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Seattle Structural Genomics Center for Infectious Disease

CrneC.19342.a: 1-phosphatidylinositol-3-phosphate 5-kinase

Target Characteristics

from organism: Cryptococcus neoformans var. grubii serotype A (H99 / ATCC 208821 / CBS 10515 / FGSC 9487)
most recent status: expressed
center reference id: CrneC.19342.a
is community request: True
associated disease: Pneumonia-like illness
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
unclassified

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
CrneC.19342.a.B2.GE40991 kinase domain 2113 2415 GE40991
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

External Resources

Resource Reference ID
EuPathDB: FungiDB:CNAG_01209
UniProt: J9VQS3

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MPSSFSEHSI PPSSHLTTFP NPFQDEPEQG ILPTFLSKVK QTFTSGISQP PTQNSHASSD RLPHLIEGEN KIAHDGDSNL VAPPREGGQT EAQAIAEAVM RNRIQTAAQG ALPNSAAEQQ QRMHGQSAGS IGAVVATSAE ALPPTQSTAH PSNLSIHTTH GQPLNQPIGP VNTFGSSNPH LPVPASVASS QVSISGQKRA VAPGGPQWRP SGVAPAQVTV SPVTTTVQTA SKEPISSPAR PIRFPSTKPP HRGNVNLQSS ISSSSRAPTP LPHHIHTNLL STGQNKRHRR SSVATLPDSP SSLSISGMIA ANAELTQSHS YVPGFPLAQD DTRSVRSMGA VKRLNSVSRI IKRMKGDGLS KQYWMADEHC KECYDCKSIF TAWRRKHHCR ICGQIFCSRC ASNIIGARRF GQEGVVRVCN LCLKIMEEYK DDDDDDRRSI NSFSTSVHRY PTISDRAFLN TAMSPEMPYA KSPFAASQLF SSHPNDSLMA IDEASVPIRW EDGRLDTERA FLLNEVGRSP TSDRDDHIWA GRPPTVAPFR RPLELDQKVA ADQGEADGDG RVSTPVLETS GSALHATYRD ATSFPFPRTN TMSTDDDVER VPLSREDSGH PLIGLKTRMN QAVLTALLDS EKSEGLWRAR SHSFAHQPEM LTGASLQHFK LMLSQAIARA ELPKADEWHR ILTSLILKVP LNLQPNVRAG DDIDVRAYVK IKKVPGGKIS DSEYVDGIVI TKNVAHKAMS RRLVNPRIMV VTFPLDYHRV DNQFMSLDPI LAQEKDYLRL LTKRIVDARP HIVLAQSSVS RIALDYLLEA NVALARSVKT SAIQQVARCT QADVVASMDR LVLEPRMGRC GEFRIQSFDH ELIPGRRKTL MRFEGASKEQ GCTIILRGAD LPTLRKVKVI TDFMALVAYH LRNEMIMYND EHNIPPPKPV LPTEYRELLD LLDSDKPPAE GSPSCDTPSQ LSHSTATLKP SLKPITPPDD IEFISESSST PTPNQNPIQS DDKQLEKRDA LEVTRQIAKS LEPYLTVVLS SSAAIMFPPP AILAKMVELD RRLSELRVNR DEAEAAQILE EETKVAEVPK DSAPNAGGTD SETVSLAPTS ISEATRSSSE VPISDAMSVY PTTSTSKPPI RDPYHILRKP QEVSQESALA QVEHAHQEQI RLWRWYTRRF AEELRPENYQ GIVYLSSLGC EGAEKPCMEP SLQRIDYYQP GDQTVGQFLE NLALVAPDQC TSKNCERLLL FHYHLLVHGQ RRLQIAVDQF PCPSPGHEDQ IITWSYCRQC ATPSPTTIMR EETWKMSWGA YLQQCFYPPE IRAGFSCPHD AFRDQIRYYA HRNLAIRIHN EQIDLFEPVR PSIKLQVRAE TKVVLKNREY DSALAKIYAF FDSVASRLRT IDVEDVQSDK VSRLNTTVES MLVRAASDRE EITNLLNRTY KLTPVTDVLS LNVVLRALQD KVVQWDVDFA DIEKAFMPTE KDLRKMTASH LKRLFANQDA PGSLERSALT GTPSVVSEEH ETKDDVALTH VPSDKQTTII GLSSDTNTDG AEDIATTKFD GDDASITPTA GILQPMSNPY SRSVRSGSKE TDDDSDSTVF ATHEDLVGKS GGGKTTIEPS TENDTSQFVS RLPRRAAPAP SIADLVQRFN ESTQLALPKL TRSPERSRSA GGSYRQSPRQ HPRHDISDSD HSSRNRPKLR RGKTEQPSHR QRDASRPGLM SDGDRSYATN ASRISSSSHL HRSVGESKNN DYLTVRHSIG SRAPSYTSKV SPRSGRASPK LRYPVVTHVQ SLFDLEEGKP RVAGKGKSPR RPESDTITPI AGKNAGRRSQ SGTSRVNSIA RHFDRLSREA EKERQKRISI VRGKRARPVS VTKAKVQVFD NLRDAFRDEF DTDSSEADNE EDELGSDDSL GSADELVSRT KAESFSNKSP LIRQTGTSSV PITTSPSLLP GPSLSNDDLV TTSPPIAYEA TTSILSDSKS EKSFTDRLKI ELPSFETSAP LPSHPATPQV HTDTTTADEA LGAVSASQTS DVETSTANEK SSLLKSLSGL WAFRAADFAP LEYPLSASEH IFADSKVIIR ETEPTSIIAF TLSSKTYRDN SKAWSASRQK EGRFDTFMPE EAMGTNHPAA WDAVSLEDVD EAARLERGTH MKYDFESGAS TIFCRIFFAE QFAALRKSCN CEDSFVESLA RCIQFDASGG KSGSAFLKSR DDRFIAKEIT RYEMDALTKF APAYFDYTRK AFQGQRPTVL AKIYGFFKIG FNNAITGKAM KMNVLIMENL FYERRFAKIY DLKGSTRNRL IQPTGRINEV LLDENLMEIV YKHPLYLREQ SKRILRTALF NDTLFLSNLN VMDYSLVVGV DTDKHELVVG IVDYIRTFTW DKKLESWVKD LGAGGKGEPT IVTPKQYKLR FRTAMERFYF PSVPDRWTIV GPDETQIEED GPGAGMTG

NT Sequence
atgccttcct ccttctcaga gcattccatc ccaccctcat ctcacctcac caccttccca aacccctttc aggatgaacc agagcaagga atacttccaa cattcctttc aaaagtgaag cagacattta catcaggcat atcccaacct cctacccaaa attcccatgc aagctccgac cgactacctc acttgataga aggtgaaaac aaaatcgctc atgacggaga ttcgaatctc gtcgctccac ctagggaagg cggccaaaca gaggcgcagg ccattgcaga ggcagtcatg aggaatagga tccagacggc tgctcaaggt gcacttccga actcagcagc tgagcaacag cagcgcatgc acgggcagtc ggctggatcg atcggcgccg tcgtagctac atccgcagaa gcgctgcccc caacacagtc tactgcccat ccctcaaact tgtctatcca taccacgcat ggccagcccc tgaatcagcc tatcggccct gttaacactt tcggtagctc aaatcctcac ctgcccgtcc ccgcctctgt tgcttcgtcc caagtctcca tttcagggca gaagcgagct gtcgctcctg gagggccaca gtggcgccca tccggtgtcg ctcctgcaca ggtcactgtt tcgcccgtga cgacgacagt acagactgcg agcaaggaac ctatttcatc tcctgctaga ccgattcgct ttccgagtac caaacctcca catcgaggta atgtcaacct tcaaagctct atatcctcat cctcgcgtgc tccaaccccg ctacctcacc acattcacac caatcttcta tcgacaggcc aaaataaacg ccatcgtaga tcatctgttg cgacccttcc tgattcacct tcttcccttt ccatttccgg tatgatagct gccaacgctg aattaactca gagtcatagc tacgttcctg gattcccttt agcacaagat gacaccagaa gcgtgaggag catgggggcc gtcaagaggc tgaacagtgt cagcaggatt atcaaaagga tgaagggaga cggcctaagt aagcaatact ggatggctga cgagcattgc aaggaatgtt acgactgcaa atccattttc acggcatggc gaaggaagca tcattgccgg atatgcggtc agatattctg ctctcgctgt gcatccaata tcatcggtgc tcgtcgtttc ggacaggaag gagttgtaag agtttgcaat ctttgcctca agattatgga agagtacaag gacgacgacg acgatgaccg tcggtcaatc aattcattct ctacgtccgt tcaccggtat ccgactatat ccgaccgagc atttctcaac acggcaatgt ccccagagat gccttatgcc aaatccccct ttgccgcaag ccaactattt agttcccatc caaacgactc acttatggcc attgatgagg cctcggttcc cattcgatgg gaggatggtc gtctagatac ggagagagcc ttccttctca atgaggttgg caggtcacca acatccgata gagatgacca tatatgggca ggaagaccgc caactgtcgc gcctttcagg agacccctag agcttgacca aaaagtcgct gccgaccagg gagaagctga cggagatggt cgcgtcagta ctcctgtgtt ggaaacctca ggttccgcgt tacatgctac gtatagagat gcgacaagct ttccttttcc taggacaaat accatgtcca cagacgatga tgtagaaaga gtaccactga gtcgcgaaga ctcaggtcat cctctcattg gtttgaagac gaggatgaat caggcagtcc ttactgcact gttggattca gaaaagtcgg agggactctg gagagcgagg tcacactctt tcgcacacca acccgaaatg ttaacaggcg caagcctcca acatttcaaa ctcatgcttt cacaagctat cgcacgtgcc gaacttccca aagccgacga atggcatcga attctgacca gtctcatcct caaagtacct ctcaacttac agcccaatgt acgcgctggg gatgatattg acgttcgggc gtatgtcaaa ataaaaaagg tcccaggtgg gaaaatcagt gactcggagt acgtagacgg aatcgtcata accaaaaatg tggcccacaa agccatgtcc aggagacttg ttaacccgcg cataatggtg gtcaccttcc ctttagatta tcacagggtt gataatcagt tcatgtcttt ggatccaatt ctcgctcagg aaaaagatta tttacggctg ctgacgaaac gcatcgttga tgcccgacct cacatcgtat tggcccagtc ctctgtttca cgaatcgcac tcgactacct gctagaggct aacgtcgcgc ttgctcgcag cgtcaaaact tctgctatcc agcaagtggc cagatgtact caagcggacg ttgttgcttc gatggatcga ctcgtccttg aaccaaggat gggccgatgt ggagagttta ggattcaatc ttttgatcat gagcttatac cgggtagaag gaaaacttta atgaggtttg aaggggcaag caaggagcaa ggctgcacga tcatattgcg tggtgctgat ttgccaactt tacgcaaggt taaagtgatc acagatttca tggcgctcgt ggcatatcat ctgagaaacg agatgataat gtacaacgac gaacacaaca ttccgccacc taagcctgtg ctcccaacgg agtaccgcga gcttctagac cttctcgact ccgataaacc tcctgctgaa ggtagtcctt cttgtgacac accttcgcaa ctttctcatt ctaccgccac ccttaaaccc agccttaaac ccatcactcc ccctgatgat atcgagttca tatccgaatc ttcttcaact cctacgccaa atcaaaatcc tatccaatct gatgacaaac aacttgagaa gcgtgatgct ctggaagtga cgagacagat tgccaagtca ctcgagccct atctgacagt cgttttgtct tcttccgcag caataatgtt tccccctcct gccattttgg caaaaatggt tgagcttgat cggagattgt cagagctgag agtgaacaga gatgaagcgg aggcagcgca gatattagaa gaggaaacaa aagtggcaga ggtaccaaaa gacagtgctc ctaacgccgg aggtaccgat tccgagacag tctcattagc cccaacatcg atctctgaag cgactagatc ctcctctgaa gtgccgatta gtgatgctat gagcgtctat cccacgacat ctacaagcaa accaccaata cgagatcctt atcacattct gcggaagccc caagaagtat cccaagaaag tgcgctggcg caagtagaac atgcccatca agaacagatc agactttggc gatggtacac gcgtagattt gcagaagaac tccggcctga aaactatcaa ggcattgttt acttgtcatc attgggatgt gaaggtgccg aaaaaccatg tatggagccg tctcttcagc gtatcgatta ttaccagccc ggtgatcaga ctgtgggcca gtttcttgaa aatctcgccc tcgtggctcc ggaccaatgt actagcaaga actgcgaacg tctactactc ttccattacc atttacttgt gcatggtcaa cgtcgcctgc aaattgccgt ggatcagttc ccttgccctt ccccaggaca tgaagaccaa atcatcacat ggtcctattg tcgacagtgt gccactccat cgcccactac gattatgaga gaagagactt ggaagatgtc ttggggagct tacttgcagc agtgctttta tccaccagag attcgagctg gtttctcttg tccccatgac gcatttcgcg atcaaattcg atattacgcc caccgaaacc tggcaattag gatacataat gagcaaatcg atctctttga gcctgtacgg ccatcgatca agctacaggt tagggcggaa actaaggtgg tactcaagaa tagggaatac gacagcgcat tggcgaagat ctatgcattc ttcgattcag tggcatcgcg gctgagaacg attgacgtgg aagatgtgca gtcagataaa gtgtctcgtc ttaatacgac cgttgaatct atgcttgttc gagcggccag cgaccgagaa gagatcacca atctgttgaa caggacgtat aagctcactc cagttacaga tgtgctatca ctgaacgtcg tattgagagc tttacaagac aaagtagtcc aatgggacgt ggactttgca gacattgaga aggctttcat gcccacagag aaagacctga gaaagatgac ggcatcacac ctaaaacgtt tgtttgcaaa tcaggatgcc cctggttcat tagaacggag tgctttaacc ggaacacctt cagtggtttc ggaagagcat gagaccaaag acgatgtcgc actcactcac gtaccgagcg acaagcaaac aactataatc ggtcttagtt ccgatacaaa tacggacgga gcagaagata tcgctacaac gaaattcgat ggtgatgatg cctcaataac acctactgct ggcatacttc aaccaatgtc aaacccgtat tcaagatctg tgagatcggg ttcgaaagag acggacgatg acagtgattc aacggtattt gcgacccacg aggatcttgt aggcaaaagt ggaggcggca aaaccacgat agagccaagc actgagaacg acacttctca gtttgtgtct cgccttcccc gacgcgcagc tcctgctcca agcatagcag accttgttca acgcttcaac gagtctactc agctagctct accgaaactg actcgttccc cggaacgttc acgctctgct ggtggttctt accgccaatc gccccggcaa catccacgac atgacatttc tgacagtgat catagctctc gaaatcgtcc gaagttgcgt cgtggaaaga ctgagcaacc ctctcatcgt caacgggatg cctcgaggcc cggattgatg tctgatggtg atcgaagcta cgctacaaac gcatcacgta tatcatcttc ttcgcacctt catagatcag ttggcgaaag taagaataac gattatctca ctgtcagaca cagtataggc tctcgtgccc cgtcatacac cagcaaggtc tccccgcgtt ccggtagggc ttcgcctaag ttgagatatc cagttgtaac tcatgtccaa tctctcttcg accttgaaga agggaagcct cgcgttgccg gtaaaggtaa atcgcctaga cgtccagagt ctgatacaat cacgccgatt gcgggtaaga atgcaggtcg tcgttctcaa agtggtacct ctcgagtaaa ttccattgca cgtcacttcg atcgtctctc gagagaggcc gaaaaggagc gtcaaaaacg catatccatt gtcagaggca aaagagctag gccagtcagt gtaaccaaag ctaaggtgca ggtgtttgac aatcttaggg acgcgttcag agatgagttc gacaccgatt catcagaggc tgataatgaa gaggatgagc tagggagtga tgacagtctg ggttcagcag acgagctggt ctcaagaacg aaggcagagt cattttcaaa caagtctcct ctcattagac agactggcac ctcgtctgtg ccaatcacca catctccttc cctactgccc ggaccaagct tatcaaacga cgatcttgtc acaacaagtc ctcccattgc gtacgaggcc accacctcta tccttagtga ctccaaatca gaaaagtcct ttacggaccg cttgaagata gaacttccaa gttttgagac cagtgcccct cttccgagtc acccagcgac cccacaagtt cataccgata ccacaacagc agacgaggcc ttgggagcag tttctgcctc acaaacatct gacgtcgaga caagcacggc aaacgagaaa tcaagtttgc taaagtcgct gagtggatta tgggcatttc gggccgccga tttcgctcca ctggaatatc cattatcagc atcggaacac atctttgcag attctaaggt cattatacgt gagactgagc ccaccagcat tatcgcattt actcttagtt cgaagacgta cagagataat tcaaaggcgt ggtcggctag cagacagaaa gagggcagat tcgatacatt catgccagaa gaggccatgg gtactaatca tccagcagca tgggatgctg tttcattgga ggatgtcgat gaggcagcga gacttgaaag aggtacacat atgaaatatg atttcgagtc cggagcttcg accatcttct gcaggatctt tttcgcagag caatttgcag cactacgtaa atcctgcaat tgcgaagata gctttgtgga gtcacttgca cgttgcattc aatttgacgc atctgggggt aaatcagggt cagcgttcct caaaagtcga gacgaccgat tcattgcgaa agagattact cgttacgaga tggacgctct cacgaagttt gcacccgcct actttgacta cactcgcaag gctttccaag gtcagcggcc gacggtcctc gcgaagatat acgggttctt caagatcggc ttcaataacg ccatcactgg caaggctatg aagatgaatg ttctcattat ggaaaatctg ttttatgaac gccgttttgc caagatttat gacttgaaag gtagtactcg taatcggcta atacaaccaa caggacgcat aaacgaggtg ttactggatg agaacttaat ggagatcgtc tataagcatc cgttgtatct ccgtgaacaa tcgaagcgta tattgcgtac tgccctcttc aacgacaccc tttttctttc aaatctcaat gtcatggatt attctttggt cgtgggggtg gacactgata agcatgagct ggtagtgggg attgttgatt atatcaggac ttttacatgg gataagaagc tggaatcgtg ggtaaaagat ttgggggctg gaggaaaagg agagccgacc attgtaactc ccaaacaata taaactgcgt ttccgtactg caatggaacg tttctacttc ccatcggtcc cagaccgttg gaccatagta ggaccggatg aaacccagat agaggaagac gggcctgggg caggcatgac aggttga

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