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Seattle Structural Genomics Center for Infectious Disease

CrneC.19389.a: 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase

Target Characteristics

from organism: Cryptococcus neoformans var. grubii serotype A (H99 / ATCC 208821 / CBS 10515 / FGSC 9487)
most recent status: expressed
center reference id: CrneC.19389.a
is community request: True
associated disease: Pneumonia-like illness
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
unclassified

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
CrneC.19389.a.B4.GE42505 His_phos1 domain 233 432 GE42505
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

External Resources

Resource Reference ID
EuPathDB: FungiDB:CNAG_07372
UniProt: J9VH91

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MAAPLYVTQS GRLWHAGLIL IVTVGLPARG KTHISRALER YLRWLGVKTR VYSIGDYRRK VLGGAKDVPH DYFQTKTPRS EATNALRRRI KAELEDQIMD FFTVQGGQVV IYDANNGSVA ERKSTLEKFG NKGVHVIYLE SLCDQEDIIT ANIRSVKLSS PDYAGWDAEK AVADYWERIR DQTEVYDTVT ADEGPFIKVM NVGERIEVNR IEGYLQTRCC FFLMNIHTRP RNIYFARSGQ SLIEHSYKAD SDLSPAGWEY AERLKAAVIA RRKAAREERK AKGEVLGEEN PLLIWTSARR RAYHTAWPFV HSGYKVVQKP IMSEINPGVW DGLSTQEAME LYPDEWTRFL ADPYAHRAPR AESYHDLSVR LESVIFELER CQDDLLIIGH ASVIRCLLAY LVGLPPNEVP AVEIARGDLV EITPASYGVI SRAWHFWSGE GRGDAYGENL YENFAEATSG KGSVLPDSGV NFAADALNME KEAEEEEGRE KEERGEKVME AAKAVGKIAE QAAANTAAGA GVANSSGDGA GAGGVGQGAR GPGKALKRWG SERGKGRGLP GLSELNETDE GEENKDKDDG GVVSEGEGEG RESGKTRSRA MSLLEI

NT Sequence
atggccgccc cgctctacgt cacgcagtcc ggccgtctgt ggcacgccgg cctcatcctc atcgtcaccg tcggcctccc agcccgcggc aagacacaca tctcccgcgc cctcgaacgc tacctccgct ggctcggcgt caagacccgc gtctactcca tcggcgacta caggcgcaaa gtcctcggcg gcgcaaagga cgtcccccac gactacttcc agacaaagac gcccagatca gaggccacca acgctctccg ccgccgcatc aaggcagaac tcgaagacca gatcatggac tttttcaccg tgcagggcgg ccaggtcgtc atctatgatg ccaacaatgg cagtgtcgca gagagaaaaa gcacgctgga aaagtttggc aacaagggcg tccatgtcat ttatcttgag agtctatgtg accaagaaga tatcatcacc gccaatatcc gcagcgtcaa gctctcgtct cccgactacg ccggatggga cgcagaaaag gcagtcgcag actactggga acgtatccga gaccagactg aagtgtacga caccgtcacg gccgatgaag ggccttttat caaggtgatg aatgtcggcg agaggatcga agtgaaccgt atcgaaggat accttcaaac gcgatgctgc ttcttcttga tgaatatcca cacccgccct cgaaacattt actttgcgcg ttctggacaa tccctcattg aacactcgta taaagccgat tctgacctct ccccggcagg ctgggaatat gctgaacgac tcaaagctgc ggtgatcgcg cggcgcaaag ctgcaagaga agagagaaag gcaaaaggcg aagtcctcgg agaggaaaac cctctgctca tatggacatc cgcgcgccgt cgtgcatacc acaccgcctg gccctttgtc cattccggct acaaggtcgt ccagaaaccc atcatgtcgg aaatcaaccc cggcgtctgg gacggcctct cgacacaaga agccatggaa ctctaccccg acgaatggac ccgtttcctc gccgacccgt atgcgcatcg agcaccccga gcggaaagtt atcatgattt gagtgtgcgg ctcgaaagcg ttattttcga gttggagagg tgtcaggatg atttgttgat tatcggtcat gcttccgtta tccgttgtct cctcgcgtac cttgtcggtc tgcccccgaa cgaagtcccc gcggtcgaaa tcgcgcgggg cgacctcgtc gaaatcacac ccgcctcata cggcgtcatc tcccgcgcat ggcacttttg gtccggtgaa ggccgggggg acgcgtatgg cgaaaacttg tatgaaaact ttgcagaagc gacctctggc aagggttcag tcctgcccga ttcgggggtc aattttgcgg cggatgcgct gaatatggag aaggaggcgg aagaggagga agggagggag aaggaggaga gaggggagaa ggtgatggaa gcggcaaagg cggtggggaa gattgcagag caggctgcgg cgaatacggc agctggtgcc ggtgtggcta acagtagtgg agatggcgca ggcgcaggcg gggtcggtca aggtgcaagg ggaccaggaa aggcgttgaa gagatggggt tcagagaggg ggaaagggag gggtttgccc gggctgagcg agttgaacga gacggatgaa ggggaggaaa acaaggacaa ggatgatggt ggggtagttt cggaaggcga gggtgagggg agagaaagtg gcaagacgag aagtagagct atgagcctct tggaaatcta g

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