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Seattle Structural Genomics Center for Infectious Disease

BrabA.00007.a: Conserved hypothetical protein, ArsC related:Arsenate reductase and related

Target Characteristics

from organism: Brucella melitensis biovar Abortus 2308
most recent status: in PDB
center reference id: BrabA.00007.a
is community request: False
associated disease: Brucellosis
NIH risk group: 3
is select agent: True
NIH priority
pathogens category:
IIIB

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BrabA.00007.a.A1.PS00066 Full length( BrabA.00007.a ) 1 116
BrabA.00007.a.A1.PW25633 Full length( BrabA.00007.a ) 1 116

Structures

image of structure for 2KOK
2KOK
Deposited: 9/23/2009
Determination: NMR
Clone: BrabA.00007.a.A1.GE25588
Protein: BrabA.00007.a.A1.PB00021

Publications by SSGCID

Solution structure of an arsenate reductase-related protein, YffB, from Brucella melitensis, the etiological agent responsible for brucellosis.
Buchko GW, Hewitt SN, Myler PJ, Napuli AJ, Van Voorhis WC
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. - 2011
volume 67, issue Pt 9, pages 1129-36
PMID: 21904062; PMCID: PMC3169414
PDB: 2KOK

Citations by Others

A deep learning approach to the structural analysis of proteins
M Giulini, R Potestio- Interface focus, 2019 - royalsocietypublishing.org
cited by: 2 others
PDB: 2KOK
Structure and function prediction of arsenate reductase from Deinococcus indicus DR1
D Chauhan, PA Srivastava, V Agnihotri- Journal of molecular, 2019 - Springer
PDB: 2KOK
A new arsenate reductase involved in arsenic detoxification in Anabaena sp. PCC7120
S Pandey, AK Shrivastava, VK Singh, R Rai… - Functional & integrative …, 2013 - Springer
cited by: 6 others
PDB: 2KOK
Corynebacterium glutamicum survives arsenic stress with arsenate reductases coupled to two distinct redox mechanisms
AF Villadangos, K Van Belle, K Wahni? - Molecular Microbiology, 2011 - Wiley Online Library
cited by: 21 others
PDB: 2KOK

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
OrthoMCL: OG5_135478
PATRIC ID: fig|359391.4.peg.422
RefSeq: YP_413859
UniProt: Q2YMA4

Enzyme & Pathway Information

Pathway Pathway ID EC Number
arsenate detoxification I (glutaredoxin) PWY-4202 1.20.4.1
arsenate detoxification II (glutaredoxin) PWY-4621 1.20.4.1

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSVTIYGIKN CDTMKKARIW LEDHGIDYTF HDYKKEGLDA ETLDRFLKTV PWEQLLNRAG TTFRKLPEDV RSNVDAASAR ELMLAQPSMV KRPVLERDGK LMVGFKPAQY EAYFKL

NT Sequence
ATGAGTGTGA CCATTTACGG CATCAAGAAC TGCGACACCA TGAAGAAAGC GCGTATCTGG CTGGAAGATC ACGGCATTGA TTATACTTTT CATGATTACA AGAAGGAGGG GCTCGATGCC GAAACGCTCG ACCGTTTTCT GAAAACCGTT CCGTGGGAGC AGCTTTTGAA CCGTGCGGGC ACGACATTCC GCAAACTGCC TGAGGATGTG CGCAGCAATG TCGATGCGGC AAGCGCGCGC GAACTGATGC TGGCACAACC TTCCATGGTC AAGCGTCCGG TTCTGGAGCG GGACGGCAAG CTGATGGTGG GCTTCAAACC GGCGCAGTAT GAAGCTTATT TTAAGCTA

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