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Seattle Structural Genomics Center for Infectious Disease

ChtrB.17127.a: Glucose-6-phosphate isomerase (GPI) (EC 5.3.1.9) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI)

Target Characteristics

from organism: Chlamydia trachomatis D/UW-3/Cx
most recent status: in PDB
center reference id: ChtrB.17127.a
is community request: True
associated disease:
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
non-BEI

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
ChtrB.17127.a.B1.GE42414 full length 1 525 GE42414
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
ChtrB.17127.a.B1.PW38526 full length 1 525

Structures

image of structure for 6OTU
6OTU
Deposited: 5/3/2019
Determination: XRay
Diffraction Image
Clone: ChtrB.17127.a.B1.GE42414
Protein: ChtrB.17127.a.B1.PW38526

Molecular models

Method Results
comparative modelling Robetta_82022

External Resources

Resource Reference ID
PATRIC ID: fig|272561.5.peg.407
UniProt: P0CD72

Enzyme & Pathway Information

Pathway Pathway ID EC Number
homolactic fermentation ANAEROFRUCAT-PWY 5.3.1.9
glycolysis III (from glucose) ANAGLYCOLYSIS-PWY 5.3.1.9
colanic acid building blocks biosynthesis COLANSYN-PWY 5.3.1.9
gluconeogenesis I GLUCONEO-PWY 5.3.1.9
glycolysis I (from glucose 6-phosphate) GLYCOLYSIS 5.3.1.9
superpathway of glycolysis and the Entner-Doudoroff pathway GLYCOLYSIS-E-D 5.3.1.9
superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass GLYCOLYSIS-TCA-GLYOX-BYPASS 5.3.1.9
O-antigen building blocks biosynthesis (E. coli) OANTIGEN-PWY 5.3.1.9
heterolactic fermentation P122-PWY 5.3.1.9
Bifidobacterium shunt P124-PWY 5.3.1.9
glycolysis V (Pyrococcus) P341-PWY 5.3.1.9
sucrose degradation II (sucrose synthase) PWY-3801 5.3.1.9
D-sorbitol biosynthesis I PWY-5054 5.3.1.9
sucrose degradation IV (sucrose phosphorylase) PWY-5384 5.3.1.9
UDP-N-acetyl-D-galactosamine biosynthesis II PWY-5514 5.3.1.9
GDP-mannose biosynthesis PWY-5659 5.3.1.9
gluconeogenesis II (Methanobacterium thermoautotrophicum) PWY-6142 5.3.1.9
Methanobacterium thermoautotrophicum biosynthetic metabolism PWY-6146 5.3.1.9
sucrose degradation III (sucrose invertase) PWY-621 5.3.1.9
starch biosynthesis PWY-622 5.3.1.9
superpathway of mycolyl-arabinogalactan-peptidoglycan complex biosynthesis PWY-6404 5.3.1.9
gluconeogenesis III PWY66-399 5.3.1.9
glycolysis VI (metazoan) PWY66-400 5.3.1.9
chitin biosynthesis PWY-6981 5.3.1.9
1,5-anhydrofructose degradation PWY-6992 5.3.1.9
sucrose biosynthesis II PWY-7238 5.3.1.9
superpathway of GDP-mannose-derived O-antigen building blocks biosynthesis PWY-7323 5.3.1.9
superpathway of UDP-N-acetylglucosamine-derived O-antigen building blocks biosynthesis PWY-7332 5.3.1.9
superpathway of anaerobic sucrose degradation PWY-7345 5.3.1.9
sucrose biosynthesis III PWY-7347 5.3.1.9
1,3-propanediol biosynthesis (engineered) PWY-7385 5.3.1.9
formaldehyde oxidation I RUMP-PWY 5.3.1.9
sucrose biosynthesis I (from photosynthesis) SUCSYN-PWY 5.3.1.9
UDP-N-acetyl-D-glucosamine biosynthesis II UDPNACETYLGALSYN-PWY 5.3.1.9
UDP-N-acetyl-D-glucosamine biosynthesis I UDPNAGSYN-PWY 5.3.1.9

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MMGKGFLDCE SLVALQEMAL HPIDLTASGC LSEERIQKNS LSAEGFTYSY ATERVDDRCL EALQGLTEER ELIKQMECMQ QGAIMNRIEG FQSESRPVLH TATRAWVRDQ DLHEEAAAIA RHSKEEALRL AEFLYIARAK FSTLVQMGIG GSELGPKAMY FAMQGSCPSD KRIFFVSNID PDNAAEVLRE IDLEQTLVVV VSKSGTTLEP AANEELFRQA YQNKGLSIAE HFVAVTSQGS PMDDKSRYLE VFHLWDSIGG RFSATSMVGG VVLGFAFGYE AFIEFLQGAA AIDAHALTPK MRENLPLLSA MLGVWNRNLL GYPTTAVIPY STGLKYFTAH LQQCGMESNG KSISREGKEI SFRTSPIIWG DVGTNCQHSF FQSLHQGTDI VPVEFIGFLH NQRGLDCVLS GSSSSQKLFA NLVAQSLALA QGRDNANSNK RFKGNRPSSI LVAQQLSPRI AGSLLAFYEH KFAFQGFCWG INSFDQEGVS LGKELATQII GIMSGNAPVE FSEARGMLRL FNVLT

NT Sequence
atgatgggta aaggtttttt agattgtgag tcattagttg ctttgcaaga gatggctttg catccgattg atttgactgc atcaggatgc ttatctgaag agcgtattca gaaaaactct ttatctgcag aaggatttac ctatagttat gctacggaac gtgtagatga tcgctgctta gaggctttac aaggacttac tgaagagagg gaattgatca aacagatgga gtgtatgcaa caaggcgcca tcatgaatcg tatagaaggt tttcagagcg aatctcgccc tgtattgcat acggcaacac gcgcttgggt tcgagatcaa gatcttcatg aagaagctgc tgcgatagca agacactcta aggaggaagc tcttcgtctt gcagagtttc tgtatatagc tcgtgctaaa ttttctacgc ttgtacagat gggtattggg ggctcggagt tgggccctaa agctatgtat tttgctatgc aaggctcttg cccatctgat aagagaatct tttttgtctc caatattgat ccggataatg ctgcagaagt attacgggag atagatttgg agcaaacact ggttgttgtg gtttctaagt caggaacaac tttagagcct gcagcaaatg aagagctgtt cagacaggct tatcaaaata aaggtttatc tattgcagag cattttgtag cggtaacttc tcaaggcagc cctatggatg ataagagtcg ttatctagaa gtattccatc tttgggatag tattggcgga agattttcag ctacatccat ggtaggagga gttgtattag gttttgcttt cggttacgaa gcttttatag agtttttgca aggagcagct gctatcgatg ctcatgcgct gactccaaaa atgagagaga atcttcctct tctatctgcg atgcttggag tttggaatcg taatctgtta gggtatccta caacagcagt gattccttat tcgacaggat tgaaatattt tacagcgcat ttacaacagt gtggaatgga atccaatgga aaaagtattt cgagagaagg gaaggagatt agttttagga cttcacccat tatttggggc gatgtgggga caaactgtca gcattctttt ttccaaagtc ttcatcaagg aacagatatt gttcccgtag agttcattgg atttttgcat aaccaacgag ggctagattg tgtattatca ggaagctcat catctcaaaa gctctttgca aaccttgttg ctcaatcttt agctttagct cagggtagag ataatgcgaa ctcgaataag aggtttaaag ggaacagacc ttcttcgata ttggtagcgc aacagctttc tcctcgtatt gctggtagtt tattggcttt ttatgagcat aaatttgcat ttcaagggtt ttgctgggga atcaattctt ttgaccaaga aggggtttca ttagggaaag aattggcaac gcaaattata ggcatcatgt cggggaatgc tcctgtagag ttttccgaag ctcgaggtat gttaagactt tttaacgttt taacataa

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