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Seattle Structural Genomics Center for Infectious Disease

BupsA.00076.a: uracil phosphoribosyltransferase

Target Characteristics

from organism: Burkholderia pseudomallei 1710b
most recent status: in PDB
center reference id: BupsA.00076.a
is community request: False
associated disease: Melioidosis
NIH risk group: 3
is select agent: True
NIH priority
pathogens category:
IIIB

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BupsA.00076.a.A1.GE25041 Full length( BupsA.00076.a ) 1 216 GE25041
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Structures

image of structure for 3DMP
3DMP
Deposited: 7/1/2008
Determination: XRay
Diffraction Image
Clone: BupsA.00076.a.A1.GE25041
Protein: BupsA.00076.a.A1.PW25079

Citations by Others

Enzymatic Production of NonNatural Nucleoside5Monophosphates by a Thermostable Uracil Phosphoribosyltransferase
J del Arco, J Acosta, HM Pereira, A Perona- , 2018 - Wiley Online Library
cited by: 10 others
PDB: 3DMP

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
OrthoMCL: OG5_126624
PATRIC ID: fig|320372.6.peg.1425
RefSeq: YP_332797
UniProt: Q3JUF6

Enzyme & Pathway Information

Pathway Pathway ID EC Number
purine and pyrimidine metabolism P1-PWY 2.4.2.9
salvage pathways of pyrimidine ribonucleotides PWY0-163 2.4.2.9
pyrimidine nucleobases salvage I PWY-7183 2.4.2.9
pyrimidine nucleobases salvage II PWY-7194 2.4.2.9
superpathway of pyrimidine ribonucleosides salvage PWY-7196 2.4.2.9
superpathway of pyrimidine nucleobases salvage PWY-7208 2.4.2.9

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MKQDSRFPNL FILDHPLIQH KLTHMRDKDT STRTFRELLR EITLLMGYEI TRNLPITTKR VETPLVEIDA PVIAGKKLAI VPVLRAGVGM SDGLLELIPS ARVGHIGVYR ADDHRPVEYL VRLPDLEDRI FILCDPMVAT GYSAAHAIDV LKRRGVPGER LMFLALVAAP EGVQVFQDAH PDVKLYVASL DSHLDDHAYI VPGLGDAGDR LFGTKN

NT Sequence
ATGAAACAGG ACAGCCGTTT TCCGAATCTC TTCATCCTCG ACCATCCGCT GATCCAGCAC AAACTCACGC ACATGCGCGA CAAGGACACG TCCACCCGGA CGTTCCGCGA GCTGCTGCGC GAGATCACGC TGCTGATGGG CTACGAGATC ACCCGCAACC TGCCGATCAC GACGAAGCGG GTCGAAACCC CGCTCGTGGA GATCGACGCG CCCGTGATCG CCGGCAAGAA GCTCGCCATC GTGCCCGTGC TGCGCGCGGG CGTCGGGATG TCCGACGGCC TGCTCGAGCT GATTCCGTCG GCGCGCGTCG GCCACATCGG CGTGTACCGC GCCGACGACC ACCGCCCGGT GGAATACCTG GTGCGGCTGC CCGACCTCGA AGACCGGATC TTCATCCTGT GCGACCCGAT GGTCGCGACG GGCTATTCGG CCGCGCACGC AATCGACGTC CTCAAGCGCC GCGGCGTGCC GGGCGAGCGG CTCATGTTCC TCGCGCTCGT CGCCGCGCCC GAAGGCGTGC AGGTGTTCCA GGACGCGCAT CCGGACGTGA AGCTGTATGT CGCGTCGCTC GATTCGCACC TCGACGACCA CGCGTACATC GTCCCCGGCC TGGGCGACGC GGGCGACCGC CTGTTCGGCA CGAAGAAC

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