttctaa ttataggttt gttttgcatg ttccttttgc taaaatgcca atagattcaa tgcattatat tttgaaaaaa tattatagcg atgacgaatc tgttagaaat gcttatttag aatcaataga tttttacgat ggagttgaag ctgctatgga agtgggaaat ttgtatacag gttcaatttt tctatcttta gcattttatt taaaaagagt attttccaag aaagatatta caggggaaaa gatattgttt tgctcttatg gatctggcaa tattatgatt atttatgaac ttaccatcga aaagagtgct tttgatgtta ttaaattatg ggatcttgaa ggtcttataa aaaatagaaa taatgcaaat tttgaagaat ataaagattt ttttcaaaat aaaataattc ctggtgaatc cagaggattt tatttaaaag aactaaggaa tgatggatac cgagtttatg ggtatcgagc ctaa

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