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Seattle Structural Genomics Center for Infectious Disease

BupsA.00072.a: RNA methyltransferase, TrmH family, group 2

Target Characteristics

from organism: Burkholderia pseudomallei 1710b
most recent status: in PDB
center reference id: BupsA.00072.a
is community request: False
associated disease: Melioidosis
NIH risk group: 3
is select agent: True
NIH priority
pathogens category:
IIIB

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BupsA.00072.a.A1.GE25038 Full length( BupsA.00072.a ) 1 156 GE25038
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BupsA.00072.a.A1.PW25076 Full length( BupsA.00072.a ) 1 156

Structures

image of structure for 3E5Y
3E5Y
Deposited: 8/14/2008
Determination: XRay
Diffraction Image
Clone: BupsA.00072.a.A1.GE25038
Protein: BupsA.00072.a.A1.PW25076
image of structure for 4KGN
4KGN
Deposited: 4/29/2013
Determination: XRay
Diffraction Image
Clone: BupsA.00072.a.A1.GE25038
Protein: BupsA.00072.a.A1.PW25076

Citations by Others

Structural and Biochemical Insights into the 2O Methylation of Pyrimidines 34 in tRNA
P Pang, X Deng, Z Wang, W Xie - The FEBS Journal, 2017 - Wiley Online Library
PDB: 4KGN

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
OrthoMCL: OG5_132053
PATRIC ID: fig|320372.6.peg.681
RefSeq: YP_332082
UniProt: Q3JWH1

Enzyme & Pathway Information

Pathway Pathway ID EC Number
2.1.1.207

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MFNVVLVEPE IPPNTGNVIR LCANTGARLH LIEPLGFPLD DAKMRRAGLD YHEYAQMRVH RDWDAFVAAE APDPARMFAF TTRGSGRFHD RAFEPGDWFV FGAETRGLAP ALVDRFAPEQ RVRLPMRPGN RSLNLSNTVA VVVFEAWRQA GFEGGA

NT Sequence
ATGTTCAACG TCGTTCTCGT CGAGCCCGAA ATTCCGCCGA ACACCGGCAA CGTGATCCGG CTGTGCGCCA ATACGGGCGC GCGGCTGCAT CTGATCGAGC CGCTCGGCTT TCCGCTCGAC GACGCGAAAA TGCGGCGCGC GGGGCTCGAC TACCACGAAT ACGCGCAGAT GCGCGTGCAT CGCGACTGGG ACGCGTTCGT CGCCGCCGAG GCGCCCGATC CCGCGCGGAT GTTCGCGTTC ACGACGCGCG GCTCGGGCCG CTTTCACGAC CGCGCGTTCG AGCCGGGCGA CTGGTTCGTG TTCGGCGCGG AGACGCGCGG GCTCGCGCCC GCGCTCGTCG ATCGCTTCGC TCCCGAGCAG CGCGTGCGGC TGCCGATGCG GCCGGGCAAT CGCAGCCTCA ATCTGTCGAA CACGGTTGCG GTCGTCGTGT TCGAGGCATG GCGCCAGGCG GGGTTCGAAG GCGGGGCT

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