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Seattle Structural Genomics Center for Infectious Disease

CrneC.19422.a: AGC/RSK protein kinase (AGC/RSK protein kinase, variant)

Target Characteristics

from organism: Cryptococcus neoformans var. grubii serotype A (H99 / ATCC 208821 / CBS 10515 / FGSC 9487)
most recent status: target approved
center reference id: CrneC.19422.a
is community request: True
associated disease: Pneumonia-like illness
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
unclassified

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

External Resources

Resource Reference ID
EuPathDB: FungiDB:CNAG_04040
UniProt: J9VPC3

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSSLASPPPT ASISTSDSYG SPIQSSGPGL SSGSSTPSKW KSVFKLGRTA TIGKGKENRS ALGGESFVLD NKEQQSFAGG VSPSVVTEPY FPPRGTQLRA HTDPYPPKSR SVKNNLGSAS VEHFDSKVLH EEGMSKTREE GSSESFNIHL NSSNGNLQTT STSGEQSRPY SSVTDSASAS TTERTSHSSG GHFPPADGSS HGMAASNAYG TTSTRSPSGG PLGIGSFKSR FFSAPLSAPA GKNKHDTSKS ERYRGLGKVA TDLPQSTAPP SSAGGASSNG GGRKKSNGSS SFSSRGAASP RTPAKSKREP SANSSKRIPF GQTNENGPNS GSAAARFLRR VVSAPNTKAL FSNNLFSNAP DVPPLPTSKN QPNSSTSSKE KPSSPVVVVG NSEGHIDLTS SPDSYRPPSI SPLSNSSTMY TSQTSHTPPA SASATPTPSP LKQKNHFLSP TASPSPGLGS GLSARGTRAN RSLTTGTAPV LKNIRQLQGY SGLSPGGGGY MDGESRHKQV FRRTYSSNSI KTKQVEVTAS SFQKIKLLGK GDVGKVYLVR EKKTDKLFAM KVLSKKEMIK RNKIKRALAE QEILATANHP FIVTLFHSFQ SQDYLFFVLD YCMGGEFFRA LQTRPGKCLS EEHAKFYAAE VTAALEYLHL NGYIYRDLKP ENILLHQSGH IMLSDFDLSK QSGEAGGAPA AIRHGGPNGQ TILVDTRSCI ADFRTNSFVG TEEYIAPEVI KGHSHSSAVD WWTLGILVYE MIFATTPFKG PNRNATFANV MKNEVLFPET VPVSSNCKSC IRKLLIKDEN KRLGSASGAS EVKQHKWFAS VNWGLLRNMT PPIIPEESNG IDTINFRPLR ESKSIDFDRD DITTDIIHAK AGSPSVSGNA TPGMLTPKEL VQTTSSPSPS GGGAGGVSGH SSSAMPIPGS VRGYDKEKNP FGEFSSVTRD FGEC

NT Sequence
atgtcgtctc tcgcgtcacc tccccctaca gcatccatat ccacctccga ctcttacggc tcccccatcc agtcctcggg cccaggttta agcagcggca gcagtacacc gtcaaagtgg aagagcgtct tcaaactcgg gaggacagcg acaataggga agggtaaaga gaatagatca gcgttgggtg gtgagagctt tgtgctggat aacaaggaac agcagtcatt cgcagggggt gtctcgccct cggtggtaac agaaccttat tttccccctc gtggaacaca gcttcgcgct cataccgacc cttacccgcc taaatcgcgc agtgtcaaaa acaaccttgg tagcgcgagc gttgaacact ttgattctaa agtacttcac gaagaaggca tgtcgaagac gagagaagag ggttcgagtg agagtttcaa tatccatctc aactcgagta atggaaatct ccaaacaaca tcgacctcgg gtgagcagtc gcgaccttac tcgtctgtga cggattctgc gtcggcttct actacagagc gtacttcgca ttcttccggc ggtcatttcc cgccggcaga cgggagttcg cacggtatgg ccgcgtcaaa cgcctacggg accacgtcta ctcgttcacc cagtggcggt ccgcttggga ttgggagctt caaaagccga ttcttttcag ctcccttatc tgcaccagcg ggtaagaaca agcacgatac gagcaagagc gaaaggtatc gtggtctagg caaagtcgct accgatctcc cccagtccac tgcgccacca tccagtgccg gaggagcgtc aagtaatggt ggagggagga agaaaagtaa tggttcatcg tcgttttcgt cgagaggcgc agcgtcgccg cggacgccgg cgaaatcgaa gcgcgagcca tcagccaact cgtctaagcg aataccgttt gggcagacta atgaaaatgg acccaactct ggatcagcag ccgcgaggtt tctccgacgg gtggtctctg ccccaaacac aaaagccctc ttttccaata accttttcag taacgctcct gatgtaccgc cattacctac atccaagaac cagcctaaca gctcaacttc tagcaaggaa aagccctctt cacctgtagt ggttgtcggc aactcggaag gacatatcga cctcacttct tccccggata gctaccgccc gccatcgatc agcccattat ccaactcttc cacaatgtat acctcgcaga catcacatac tcccccagcc tcggcttctg cgactcctac cccctcccct ctcaagcaga agaaccattt tttgagcccg actgcttctc ctagtcccgg tctaggatcg gggctttccg cgagaggaac aagagcgaat agaagcttga cgacgggcac agcgccagtg ctgaaaaata ttagacagct ccagggatat tcggggttaa gtcccggggg aggtgggtat atggatgggg agagcagaca taagcaagta tttaggagga cctatagtag taactctata aagaccaagc aggttgaagt gacggcgtca tcattccaga aaataaaact gctgggtaaa ggagatgttg ggaaagtgta tttggtaagg gagaagaaga cggataagct gtttgctatg aaggtgttat cgaaaaagga aatgatcaaa cgaaacaaga tcaaacgcgc tcttgctgaa caagaaatcc tcgcaacagc aaaccacccc ttcatcgtca ccttgttcca ctcattccaa tcgcaagact acctcttctt cgttctcgac tactgtatgg gcggtgaatt cttccgtgcg ttgcagacga ggccggggaa atgtttgtca gaggagcatg ccaagtttta tgcggcggaa gtgacggcag cgttagaata tcttcatttg aatgggtata tctaccgcga tctgaaacct gagaatatcc tcctccacca gtcgggacat atcatgcttt ctgatttcga cctctcaaag cagtctggtg aagcgggtgg tgccccagca gctatacgtc atggtggacc taacggccaa acaatactgg tagatacacg ttcgtgtata gcggatttca gaaccaattc ctttgtcggt acggaagagt atattgcacc agaagttatc aagggacata gtcattcttc ggctgtggat tggtggacgc tgggtatttt ggtttatgag atgatttttg cgacgacacc attcaagggc ccgaatagga atgcgacgtt tgcgaatgtc atgaagaatg aagtcctctt ccctgaaaca gtacctgttt caagcaattg caaatcatgt attcgcaagc ttttgatcaa agatgagaac aagcgtcttg gttctgcgtc cggtgcaagc gaagtgaagc agcacaagtg gtttgcctcg gtgaactggg gtttgttgcg gaatatgacg ccgcccatta ttcccgagga atcaaatgga attgatacaa taaatttccg acctttgaga gaaagcaaga gcatagattt cgatcgagac gatattacta ccgacatcat ccacgccaaa gcaggttctc cttccgtctc tgggaacgct actcctggta tgctcacccc taaagagctc gtccaaacaa cgtcgtcacc atcaccttcc ggcggtggag cgggcggtgt atcgggccac tcttcgtcag cgatgccaat accaggctcg gtacgcggat atgataagga gaagaatccg tttggggagt ttagcagtgt aacaagagat tttggggagt gctaa

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