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Seattle Structural Genomics Center for Infectious Disease

ChtrB.18708.a: Isoleucine--tRNA ligase (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS)

Target Characteristics

from organism: Chlamydia trachomatis D/UW-3/Cx
most recent status: cloned
center reference id: ChtrB.18708.a
is community request: True
associated disease:
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
non-BEI

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Molecular models

Method Results
comparative modelling Robetta_82006

External Resources

Resource Reference ID
PATRIC ID: fig|272561.5.peg.24
UniProt: O84022

Enzyme & Pathway Information

Pathway Pathway ID EC Number
tRNA charging TRNA-CHARGING-PWY 6.1.1.5

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MDNEDKISIS AKEEKILSFW KEQDIFQKTL DNREGCPTFS FYDGPPFATG LPHYGHLLAG TIKDVVCRYA SMDGHYVPRR FGWDCHGVPV EYEVEKSLGL TEPGAIERFG VANFNEECRK IVFRYADEWK YFVDRIGRWV DFSATWRTMD LSFMESVWWV FRSLYDQGLV YEGTKVVPFS TKLGTPLSNF EAGQNYKEVD DPSVVVKFAL QDNQGFLLAW TTTPWTLVSN MALAVHPELT YVRIKDKESG DEYILGQESL PRWFPDRESY EWIGQLSGKS LVGQSYEPLF PYFQDKKELE AFRILPADFI EESEGTGIVH MAPAFGEADF FACQEHNVPL VCPVDNQGCY TAEVKDFVGE YIKSADKGIA RRLKNENKLF YQGTVRHRYP FCWRTDSPLI YKAVNSWFVA VEKVKSKMLK ANESIHWTPE HIKQGRFGKW LEGARDWAIS RNRYWGTPIP IWRSDDGELL VIGSIQELEA LSGQKIVDLH RHFIDEIEIN QNGKSFRRIP YVFDCWFDSG AMPYAQNHYP FERAEETEAC FPADFIAEGL DQTRGWFYTL TVIAAALFDQ PAFKNVIVNG IILAEDGNKM SKRLNNYPSP KMIMDAYGAD ALRLYLLNSV VVKAEDLRFS DKGVESVLKQ VLLPLSNALA FYKTYAELYG FDPKETDNIE LAEIDRWILS SLYSLVGKTR ESMSQYDLHA AVNPFVDFIE DLTNWYIRRS RRRFWDAEDS ADRRAAFSTL YEVLVVFSKV IAPFIPFIAE DMYQQLRGET DPESVHLCDF PHVVLEKILP DLERKMQDIR EIVALGHSLR KEHKLKVRQP LQNVYIVGSK ERKEALAQVG SLIGEELNVK DVHFCSETPE YVTTLIKPNF RTLGKKVGNR LPEIQRALAG LPQEQIQAFM HKGQMVVSLG EETISLDKED ITVSWASAEG FVARSSASFV AVLDCQLTEP LIMEGIAREL VNKINTMRRN RKLHVSDRIA IRLHAPVIVQ EAFALHKEYI CEETLTTSVS VIDYKEGEEW DINGHAVSFV LERVER

NT Sequence
atggataacg aagataagat tagtatttcc gccaaagagg aaaagattct atctttttgg aaagagcaag atatttttca aaaaacttta gacaatcgag agggctgccc cactttttct ttttatgacg ggcctccatt tgctacaggc ttaccgcatt atggccacct gttagcaggt acaataaaag atgttgtatg tcgttatgcg tcgatggatg ggcattatgt gccccggcgt tttggctggg attgtcatgg ggtgccagtc gaatacgaag tagagaaatc tttaggtctt accgagccag gagctattga gcgtttcggt gtggcgaatt ttaacgaaga atgtcgcaag attgttttcc gatacgcgga tgaatggaaa tattttgtgg ataggatcgg ccgatgggta gatttttctg caacatggag gactatggac ctatctttca tggagagtgt ctggtgggta ttccgctctc tctatgatca aggacttgtg tatgagggga ccaaagtagt tcctttttct accaagctag gtaccccgct atccaatttc gaagctggcc aaaactataa ggaagtagac gacccttctg tcgttgtaaa atttgctttg caagacaatc aaggctttct tctagcatgg accacaactc cttggactct tgtttcaaat atggcgctag ctgtgcatcc tgagctcacc tatgtccgta ttaaagacaa agaatcagga gacgaatata tcctgggaca ggaaagtttg cctcgttggt tcccagatcg agaatcttat gaatggatag gacaattgtc tggaaagagt cttgttggac aaagttacga accgcttttc ccttatttcc aagataaaaa ggagttagag gcttttcgta ttcttcctgc agattttatt gaggaaagtg aggggacggg tattgttcat atggcaccag cttttggaga agctgacttt tttgcttgcc aggaacataa cgtacctcta gtgtgccctg ttgataatca ggggtgttat accgctgagg tgaaggattt tgtcggcgaa tatattaagt ctgctgacaa aggcatcgct cgtcgattga agaacgaaaa taaactgttc tatcaaggta cagttcgtca ccgctatccg ttttgttgga gaactgactc tcctttaatt tacaaagcag tgaattcttg gttcgttgct gtagaaaagg taaagagtaa gatgttaaaa gccaatgaat ccattcattg gactcctgag catatcaaac aaggacgctt tggtaagtgg ttagagggag ctcgtgactg ggctatcagt agaaatcgtt attgggggac tcctatacct atttggcgta gtgacgatgg agagcttttg gtcataggat ctatccagga actggaggca ttatctggac agaagattgt agatttgcat cgccatttta ttgatgagat agaaattaac cagaacggga aatctttccg aagaatccct tatgttttcg attgttggtt tgattctgga gctatgccat atgctcagaa tcattaccct tttgaaagag cagaagaaac ggaggcttgc ttcccagctg actttattgc tgaaggacta gatcagactc gaggttggtt ctatacgtta accgttattg ctgcagcttt attcgatcag cccgctttta aaaatgtaat tgtaaatggg attattcttg cggaagacgg aaataaaatg tcgaagcggt tgaataatta tcctagtcca aaaatgatta tggacgcgta tggagcagat gctttgcggc tgtatttgtt gaatagcgtg gtcgttaaag ctgaagatct tcgcttttcc gataaagggg tagagtctgt gcttaagcaa gttctattgc cgttgtctaa tgctttggct ttctataaga cttatgcgga attgtatggt tttgatccta aagaaacaga caatatagaa cttgctgaaa tagaccgctg gattctttct tctctataca gtttggtagg gaaaactcga gaaagtatgt cgcaatatga tttacatgct gctgtaaatc cttttgtgga tttcattgaa gatttaacta actggtatat tcgtaggtcg cggcgacgtt tttgggatgc cgaggattct gcagatcgac gggcagcatt ctctacactt tatgaagtgt tggtagtctt ttctaaagtc attgcgccat tcattccttt tattgcagaa gatatgtacc agcaattacg aggagaaacg gatcccgagt ctgtgcactt atgtgatttt cctcacgttg tcctagaaaa gattcttcct gatttggaaa ggaaaatgca ggatattcga gagattgtag ctctagggca ttctttgcgt aaggagcata aactgaaagt acgtcaacct cttcaaaacg tgtatattgt aggaagcaag gagagaaagg aggctttagc tcaagttgga tccttgattg gagaagagct taatgtgaaa gacgtacatt tttgttcaga aactccggag tatgtaacca ctttgattaa gcctaatttc cgaaccttag ggaagaaggt aggtaatcgt cttccagaaa ttcaaagagc tctagcagga ttgcctcaag agcaaattca ggcttttatg cacaaagggc agatggttgt ttctctagga gaagagacca tttctttaga taaagaggac attacagttt cttgggcatc ggctgaagga tttgtagcga gaagctcagc ttcttttgta gcagtactgg attgtcagtt aacagagcct ttaattatgg aaggtatagc cagagagttg gttaataaga tcaacactat gcgaagaaat aggaaattac acgtttctga tcgcattgct atacgtttac atgcccctgt tatcgttcag gaagcgttcg ctttacacaa agagtatatt tgtgaagaga cattaaccac ttccgtttct gtgatcgatt ataaagaagg ggaagagtgg gatattaacg gtcacgcagt gtccttcgtt ctggagcgag ttgagcgttg a

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