NIAID Emerging and Re-emerging Infectious Diseases NIAID Bioinformatics Resource Centers NIAID Structural Genomic Centers Center for Structural Genomics of Infectious Disease
Seattle Structural Genomics Center for Infectious Disease

CrneC.01291.b: Adenylate kinase (EC 2.7.4.3) (ATP-AMP transphosphorylase) (ATP:AMP phosphotransferase) (Adenylate kinase cytosolic and mitochondrial) (Adenylate monophosphate kinase)

Target Characteristics

from organism: Cryptococcus neoformans var. grubii serotype A (H99 / ATCC 208821 / CBS 10515 / FGSC 9487)
most recent status: purified
center reference id: CrneC.01291.b
is community request: True
associated disease: Pneumonia-like illness
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
unclassified

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
CrneC.01291.b.B1.GE41328 full length 1 269 GE41328
CrneC.01291.b.B2.GE41329 Truncation 1 54 269 GE41329
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
CrneC.01291.b.B2.PW38303 Truncation 1 54 269
CrneC.01291.b.B2.PW38304 Truncation 1 54 269

External Resources

Resource Reference ID
EuPathDB: FungiDB:CNAG_02007
UniProt: J9VVB2

Enzyme & Pathway Information

Pathway Pathway ID EC Number
superpathway of purine nucleotides de novo biosynthesis II DENOVOPURINE2-PWY 2.7.4.3
purine and pyrimidine metabolism P1-PWY 2.7.4.3
superpathway of histidine, purine, and pyrimidine biosynthesis PRPP-PWY 2.7.4.3
superpathway of adenosine nucleotides de novo biosynthesis II PWY-6126 2.7.4.3
superpathway of purine nucleotide salvage PWY66-409 2.7.4.3
adenosine ribonucleotides de novo biosynthesis PWY-7219 2.7.4.3
superpathway of adenosine nucleotides de novo biosynthesis I PWY-7229 2.7.4.3
superpathway of purine nucleotides de novo biosynthesis I PWY-841 2.7.4.3

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSGNPEVEYL KSLVSQLQDK IHQLEKSTST SVSNTISSVT SALSPSSSSK PPRMVLIGPP GAGKGTQAPN ISSKYCICHL ATGDMLREQV SKQTELGKAA KQIMDQGGLV SDEIMVGMIK QELEKNAECK HGFILDGFPR TVPQASKLDA MLAERKQAID HAIELKIPDA LLISRITGRL VHPASGRSYH REFNPPKKPM TDDITGEPLI QRSDDNVGTL RKRLDTYHAQ TGPVVDYYKG TGVWTPVDAA QSPKLVWASI SSILESKKN

NT Sequence
atgtctggca accctgaagt tgaatatttg aagtctcttg tctctcagct ccaagacaag atccatcaac tcgagaagtc tacctccacc tccgtctcca acaccatctc ctccgtcacc tccgccctct ctccctcttc ctccagcaag cctccccgaa tggtcctcat cggccctccc ggtgctggta agggtactca agcgcccaac atctctagca aatactgcat ctgtcacctc gctactggtg acatgttgag ggagcaagtt tccaagcaga ccgaattggg taaggctgct aaacagatta tggaccaggg cggtttggtt tccgatgaga ttatggttgg catgatcaag caggagttgg agaagaacgc cgagtgcaag catggcttca tcctcgacgg cttcccccgt accgtccccc aggcttccaa gctcgatgcc atgcttgccg agcgcaaaca agctatcgac cacgctatcg agctcaagat ccccgacgcc ttgttgatct cccgaattac tggtcgattg gtccaccccg cgagcggtag gagttaccac agggaattca acccccctaa gaagcccatg actgatgaca tcaccggcga gcccctcata caacgttccg acgacaacgt cggtaccctc aggaagcgat tggacactta ccacgcccag actggccccg ttgttgacta ttacaagggt actggtgttt ggactcctgt cgatgccgct cagagcccca agttggtctg ggctagtatc agcagtatct tggaaagcaa gaagaactaa

© 2019 Seattle Children's Research Institute. All rights reserved.