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Seattle Structural Genomics Center for Infectious Disease

BupsA.00025.a: NAD(+) synthetase

Target Characteristics

from organism: Burkholderia pseudomallei 1710b
most recent status: in PDB
center reference id: BupsA.00025.a
is community request: False
associated disease: Melioidosis
NIH risk group: 3
is select agent: True
NIH priority
pathogens category:
IIIB

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BupsA.00025.a.A1.GE25000 Full length( BupsA.00025.a ) 1 284 GE25000
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BupsA.00025.a.A1.PW25038 Full length( BupsA.00025.a ) 1 284

Structures

image of structure for 3DPI
3DPI
Deposited: 7/8/2008
Determination: XRay
Diffraction Image
Clone: BupsA.00025.a.A1.GE25000
Protein: BupsA.00025.a.A1.PW25038

Citations by Others

Protein-protein interaction and molecular dynamics analysis for identification of novel inhibitors in Burkholderia cepacia GG4
M Gupta, R Chauhan, Y Prasad, G Wadhwa - Biology and Chemistry, 2016 - Elsevier
PDB: 3DPI

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
OrthoMCL: OG5_127076
PATRIC ID: fig|320372.6.peg.4530
RefSeq: YP_335674
UniProt: Q3JL79

Enzyme & Pathway Information

Pathway Pathway ID EC Number
aspartate superpathway PWY0-781 6.3.1.5
NAD de novo biosynthesis I (from aspartate) PYRIDNUCSYN-PWY 6.3.1.5

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSRPDQAARR RAIAAELHVS PTFDARDEAE RRIGFVADYL RTAGLRACVL GISGGIDSST AGRLAQLAVE RLRASGYDAR FVAMRLPYGA QHDEADARRA LAFVRADETL TVDVKPAADA MLAALAAGGL AYLDHAQQDF VLGNIKARER MIAQYAVAGA RNGVVIGTDH AAESVMGFFT KFGDGGADVL PLAGLTKRRV RALARMLGAD EPLVLKTPTA DLETLRPQRP DEHAYGITYE QIDDFLEGKP MDDAVAETVL RFYDATRHKR ALPYTMFDWP GHPA

NT Sequence
ATGTCCCGTC CCGATCAGGC CGCCCGCCGG CGTGCGATCG CCGCCGAACT GCACGTGTCG CCCACGTTCG ATGCGCGCGA CGAAGCCGAG CGCCGCATCG GGTTCGTCGC CGATTATCTG CGCACGGCCG GATTGCGGGC CTGCGTGCTG GGCATCAGCG GCGGCATCGA TTCGTCGACG GCGGGCCGGC TCGCGCAACT GGCCGTCGAG CGGCTGCGCG CATCGGGCTA CGACGCGCGC TTCGTCGCGA TGCGGCTGCC GTACGGCGCG CAGCACGACG AAGCGGACGC GCGGCGCGCG CTCGCCTTCG TGCGCGCGGA CGAGACGCTC ACGGTCGACG TGAAGCCGGC CGCCGATGCG ATGCTCGCCG CGCTCGCGGC GGGCGGCCTG GCGTATCTCG ACCACGCACA GCAGGATTTC GTGCTCGGCA ACATCAAGGC GCGCGAGCGG ATGATCGCGC AATACGCGGT GGCGGGCGCG CGGAACGGCG TCGTGATCGG CACCGATCAT GCGGCGGAAT CGGTGATGGG CTTCTTCACG AAGTTCGGCG ACGGCGGCGC GGACGTGCTG CCGCTCGCGG GCCTCACGAA ACGCCGCGTG CGCGCACTCG CGCGCATGCT GGGCGCCGAC GAGCCGCTCG TGCTGAAAAC GCCGACCGCC GATCTCGAAA CGTTGCGTCC GCAACGGCCC GACGAGCACG CGTACGGCAT CACGTACGAG CAGATCGACG ATTTTCTCGA AGGCAAGCCG ATGGACGACG CGGTCGCCGA GACGGTGCTG CGCTTCTATG ACGCGACACG CCACAAGCGC GCGCTGCCCT ATACGATGTT CGACTGGCCG GGCCACCCGG CA

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