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Seattle Structural Genomics Center for Infectious Disease

BupsA.00002.a: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase

Target Characteristics

from organism: Burkholderia pseudomallei 1710b
most recent status: in PDB
center reference id: BupsA.00002.a
is community request: False
associated disease: Melioidosis
NIH risk group: 3
is select agent: True
NIH priority
pathogens category:
IIIB

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BupsA.00002.a.A1.GE24980 Full length( BupsA.00002.a ) 1 312 GE24980
BupsA.00002.a.A2.GE27900 Created from Decode construct for feature BupsA.00002.a 37 312 GE27900
BupsA.00002.a.A3.GE27901 Created from Decode construct for feature BupsA.00002.a 41 312 GE27901
BupsA.00002.a.A4.GE27902 Created from Decode construct for feature BupsA.00002.a 53 312 GE27902
BupsA.00002.a.A5.GE27903 Created from Decode construct for feature BupsA.00002.a 55 312 GE27903
BupsA.00002.a.A6.GE27904 Created from Decode construct for feature BupsA.00002.a 65 312 GE27904
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BupsA.00002.a.A2.PS00457 Created from Decode construct for feature BupsA.00002.a 37 312
BupsA.00002.a.A3.PS00470 Created from Decode construct for feature BupsA.00002.a 41 312
BupsA.00002.a.A1.PW25018 Full length( BupsA.00002.a ) 1 312

Structures

image of structure for 3TK8
3TK8
Deposited: 8/25/2011
Determination: XRay
Diffraction Image
Clone: BupsA.00002.a.A2.GE27900
Protein: BupsA.00002.a.A2.PS00457

Citations by Others

Homo Multimer Protein Complexes
P Kangueane, C Nilofer- Protein-Protein and Domain-Domain Interactions, 2018 - Springer
PDB: 3TK8

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
OrthoMCL: OG5_134244
PATRIC ID: fig|320372.6.peg.2721
RefSeq: YP_333986
UniProt: Q3JR17

Enzyme & Pathway Information

Pathway Pathway ID EC Number
L-lysine biosynthesis I DAPLYSINESYN-PWY 2.3.1.117
superpathway of L-lysine, L-threonine and L-methionine biosynthesis I P4-PWY 2.3.1.117
aspartate superpathway PWY0-781 2.3.1.117

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MRRRRAAHRR FLPRPRPLNA RRNAPIHSSS TSSIATNMSQ QLQQIIDNAW ENRAELSPKA ASAEIREAVA HAIEQLDRGA LRVAEKIDGA WTVHQWLKKA VLLSFRLEDN APMPAGGYSQ FYDKVPSKFA NYTAEDFAAG GFRVVPPAIA RRGSFIAKNV VLMPSYTNIG AYVDEGTMVD TWATVGSCAQ IGKNVHLSGG VGIGGVLEPL QANPVIIEDN CFIGARSEVV EGVIVEENSV ISMGVYLGQS TKIYDRETGE VTYGRIPAGS VVVAGNLPAK DGTHSLYCAV IVKKVDAKTR AKVGLNELLR GD

NT Sequence
ATGCGTCGAA GGCGCGCAGC GCATCGTCGA TTTCTGCCGC GGCCTCGCCC GCTGAACGCG CGCCGAAACG CCCCGATTCA TTCATCATCC ACGTCCAGCA TAGCCACGAA CATGTCGCAA CAACTTCAGC AAATCATCGA TAACGCCTGG GAAAACCGCG CCGAGCTGTC GCCGAAGGCC GCCTCCGCGG AAATTCGCGA AGCCGTCGCG CATGCGATCG AGCAGCTCGA CCGCGGCGCG CTGCGCGTCG CCGAGAAGAT CGACGGCGCA TGGACCGTGC ACCAGTGGCT GAAGAAGGCC GTGCTGCTGT CGTTTCGCCT CGAGGACAAC GCGCCGATGC CGGCGGGCGG CTACTCGCAG TTCTACGACA AGGTGCCGTC GAAGTTCGCG AACTACACCG CCGAAGACTT CGCGGCGGGC GGCTTTCGCG TCGTGCCGCC CGCGATCGCG CGCCGCGGCT CGTTCATCGC GAAGAACGTC GTGCTGATGC CGTCGTACAC GAACATCGGC GCGTACGTCG ACGAAGGCAC GATGGTCGAC ACCTGGGCCA CCGTCGGCTC GTGCGCGCAG ATCGGCAAGA ACGTGCATCT GTCGGGCGGC GTCGGCATCG GCGGCGTGCT CGAGCCGCTG CAGGCGAACC CCGTCATCAT CGAGGACAAC TGCTTCATCG GCGCGCGCTC GGAGGTGGTC GAGGGCGTGA TCGTCGAGGA AAACTCGGTG ATCTCGATGG GCGTGTATCT CGGCCAGAGC ACGAAGATCT ACGACCGCGA GACAGGCGAA GTGACGTACG GCCGCATTCC GGCCGGCTCG GTCGTCGTCG CGGGCAACCT GCCGGCGAAG GACGGCACGC ACAGCCTGTA CTGCGCGGTG ATCGTGAAGA AGGTCGACGC GAAGACCCGC GCGAAGGTCG GCCTGAACGA ACTGCTGCGA GGCGAC

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