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Seattle Structural Genomics Center for Infectious Disease

BrabA.17241.a: 1-deoxy-D-xylulose-5-phosphate synthase (DOXP/dxs/dxp)

Target Characteristics

from organism: Brucella melitensis biovar Abortus 2308
most recent status: selected
center reference id: BrabA.17241.a
is community request: True
associated disease: Brucellosis
NIH risk group: 3
is select agent: True
NIH priority
pathogens category:
IIIB

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

External Resources

Resource Reference ID
OrthoMCL: OG5_129068
PATRIC ID: fig|359391.4.peg.483
RefSeq: YP_413922.1
UniProt: Q2YMF0

Enzyme & Pathway Information

Pathway Pathway ID EC Number
methylerythritol phosphate pathway I NONMEVIPP-PWY 2.2.1.7
superpathway of pyridoxal 5'-phosphate biosynthesis and salvage PWY0-845 2.2.1.7
superpathway of geranylgeranyl diphosphate biosynthesis II (via MEP) PWY-5121 2.2.1.7
isoprene biosynthesis I PWY-6270 2.2.1.7
thiazole biosynthesis II (aerobic bacteria) PWY-6891 2.2.1.7
thiazole biosynthesis I (facultative anaerobic bacteria) PWY-6892 2.2.1.7
superpathway of thiamine diphosphate biosynthesis II PWY-6895 2.2.1.7
superpathway of ergosterol biosynthesis II PWY-7156 2.2.1.7
taxadiene biosynthesis (engineered) PWY-7392 2.2.1.7
methylerythritol phosphate pathway II PWY-7560 2.2.1.7
pyridoxal 5'-phosphate biosynthesis I PYRIDOXSYN-PWY 2.2.1.7
superpathway of thiamine diphosphate biosynthesis I THISYN-PWY 2.2.1.7

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSRPSTPLLD KAPTPDRLRA LPEQDLPQLA EELRTELIDA VSTTGGHLGA GLGVVELTVA LHHVFNTPYD RIIWDVGHQA YPHKILTGRR DRIRTLRQAG GLSGFTKRAE SEYDPFGAAH SSTSISAGLG MAVASELSGE KRNVIAVIGD GSMSAGMAYE AMNNAGALDA RLIVILNDND MSIAPPTGAM SAYLARLVSG RTYRSVREAA KQVAQKLPKF LQDKARKSEE YARAFFTGGT LFEELGFYYV GPIDGHNLDH LLPVLKNVRD TQKGPVLIHV VTQKGKGYAP AEAAADKYHG VNKFDVITGK QAKPPANAPS YTKIFGTSLI EEARHDDKIV AVTAAMPTGT GLDLFGEAFP KRVFDVGIAE QHAVTFAAGL ASEGYKPFCA IYSTFLQRGY DQVVHDVSIQ NLPVRFPIDR AGLVGADGPT HAGSFDTGFL AALPGFVVMA ASDEAELRHM VRTAAEYDEG PISFRYPRGD GVGVDLPERG SVLEIGKGRI VREGTKVALL SFGTRLQECL AAAEELGAAG LSTTVADARF AKPLDHDLIR RLVREHEVLV MVEEGAVGGF SSHVLQFLAT DGLLDRGLKV RALMLPDIYQ DHGKPDAMYA EAGLDRTGIV RTVFAALHRD ELGHEALPTP FRA

NT Sequence
ATGTCCCGAC CCTCAACACC GCTCCTCGAT AAGGCGCCGA CGCCAGACCG TCTTCGCGCC CTGCCGGAGC AGGACCTGCC GCAACTGGCG GAAGAATTGC GCACCGAGCT GATCGACGCG GTTTCCACCA CGGGCGGGCA TCTGGGCGCG GGCTTGGGCG TTGTGGAATT GACGGTTGCG TTGCATCATG TTTTCAACAC ACCCTATGAT CGCATCATCT GGGATGTCGG CCATCAGGCC TATCCGCACA AGATCCTGAC CGGGCGGCGC GACCGCATCC GCACATTGCG CCAGGCGGGC GGGCTTTCGG GCTTCACCAA GCGTGCGGAG AGCGAATACG ATCCCTTTGG CGCGGCCCAT TCCTCGACCT CCATTTCCGC AGGCCTCGGC ATGGCGGTGG CGAGCGAGCT TTCGGGCGAA AAGCGCAATG TGATCGCCGT CATCGGCGAT GGTTCCATGT CAGCGGGCAT GGCCTATGAA GCGATGAACA ATGCCGGTGC GCTGGATGCG CGCCTGATCG TTATTCTCAA CGACAATGAT ATGTCGATTG CGCCGCCGAC GGGCGCGATG AGTGCCTATC TGGCGCGCCT CGTTTCCGGG CGCACCTATC GCAGTGTGCG CGAGGCGGCG AAGCAGGTGG CGCAAAAGCT GCCCAAATTC CTTCAGGACA AGGCGCGCAA ATCGGAAGAA TATGCCCGCG CCTTTTTCAC CGGCGGTACG CTGTTCGAGG AGCTTGGCTT CTATTATGTC GGCCCGATCG ACGGGCATAA TCTCGACCAC CTGCTGCCGG TTCTGAAAAA TGTCCGCGAT ACGCAGAAAG GCCCGGTGCT GATCCATGTC GTGACACAGA AGGGTAAGGG CTATGCGCCG GCCGAAGCTG CCGCCGACAA ATATCACGGC GTCAACAAGT TCGACGTCAT CACCGGCAAG CAGGCGAAGC CCCCGGCAAA TGCGCCGAGC TACACCAAGA TTTTCGGCAC AAGCCTGATT GAGGAAGCGC GCCACGACGA CAAGATCGTC GCCGTCACCG CCGCCATGCC GACAGGCACG GGGCTGGACC TTTTTGGCGA GGCTTTCCCG AAGCGCGTCT TCGATGTCGG CATTGCCGAG CAGCATGCCG TCACATTCGC TGCCGGTCTT GCAAGCGAGG GGTACAAGCC CTTCTGCGCC ATTTATTCCA CCTTTCTCCA GCGCGGCTAC GATCAGGTCG TGCACGATGT TTCGATCCAG AACCTGCCCG TGCGCTTCCC CATCGACCGC GCCGGGCTGG TGGGCGCGGA TGGCCCCACC CATGCAGGCT CGTTCGATAC GGGCTTTCTT GCAGCCCTTC CGGGCTTCGT GGTGATGGCC GCATCTGACG AAGCCGAGCT TCGCCATATG GTGCGCACGG CTGCCGAATA TGACGAAGGC CCGATCTCCT TCCGCTATCC GCGCGGTGAT GGTGTGGGCG TCGATCTGCC GGAGCGCGGC TCGGTGCTGG AAATCGGCAA GGGCCGCATC GTGCGCGAAG GCACCAAGGT GGCGCTTCTT TCCTTCGGTA CACGCTTGCA GGAATGTCTT GCAGCCGCTG AAGAACTGGG CGCTGCCGGC CTGTCGACGA CAGTGGCCGA TGCACGTTTC GCCAAGCCGC TCGACCATGA CCTGATCCGC CGTCTGGTGC GTGAACATGA AGTGCTGGTG ATGGTGGAAG AAGGTGCGGT CGGCGGGTTT AGCAGCCATG TGCTGCAATT CCTCGCCACG GACGGGCTTC TGGATCGCGG CCTCAAGGTG CGGGCGCTGA TGCTCCCCGA TATCTATCAG GACCATGGCA AGCCGGATGC CATGTATGCC GAAGCGGGCC TTGACCGTAC GGGCATTGTG CGCACGGTTT TTGCCGCACT TCATCGCGAT GAACTGGGCC ATGAAGCACT GCCGACACCG TTTCGTGCC

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