NIAID Emerging and Re-emerging Infectious Diseases NIAID Bioinformatics Resource Centers NIAID Structural Genomic Centers Center for Structural Genomics of Infectious Disease
Seattle Structural Genomics Center for Infectious Disease

BrmeB.01563.a: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22)

Target Characteristics

from organism: Brucella melitensis ATCC 23457
most recent status: in PDB
center reference id: BrmeB.01563.a
is community request: True
associated disease: Brucellosis
NIH risk group: 3
is select agent: True
NIH priority
pathogens category:
IIIB

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BrmeB.01563.a.B1.GE36941 Full length( BrmeB.01563.a ) 1 320 GE36941
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BrmeB.01563.a.B1.PS01874 Full length( BrmeB.01563.a ) 1 320
BrmeB.01563.a.B1.PS01875 Full length( BrmeB.01563.a ) 1 320

Structures

image of structure for 4MPQ
4MPQ
Deposited: 9/13/2013
Determination: XRay
Diffraction Image
Clone: BrmeB.01563.a.B1.GE36941
Protein: BrmeB.01563.a.B1.PS01874
image of structure for 4O0K
4O0K
Deposited: 12/13/2013
Determination: XRay
Diffraction Image
Clone: BrmeB.01563.a.B1.GE36941
Protein: BrmeB.01563.a.B1.PS01875

Citations by Others


This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
PATRIC ID: fig|546272.3.peg.2505
RefSeq: YP_002734061.1
UniProt: C0RKH4

Enzyme & Pathway Information

Pathway Pathway ID EC Number
trans-4-hydroxy-L-proline degradation II PWY-5159 3.5.4.22
L-lysine biosynthesis I DAPLYSINESYN-PWY 4.3.3.7
superpathway of L-lysine, L-threonine and L-methionine biosynthesis I P4-PWY 4.3.3.7
aspartate superpathway PWY0-781 4.3.3.7
L-lysine biosynthesis II PWY-2941 4.3.3.7
L-lysine biosynthesis III PWY-2942 4.3.3.7
L-lysine biosynthesis VI PWY-5097 4.3.3.7
superpathway of L-lysine, L-threonine and L-methionine biosynthesis II PWY-724 4.3.3.7

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MKAEIFSGVI PALMTPCKPD RSPDFDALVR KGQELIGDGM SAVVYCGSMG DWPLLTDAQR MEGVERLVKA GIPVIVGTGA VNTASAVAHA AHAQKVGAKG LMVIPRVLSR GSAIAAQKAY FKAILSAAPD LPAVIYNSPY YGFATRADLF FDLRAEHPNL VGFKEFGGPA DMRYAAENIT SRDDGVSLMI GVDTAVFHGF VNCGATGAIT GIGNVLPKEV IHLCNLSQAA ALGDVDARQR AQELEQALAV LSSFDEGPDL VLYFKHMMVL KGDKEYTLHF NETDALSESQ RGYVETQFRL FNTWYAEWSK LPGAVQRCKA

NT Sequence
TTGAAAGCCG AGATTTTTTC CGGGGTGATC CCCGCTCTGA TGACACCGTG CAAGCCGGAC CGCAGCCCTG ATTTCGATGC GCTCGTGCGC AAGGGGCAGG AGCTGATTGG CGATGGTATG TCGGCGGTCG TCTATTGTGG TTCGATGGGC GATTGGCCGC TTCTGACGGA TGCGCAGCGC ATGGAGGGCG TGGAGCGTCT GGTAAAGGCC GGTATTCCCG TTATCGTCGG CACCGGCGCA GTCAATACGG CATCGGCTGT CGCTCATGCC GCACACGCGC AGAAAGTGGG CGCAAAGGGC CTTATGGTGA TCCCGCGCGT TCTGTCTCGC GGCTCGGCCA TTGCGGCGCA GAAGGCATAT TTCAAGGCAA TCCTTTCGGC GGCGCCGGAC CTGCCTGCGG TGATCTATAA CAGCCCCTAT TACGGCTTTG CCACGCGTGC CGATCTGTTT TTTGACCTGC GCGCCGAACA TCCAAATCTC GTTGGCTTCA AGGAATTCGG CGGCCCGGCG GACATGCGTT ATGCGGCGGA AAACATCACC AGCCGTGATG ATGGTGTTTC GCTGATGATC GGCGTCGATA CGGCCGTGTT CCATGGTTTT GTGAATTGCG GCGCAACGGG TGCGATTACC GGCATCGGCA ATGTGCTGCC AAAAGAAGTC ATTCACCTTT GCAATCTCTC GCAGGCAGCC GCCTTGGGCG ATGTCGATGC GCGCCAGCGC GCACAGGAAC TGGAACAGGC GCTTGCCGTC CTGTCCTCTT TCGATGAGGG ACCGGATCTG GTCCTCTACT TCAAGCACAT GATGGTGCTG AAGGGGGACA AGGAATATAC GCTGCATTTC AACGAGACCG ACGCATTGAG CGAAAGCCAG CGCGGCTATG TCGAAACGCA GTTCAGGCTT TTCAACACCT GGTATGCCGA GTGGAGCAAA CTGCCGGGTG CCGTACAGCG CTGCAAGGCG

© 2019 Center for Infectious Disease Research. All rights reserved. Contact ssgcid@cidresearch.org with questions or feedback.