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Seattle Structural Genomics Center for Infectious Disease

BrabA.00010.b: Short-chain dehydrogenase/reductase SDR:Glucose/ribitol dehydrogenase

Target Characteristics

from organism: Brucella melitensis biovar Abortus 2308
most recent status: in PDB
center reference id: BrabA.00010.b
is community request: False
associated disease: Brucellosis
NIH risk group: 3
is select agent: True
NIH priority
pathogens category:
IIIB

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BrabA.00010.b.A1.GE25364 Full length( BrabA.00010.b ) 1 245 GE25364
BrabA.00010.b.B1.GE25460 Full length( BrabA.00010.b ) 1 245 GE25460
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Structures

image of structure for 3EMK
3EMK
Deposited: 9/24/2008
Determination: XRay
Diffraction Image
Clone: BrabA.00010.b.A1.GE25364
Protein: BrabA.00010.b.A1.PS00049
image of structure for 3ENN
3ENN
Deposited: 9/25/2008
Determination: XRay
Diffraction Image
Clone: BrabA.00010.b.A1.GE25364
Protein: BrabA.00010.b.A1.PS00049

Citations by Others

The Crystal Structure of l-Sorbose Reductase from< i> Gluconobacter frateurii Complexed with NADPH and l-Sorbose
K Kubota, K Nagata, M Okai, K Miyazono? - Journal of molecular Biology, 2011 - Elsevier
cited by: 9 others
PDB: 3EMK

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
OrthoMCL: OG5_126618
PATRIC ID: fig|359391.4.peg.504
RefSeq: YP_413943
UniProt: Q2YMG6

Enzyme & Pathway Information

Pathway Pathway ID EC Number
biotin biosynthesis I BIOTIN-BIOSYNTHESIS-PWY 1.1.1.100
(5Z)-dodecenoate biosynthesis I PWY0-862 1.1.1.100
superpathway of fatty acid biosynthesis I (E. coli) PWY0-881 1.1.1.100
arachidonate biosynthesis PWY-5353 1.1.1.100
petroselinate biosynthesis PWY-5367 1.1.1.100
cis-vaccenate biosynthesis PWY-5973 1.1.1.100
superpathway of mycolate biosynthesis PWY-6113 1.1.1.100
palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate) PWY-6282 1.1.1.100
superpathway of unsaturated fatty acids biosynthesis (E. coli) PWY-6284 1.1.1.100
superpathway of fatty acids biosynthesis (E. coli) PWY-6285 1.1.1.100
8-amino-7-oxononanoate biosynthesis I PWY-6519 1.1.1.100
eicosapentaenoate biosynthesis from arachidonate PWY-6940 1.1.1.100
docosahexanoate biosynthesis II PWY-6951 1.1.1.100
docosahexanoate biosynthesis I PWY-7053 1.1.1.100
gondoate biosynthesis (anaerobic) PWY-7663 1.1.1.100
oleate biosynthesis IV (anaerobic) PWY-7664 1.1.1.100
(5Z)-dodecenoate biosynthesis II PWY-7858 1.1.1.100
mycolate biosynthesis PWYG-321 1.1.1.100

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MFDLTGRKAL VTGATGGLGE AIARALHAQG AIVGLHGTRE EKLKELAAEL GERIFVFPAN LSDREAVKAL GQKAEEEMGG VDILVNNAGI TRDGLFVRMS DEDWDAVLTV NLTSVFNLTR ELTHPMMRRR NGRIINITSI VGVTGNPGQA NYCASKAGLI GFSKSLAQEI ASRNVTVNCI APGFIESAMT GKLNEKQKDA IMGNIPMKRM GVGADIAAAV VYLASDEAAY VTGQTLHVNG GMAMI

NT Sequence
ATGTTTGATC TGACTGGCCG CAAGGCTCTG GTGACCGGCG CAACCGGCGG TCTTGGTGAG GCGATTGCCC GCGCGCTGCA CGCGCAGGGC GCAATTGTCG GCCTGCACGG TACGCGCGAG GAAAAGCTGA AGGAATTGGC TGCGGAGCTG GGTGAACGCA TTTTCGTCTT CCCGGCCAAT CTGTCCGACC GTGAAGCCGT CAAGGCGCTT GGCCAGAAGG CCGAAGAGGA AATGGGTGGT GTCGATATTC TGGTCAACAA TGCGGGCATC ACCCGTGATG GCCTTTTCGT GCGCATGAGC GACGAGGATT GGGATGCGGT TCTGACCGTC AATCTGACGT CGGTATTCAA TCTCACGCGC GAACTGACCC ATCCCATGAT GCGCCGCCGC AACGGCCGCA TCATCAACAT CACCTCCATT GTCGGTGTGA CGGGCAATCC GGGTCAGGCA AATTATTGCG CCTCGAAGGC TGGCCTCATC GGCTTCTCCA AGTCGCTGGC GCAAGAGATC GCAAGCCGCA ACGTGACCGT CAATTGCATC GCGCCGGGCT TTATCGAATC GGCCATGACC GGCAAGCTGA ATGAGAAGCA GAAGGACGCG ATCATGGGCA ATATTCCCAT GAAGCGCATG GGGGTCGGCG CCGATATTGC TGCTGCCGTG GTCTATCTTG CAAGCGACGA GGCGGCCTAT GTGACCGGCC AGACCTTGCA TGTAAATGGC GGCATGGCCA TGATT

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