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Seattle Structural Genomics Center for Infectious Disease

CoimA.00629.a: Acetyl-coenzyme A synthetase (EC 6.2.1.1)

Target Characteristics

from organism: Coccidioides immitis RS
most recent status: purified
center reference id: CoimA.00629.a
is community request: True
associated disease: California disease, Desert rheumatism, San Joaquin valley fever, Valley fever
NIH risk group: 2
is select agent: True
NIH priority
pathogens category:
II

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
CoimA.00629.a.FS11.GE00456 full length 2 692 GE00456
CoimA.00629.a.HA11.GE00476 full length 39 666 GE00476
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
CoimA.00629.a.FS11.PD00400 full length 2 692

External Resources

Resource Reference ID
EuPathDB: FungiDB:CIMG_01642
RefSeq: XP_001247871.2
UniProt: J3KJM0

Enzyme & Pathway Information

Pathway Pathway ID EC Number
superpathway of acetate utilization and formation ACETATEUTIL-PWY 6.2.1.1
acetate conversion to acetyl-CoA PWY0-1313 6.2.1.1
L-isoleucine biosynthesis V PWY-5108 6.2.1.1
lupulone and humulone biosynthesis PWY-5132 6.2.1.1
colupulone and cohumulone biosynthesis PWY-5133 6.2.1.1
superpathway of bitter acids biosynthesis PWY-5134 6.2.1.1
ethanol degradation III PWY66-161 6.2.1.1
ethanol degradation IV PWY66-162 6.2.1.1
ethanol degradation II PWY66-21 6.2.1.1
cis-genanyl-CoA degradation PWY-6672 6.2.1.1
chitin degradation to ethanol PWY-7118 6.2.1.1
adlupulone and adhumulone biosynthesis PWY-7857 6.2.1.1

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSETPAEPKL PVVVEAHQVD TFDVPGVFYE NHPHEPHLSG MNEYNQLYQQ SINDPDTFWA RMARDLITFE KDFDKTHIGT LEGGDNAWFV GGRLNASFNC VDRHAMRDPN KVAIIYEADE PGHGRSITYA ELLKEVSRLA WVMKSQGVRK GDTVAIYLPM IPEAIFALLA CARIGAIHSV VFAGFSSDSL RDRTLDARSK FIITTDEGKR GGKVIGTKKI VDEALKQCPD VTNCLVFKRT GADVPWTKGR DLWWHEEVDK YPNYLPAESM DSEDPLFLLY TSGSTGKPKG VMHTTAGYLV GAAATGKYVF DIHPADRFFC GGDVGWITGH TYVVYAPLLL GCTTVVFEST PAYPNFSRYW DVIEKHKVTQ FYVAPTALRL LKRAGDHHIN HEMKDLRILG SVGEPIAAEV WKWYHEVVGK RQAHIVDTYW QTETGSHVIT PLGGITPTKP GSASLPFFGI DPVILDPVTG AEIPGNDVEG ILAFRKPWPS MARTVWGDHK RYMDTYLNVY KGFYFTGDGA GRDHEGYYWI RGRVDDVVNV SGHRLSTAEI EAALIEHHCV AEAAVVGVPD PLTGQAVHAF VALKSGNDNR EQLQKELIMQ VRKSIGPFAA PKVVFVIDDL PKTRSGKIMR RILRKILSGE EDSLGDISTL SDPSVVNKII DTFHEWKKAM AAAAAAAAAV SATAPPNSTT G

NT Sequence
atgtctgaga cgcctgctga accaaagctc ccagtggtcg tggaggccca ccaggtcgat accttcgacg ttccaggagt attctatgag aaccaccccc atgaaccaca cctgagtggc atgaatgaat ataaccagct ctaccaacaa tctatcaatg atcctgacac cttctgggcg cgcatggcgc gcgatcttat tactttcgaa aaggatttcg acaagactca cattgggacc ctcgaaggcg gggataatgc ctggtttgtc ggtggtcgat taaatgcgtc cttcaactgc gttgatcgcc atgcaatgcg tgacccgaac aaggttgcaa tcatctatga agccgatgag cctggccacg gccgcagtat tacctatgca gaattgttga aggaagtctc cagactggcc tgggtgatga agagccaagg tgttaggaaa ggcgataccg tcgcgattta tcttcctatg atccctgagg ccatcttcgc gcttcttgcc tgtgcgcgta ttggcgccat tcattctgtg gtctttgcgg gcttctcttc cgattccctg cgtgatcgta ccctggatgc ccggtcaaaa ttcattatca caaccgatga gggaaagcgt ggtggaaaag tcattgggac taagaaaatt gttgatgaag ctttaaaaca atgcccagat gttaccaatt gccttgtttt caagagaact ggggccgacg tgccttggac caaaggccgt gacctgtggt ggcatgaaga ggttgataaa tatccaaatt atctgcctgc tgagtcaatg gactctgaag acccgctttt ccttctctac acatctggct ccaccgggaa accaaagggt gttatgcaca caactgctgg ctaccttgtt ggagcagctg caactggaaa atatgtcttt gatattcacc cagctgaccg ttttttttgc ggtggtgatg ttggatggat tactggacat acttatgttg tctatgctcc attgcttttg gggtgcacta ctgtggtgtt tgaaagcaca ccagcgtatc ccaatttctc gcgatactgg gatgttattg agaagcacaa ggtcacccag ttttatgtag cacctacggc tttgcgcctg ttgaaacgtg caggtgacca ccacataaat catgaaatga aggatttacg tattctgggc tctgttggtg aaccaatcgc tgcagaggtt tggaagtggt accatgaggt tgttgggaaa agacaagccc atattgttga tacatactgg caaaccgaga ccggctccca tgttatcacc cccttgggtg gtattactcc aactaaacca ggaagtgctt cgcttccatt ctttggtatt gaccctgtca ttctggatcc agttacaggt gcagagattc cgggaaatga tgtggaggga atccttgctt tcagaaagcc atggccaagc atggctcgca ctgtatgggg cgatcataaa cgatacatgg acacctatct caatgtttat aaaggctttt atttcactgg tgatggcgct ggacgtgatc atgaaggcta ttactggatt agaggtcgtg tggatgatgt tgtgaacgtc tctggccacc gcctttcaac tgcagagatc gaagcagcac ttatcgaaca ccactgtgtt gcagaagccg cggttgttgg agttcctgat ccgctaactg gacaagctgt gcatgcattt gtggccctga agagtggaaa tgacaataga gaacagctcc aaaaggagtt gattatgcaa gtccgcaaat cgattggacc atttgctgcc ccgaaggttg tgtttgtgat cgatgacctt ccgaaaacac gtagcgggaa gatcatgaga cgcatcttgc gaaagattct gagcggtgag gaggacagtc ttggtgacat ttcaacgctc tcggatccta gcgtcgtgaa taaaatcatc gacactttcc acgaatggaa aaaagctatg gcagctgccg ccgccgctgc tgctgctgtg tcagcaaccg cgccaccaaa cagcacaacc ggttaa

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