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Seattle Structural Genomics Center for Infectious Disease

BrabA.00002.a: Bacterial transferase hexapeptide repeat:2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase

Target Characteristics

from organism: Brucella melitensis biovar Abortus 2308
most recent status: in PDB
center reference id: BrabA.00002.a
is community request: False
associated disease: Brucellosis
NIH risk group: 3
is select agent: True
NIH priority
pathogens category:
IIIB

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BrabA.00002.a.A1.GE25207 Full length( BrabA.00002.a ) 1 284 GE25207
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Structures

image of structure for 3EG4
3EG4
Deposited: 9/10/2008
Determination: XRay
Diffraction Image
Clone: BrabA.00002.a.A1.GE25207
Protein: BrabA.00002.a.A1.PW25245

Citations by Others

Rare Sidechain Conformations in Proteins and DNA
BJ Hintze - 2015 - search.proquest.com
PDB: 3EG4

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
OrthoMCL: OG5_134244
PATRIC ID: fig|359391.4.peg.3288
RefSeq: YP_419127
UniProt: Q2YJQ7

Enzyme & Pathway Information

Pathway Pathway ID EC Number
L-lysine biosynthesis I DAPLYSINESYN-PWY 2.3.1.117
superpathway of L-lysine, L-threonine and L-methionine biosynthesis I P4-PWY 2.3.1.117
aspartate superpathway PWY0-781 2.3.1.117

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MTKPDLASLE KTIEKAFDER DGINTATRGE VREAVEQSLI LLDRGEVRVA EKQADGNWHV NQWLKKAVLL SFRLNPMEVI KGGPGQSSWW DKVPSKFDGW TANEFEKAGF RAVPNCIVRH SAYIAPNAIL MPSFVNLGAY VDKGAMIDTW ATVGSCAQIG KNVHLSGGVG IGGVLEPMQA GPTIIEDNCF IGARSEVVEG CIVREGSVLG MGVFIGKSTK IVDRATGEVF YGEVPPYSVV VAGTMPGKNV PGENWGPSLY CAVIVKRADE KTRSKTSINE LLRD

NT Sequence
ATGACCAAGC CAGACCTCGC CTCCCTTGAG AAGACAATCG AAAAGGCTTT TGACGAGCGC GACGGTATCA ACACGGCCAC GCGCGGCGAA GTGCGCGAAG CCGTCGAACA GTCGCTCATT CTGCTCGACC GCGGTGAAGT CCGTGTCGCA GAAAAACAGG CGGACGGCAA CTGGCATGTC AACCAATGGC TGAAGAAAGC GGTTCTGCTC TCCTTCCGCC TGAACCCGAT GGAAGTCATC AAGGGCGGCC CCGGCCAGTC CTCCTGGTGG GACAAGGTTC CCTCCAAGTT CGATGGCTGG ACGGCAAACG AATTTGAAAA GGCGGGCTTC CGCGCGGTTC CCAACTGCAT CGTGCGCCAC TCGGCCTATA TCGCGCCCAA TGCCATCCTG ATGCCCTCCT TCGTCAATCT CGGCGCCTAT GTCGATAAAG GCGCCATGAT CGATACATGG GCAACCGTCG GCTCCTGCGC ACAGATTGGC AAAAACGTGC ACCTTTCCGG CGGCGTCGGC ATTGGCGGCG TTCTGGAACC CATGCAGGCG GGCCCCACCA TTATTGAAGA CAACTGCTTC ATCGGCGCGC GTTCGGAAGT GGTCGAAGGC TGCATCGTGC GCGAAGGCTC GGTGCTCGGC ATGGGCGTCT TCATTGGCAA ATCCACCAAG ATCGTGGACC GCGCAACCGG AGAGGTCTTC TATGGCGAAG TGCCTCCCTA TTCGGTCGTG GTTGCTGGCA CCATGCCGGG CAAGAACGTC CCCGGCGAAA ACTGGGGGCC GAGCCTTTAT TGCGCCGTGA TTGTCAAACG CGCGGACGAG AAGACCCGTT CCAAGACCTC GATCAACGAA TTGCTGCGCG AC

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