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Seattle Structural Genomics Center for Infectious Disease

BrabA.00010.g: 3-ketoacyl-(acyl-carrier-protein) reductase

Target Characteristics

from organism: Brucella melitensis biovar Abortus 2308
most recent status: in PDB
center reference id: BrabA.00010.g
is community request: True
associated disease: Brucellosis
NIH risk group: 3
is select agent: True
NIH priority
pathogens category:
IIIB

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BrabA.00010.g.A1.GE25558 Full length( BrabA.00010.g ) 1 252 GE25558
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BrabA.00010.g.A1.PS00350 Full length( BrabA.00010.g ) 1 252
BrabA.00010.g.A1.PW25603 Full length( BrabA.00010.g ) 1 252

Structures

image of structure for 3N74
3N74
Deposited: 5/26/2010
Determination: XRay
Diffraction Image
Clone: BrabA.00010.g.A1.GE25558
Protein: BrabA.00010.g.A1.PS00350
image of structure for 6B9U
6B9U
Deposited: 10/11/2017
Determination: XRay
Diffraction Image
Clone: BrabA.00010.g.A1.GE25558
Protein: BrabA.00010.g.A1.PS00350

External Resources

Resource Reference ID
OrthoMCL: OG5_168405
PATRIC ID: fig|359391.4.peg.3272
RefSeq: YP_419113.1
UniProt: Q2YJS1

Enzyme & Pathway Information

Pathway Pathway ID EC Number
biotin biosynthesis I BIOTIN-BIOSYNTHESIS-PWY 1.1.1.100
(5Z)-dodecenoate biosynthesis I PWY0-862 1.1.1.100
superpathway of fatty acid biosynthesis I (E. coli) PWY0-881 1.1.1.100
arachidonate biosynthesis PWY-5353 1.1.1.100
petroselinate biosynthesis PWY-5367 1.1.1.100
cis-vaccenate biosynthesis PWY-5973 1.1.1.100
superpathway of mycolate biosynthesis PWY-6113 1.1.1.100
palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate) PWY-6282 1.1.1.100
superpathway of unsaturated fatty acids biosynthesis (E. coli) PWY-6284 1.1.1.100
superpathway of fatty acids biosynthesis (E. coli) PWY-6285 1.1.1.100
8-amino-7-oxononanoate biosynthesis I PWY-6519 1.1.1.100
eicosapentaenoate biosynthesis from arachidonate PWY-6940 1.1.1.100
docosahexanoate biosynthesis II PWY-6951 1.1.1.100
docosahexanoate biosynthesis I PWY-7053 1.1.1.100
gondoate biosynthesis (anaerobic) PWY-7663 1.1.1.100
oleate biosynthesis IV (anaerobic) PWY-7664 1.1.1.100
(5Z)-dodecenoate biosynthesis II PWY-7858 1.1.1.100
mycolate biosynthesis PWYG-321 1.1.1.100

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSLEGKVALI TGAGSGFGEG MAKRFAKGGA KVVIVDRDKA GAERVAGEIG DAALAVAADI SKEADVDAAV EAALSKFGKV DILVNNAGIG HKPQNAELVE PEEFDRIVGV NVRGVYLMTR KLIPHFKENG AKGQECVILN VASTGAGRPR PNLAWYNATK GWVVSVTKAL AIELAPAKIR VVALNPVAGE TPLLTTFMGE DSEEIRKKFR DSIPMGRLLK PDDLAEAAAF LCSPQASMIT GVALDVDGGR SI

NT Sequence
GTGTCGCTTG AAGGTAAGGT CGCGCTCATT ACGGGAGCAG GTTCGGGGTT TGGTGAAGGC ATGGCGAAAC GCTTTGCCAA GGGCGGCGCG AAGGTCGTCA TCGTGGATCG CGACAAGGCG GGTGCCGAAC GTGTGGCCGG TGAAATCGGC GATGCGGCGC TGGCTGTTGC TGCCGATATT TCCAAAGAAG CCGATGTCGA TGCGGCGGTG GAGGCTGCAT TATCGAAATT CGGCAAGGTC GATATTCTCG TCAACAATGC CGGTATCGGC CACAAGCCGC AAAATGCCGA GCTGGTGGAG CCGGAAGAGT TCGACCGTAT TGTGGGTGTC AATGTGCGCG GCGTCTATCT GATGACCCGC AAGCTTATTC CGCATTTCAA GGAGAATGGT GCCAAGGGAC AAGAATGCGT AATCCTCAAC GTCGCTTCGA CCGGGGCCGG GCGCCCGCGC CCGAATCTCG CCTGGTACAA TGCAACCAAG GGCTGGGTTG TTTCGGTGAC GAAGGCGCTG GCCATCGAGC TTGCACCGGC AAAGATTCGC GTGGTGGCGC TGAACCCGGT GGCGGGTGAA ACGCCGCTTC TCACCACCTT CATGGGTGAG GATAGCGAGG AAATCCGCAA GAAATTCCGC GATTCCATTC CGATGGGCCG CCTGTTGAAA CCTGACGATC TGGCTGAAGC TGCGGCTTTC CTTTGCTCGC CTCAAGCCTC TATGATTACA GGCGTTGCGC TCGACGTGGA TGGCGGGCGT TCGATC

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