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Seattle Structural Genomics Center for Infectious Disease

BrabA.00052.a: Glyceraldehyde 3-phosphate dehydrogenase:TrkA potassium uptake protein:Glyceraldehyde-3-phosphate dehydrogenase, type I

Target Characteristics

from organism: Brucella melitensis biovar Abortus 2308
most recent status: in PDB
center reference id: BrabA.00052.a
is community request: False
associated disease: Brucellosis
NIH risk group: 3
is select agent: True
NIH priority
pathogens category:
IIIB

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BrabA.00052.a.A1.GE25222 Full length( BrabA.00052.a ) 1 335 GE25222
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BrabA.00052.a.D11.PD00018 Full length( BrabA.00052.a ) 1 335

Structures

image of structure for 3DOC
3DOC
Deposited: 7/3/2008
Determination: XRay
Diffraction Image
Clone:
Protein: BrabA.00052.a.D11.PD00018

Citations by Others

'Cold spots' in protein cold adaptation: Insights from normalized atomic displacement parameters (< i> B'-factors)
A Siglioccolo, R Gerace, S Pascarella - Biophysical chemistry, 2010 - Elsevier
cited by: 13 others
PDB: 3DOC

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
OrthoMCL: OG5_126628
PATRIC ID: fig|359391.4.peg.1802
RefSeq: YP_415091
UniProt: Q2YRE0

Enzyme & Pathway Information

Pathway Pathway ID EC Number
homolactic fermentation ANAEROFRUCAT-PWY 1.2.1.12
glycolysis III (from glucose) ANAGLYCOLYSIS-PWY 1.2.1.12
gluconeogenesis I GLUCONEO-PWY 1.2.1.12
glycolysis I (from glucose 6-phosphate) GLYCOLYSIS 1.2.1.12
superpathway of glycolysis and the Entner-Doudoroff pathway GLYCOLYSIS-E-D 1.2.1.12
superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass GLYCOLYSIS-TCA-GLYOX-BYPASS 1.2.1.12
superpathway of hexitol degradation (bacteria) HEXITOLDEGSUPER-PWY 1.2.1.12
heterolactic fermentation P122-PWY 1.2.1.12
Bifidobacterium shunt P124-PWY 1.2.1.12
formaldehyde assimilation III (dihydroxyacetone cycle) P185-PWY 1.2.1.12
superpathway of N-acetylneuraminate degradation P441-PWY 1.2.1.12
hexitol fermentation to lactate, formate, ethanol and acetate P461-PWY 1.2.1.12
glycolysis IV (plant cytosol) PWY-1042 1.2.1.12
superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle PWY-5464 1.2.1.12
glycolysis II (from fructose 6-phosphate) PWY-5484 1.2.1.12
gluconeogenesis III PWY66-399 1.2.1.12
glycolysis VI (metazoan) PWY66-400 1.2.1.12
superpathway of glucose and xylose degradation PWY-6901 1.2.1.12
glycerol degradation to butanol PWY-7003 1.2.1.12
superpathway of anaerobic sucrose degradation PWY-7345 1.2.1.12
sucrose biosynthesis I (from photosynthesis) SUCSYN-PWY 1.2.1.12

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MAVRVAINGF GRIGRNILRA IVESGRTDIQ VVAINDLGPV ETNAHLLRYD SVHGRFPKEV EVAGDTIDVG YGPIKVHAVR NPAELPWKEE NVDIALECTG IFTSRDKAAL HLEAGAKRVI VSAPADGADL TVVYGVNNDK LTKDHLVISN ASCTTNCLAP VAQVLNDTIG IEKGFMTTIH SYTGDQPTLD TMHKDLYRAR AAALSMIPTS TGAAKAVGLV LPELKGKLDG VAIRVPTPNV SVVDLTFIAK RETTVEEVNN AIREAANGRL KGILGYTDEK LVSHDFNHDS HSSVFHTDQT KVMDGTMVRI LSWYDNEWGF SSRMSDTAVA LGKLI

NT Sequence
ATGGCAGTTC GCGTCGCAAT CAACGGTTTT GGCCGCATTG GCCGTAACAT CCTTCGCGCC ATCGTGGAAT CGGGGCGCAC CGACATTCAG GTCGTCGCCA TCAACGATCT CGGCCCGGTC GAAACCAACG CACATCTTCT GCGTTATGAC AGCGTTCATG GCCGTTTCCC CAAGGAAGTG GAGGTTGCAG GCGATACGAT CGATGTTGGC TACGGCCCGA TCAAGGTTCA TGCCGTCCGC AACCCGGCCG AACTGCCGTG GAAGGAAGAA AACGTCGATA TCGCCCTTGA ATGCACCGGC ATTTTCACCT CGCGCGACAA GGCAGCACTT CATCTTGAAG CTGGCGCCAA GCGCGTCATC GTCTCCGCTC CCGCAGACGG TGCCGATCTC ACCGTCGTCT ATGGTGTCAA CAACGACAAG CTGACGAAGG ACCATCTGGT CATCTCCAAC GCTTCGTGTA CCACCAACTG CCTTGCGCCG GTGGCTCAGG TTCTCAACGA TACTATCGGT ATCGAAAAGG GCTTCATGAC CACGATCCAC TCCTATACGG GCGACCAGCC GACGCTGGAC ACCATGCACA AGGATCTCTA CCGCGCCCGC GCCGCTGCCC TTTCCATGAT CCCGACCTCG ACGGGTGCGG CCAAGGCCGT CGGTCTCGTT CTGCCGGAAC TGAAAGGCAA GCTCGACGGC GTTGCCATTC GCGTCCCGAC CCCAAATGTC TCGGTCGTTG ATCTCACCTT CATCGCCAAG CGTGAAACCA CCGTTGAAGA AGTCAACAAT GCGATCCGCG AAGCCGCCAA TGGCCGCCTC AAGGGCATTC TCGGCTATAC CGATGAGAAG CTCGTCTCGC ACGACTTCAA CCACGATTCC CATTCCTCGG TCTTCCACAC CGACCAGACC AAGGTTATGG ACGGCACCAT GGTGCGTATC CTGTCGTGGT ACGACAATGA ATGGGGCTTC TCCAGCCGCA TGAGCGACAC CGCCGTCGCT TTGGGCAAGC TGATC

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