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Seattle Structural Genomics Center for Infectious Disease

BuceA.00020.k: 2-aminomuconate 6-semialdehyde dehydrogenase

Target Characteristics

from organism: Burkholderia cenocepacia J2315
most recent status: in PDB
center reference id: BuceA.00020.k
is community request: False
associated disease:
NIH risk group: 3
is select agent: False
NIH priority
pathogens category:
IIIB

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BuceA.00020.k.B1.GE36442 Full length( BuceA.00020.k ) 1 496 GE36442
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Structures

image of structure for 4U3W
4U3W
Deposited: 7/23/2014
Determination: XRay
Diffraction Image
Clone: BuceA.00020.k.B1.GE36442
Protein: BuceA.00020.k.B1.PW37245

External Resources

Resource Reference ID
OrthoMCL: OG5_132910
PATRIC ID: fig|216591.5.peg.5903
RefSeq: YP_002234732.1
UniProt: B4EFS9

Enzyme & Pathway Information

Pathway Pathway ID EC Number
4-nitrotoluene degradation II PWY-5644 1.2.1.32
4-chloronitrobenzene degradation PWY-5645 1.2.1.32
2-nitrobenzoate degradation I PWY-5647 1.2.1.32
2-amino-3-carboxymuconate semialdehyde degradation to glutaryl-CoA PWY-5652 1.2.1.32
2-amino-3-carboxymuconate semialdehyde degradation to 2-hydroxypentadienoate PWY-5654 1.2.1.32
L-tryptophan degradation IX PWY-5655 1.2.1.32
2-aminophenol degradation PWY-6210 1.2.1.32
L-tryptophan degradation XI (mammalian, via kynurenine) PWY-6309 1.2.1.32
L-tryptophan degradation XII (Geobacillus) PWY-6505 1.2.1.32
L-tryptophan degradation III (eukaryotic) TRYPTOPHAN-DEGRADATION-1 1.2.1.32
toluene degradation IV (aerobic) (via catechol) PWY-5178 1.2.1.85
superpathway of aerobic toluene degradation PWY-5183 1.2.1.85
catechol degradation to 2-hydroxypentadienoate II PWY-5419 1.2.1.85
catechol degradation II (meta-cleavage pathway) PWY-5420 1.2.1.85
meta cleavage pathway of aromatic compounds PWY-5430 1.2.1.85
protocatechuate degradation III (para-cleavage pathway) PWY-6336 1.2.1.85
superpathway of aromatic compound degradation via 2-hydroxypentadienoate PWY-6954 1.2.1.85
4-amino-3-hydroxybenzoate degradation PWY-7006 1.2.1.85
2,3-dihydroxybenzoate degradation PWY-7480 1.2.1.85

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MTTQLNSTSR DRQLLRHYIN GEFVASGTTF PNLSPVDGRK LADVCEADAA LVDSAVQAAH AAQKAGWRDT TPAQRAAWLH KIADGIEARF DEFVAAEVAD TGRPVAQART LDIARGIANF RTFADLVRTA SGEYFETHAA DGSELINYVT RKPLGVIGII SPWNLPLLLF TWKVAPALAM GNCVVAKPSE ETPSSATLLA EVMHDVGLPP GVFNLIHGHG QNAAGEFLTR HPDISAITFT GESRTGSTIM KAVADGVKEV SFELGGKNAA VVFADADFDA AVAGVLRSSF TNAGQVCLCS ERVYVERPIF ERFVAALKEQ AQALRVGAPE DPATTMGPLI SRGHRDKVLS YFRLAVEEGA TVVTGGGAPS FGDARDDGAF VMPTIWTGLP DSARCVREEI FGPVCHIAPF DDEAEVVKRV NDSAYGLAAS IWTTQLARGH RVAKQIETGI VWVNAWFVRD LRTPFGGTKL SGLGREGGRH SLDFYSELTN VCVRIA

NT Sequence
GTGACAACTC AATTGAATTC GACCTCGCGC GACCGGCAGT TGTTGCGCCA TTACATCAAC GGTGAGTTTG TGGCGAGCGG CACAACCTTT CCAAACCTCA GTCCGGTCGA CGGTCGCAAG CTTGCCGACG TTTGCGAAGC AGATGCGGCG CTCGTGGATA GCGCCGTACA GGCGGCTCAC GCGGCGCAGA AGGCCGGCTG GCGCGACACG ACGCCCGCGC AACGGGCGGC ATGGCTGCAT AAGATCGCGG ACGGCATCGA GGCCCGCTTC GACGAATTCG TGGCGGCGGA AGTCGCCGAT ACCGGTCGGC CTGTCGCGCA GGCCCGCACC CTCGACATCG CACGTGGCAT TGCCAATTTC CGGACCTTTG CCGACCTTGT CCGCACCGCG AGCGGTGAGT ACTTCGAAAC GCATGCGGCG GACGGCAGCG AGCTGATCAA CTACGTGACG CGCAAGCCGC TCGGCGTGAT CGGCATCATA TCGCCGTGGA ACCTGCCTCT GCTGTTGTTC ACGTGGAAGG TGGCGCCGGC GCTGGCAATG GGCAACTGTG TGGTCGCCAA GCCCTCCGAG GAGACACCCA GCTCCGCAAC GTTGCTCGCC GAAGTCATGC ACGACGTCGG CTTGCCACCC GGCGTCTTCA ATCTGATTCA TGGGCACGGC CAGAACGCGG CCGGCGAATT CCTGACGCGT CATCCGGATA TCAGTGCAAT CACGTTCACG GGCGAGTCGC GCACCGGCAG CACGATCATG AAGGCCGTTG CGGACGGCGT GAAAGAGGTT TCGTTCGAGC TGGGCGGCAA GAACGCGGCC GTCGTGTTCG CGGACGCGGA CTTCGATGCC GCGGTTGCCG GCGTCCTTCG GTCCAGTTTC ACGAACGCCG GCCAGGTCTG CCTGTGCAGT GAGCGGGTGT ATGTGGAGCG GCCGATCTTC GAGCGCTTCG TCGCGGCGCT CAAGGAACAG GCGCAAGCAT TGCGCGTTGG CGCGCCGGAA GATCCCGCCA CGACGATGGG ACCGCTCATT TCGCGCGGCC ATCGCGACAA GGTGCTGTCG TATTTTCGTC TTGCCGTCGA AGAAGGCGCG ACGGTCGTGA CCGGTGGTGG CGCCCCGAGC TTCGGCGATG CACGGGACGA CGGCGCGTTT GTGATGCCGA CGATCTGGAC GGGCTTGCCG GATTCCGCCC GATGCGTACG GGAAGAGATT TTCGGACCGG TGTGCCACAT CGCGCCGTTC GACGACGAAG CGGAGGTCGT GAAGCGCGTC AACGACAGTG CTTATGGTCT TGCCGCAAGC ATCTGGACGA CGCAGCTTGC GCGCGGCCAT CGCGTCGCGA AGCAGATCGA GACGGGCATC GTGTGGGTCA ATGCGTGGTT CGTGCGCGAT CTGCGCACAC CCTTCGGTGG CACCAAACTG TCAGGACTGG GACGCGAGGG GGGCCGCCAT TCGCTCGACT TCTATTCCGA ATTGACGAAC GTTTGCGTGA GGATTGCA

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