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Seattle Structural Genomics Center for Infectious Disease

CrneC.19431.a: AGC/PDK1 protein kinase

Target Characteristics

from organism: Cryptococcus neoformans var. grubii serotype A (H99 / ATCC 208821 / CBS 10515 / FGSC 9487)
most recent status: expressed
center reference id: CrneC.19431.a
is community request: True
associated disease: Pneumonia-like illness
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
unclassified

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
CrneC.19431.a.B2.GE41417 protein kinase domain (short version) 548 811 GE41417
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

External Resources

Resource Reference ID
EuPathDB: FungiDB:CNAG_02915
UniProt: J9VH94

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MASSHFGPAS PASSTPPPSS AYARLIAPTI TRNSSSSSSR STTTCSSTSS VQAVPMRPPP IETSTAATSR SQLPSNRHSE NEAEHDTSYT SPGLSVGGRG GLARNGPRSN RLGTSPQARH VPPSIVALSP SPSPILNMAS KRQSNTETVS GTSPSTPLGK SFLAQQDLSP NSSTIPLRVT ISVDPNDRLS HDRESHSAER PRSSGNSPVR GRHGHLSTPS SPTNSYRALG GKPRTLSVDA GQNWGGSHRS RARDGDDRER RQSQVSSASS GALKKHSLDD WVLGEELGVG SYSTVYCVTP SANTHSPTSP QPARKYALKV INQAHLIQEK KVKYAMVERD ALIRLSDPRP SKGHKRGVSS SSSSGYAQTG SAGKRRSTAS IGGQSSMASV SGGTVSNSKK DTRDRLSIVT TSSAASSPVL TASSGSTQLS PTAVSGGGGN IKGRRPSRSA EPPTPVQEQT EMLIRGGEDG KDGQDGQETP SREWDRDRDW DNMTRSRPPS PVREESAEGG EKEKDEEERS GAEPVELGAA IHLTLPPPQI PSTPEPRGSP LLSTDGHRTS RETPRDRPHL TPKRRRQSLA PSERSVKSAS TTGKMSAAAH PGVVRLYSTF NDSSSLYFVL SLASNGELAS IIRKHGSLDI TSARYYAAQL IDTLEFVHSR GVIHRDLKPE NILLDEDMRI KITDFGSAKI IAKDEPIVDD SSRSRSFVGS ADFVSPEVLR NEVATTASDI WAFGCVLYQF ICGKPPFRGA TDYLTFQKIL KREVEFPKGI DEDAKSLIDT ILDLEPNLRP SITFIKTHPF FQSIDFSTLW TIPAPPISSG LREPSKSTTL AQLEASDIWG VFEGSDVGEE DEDGFEYDAD TVSPRPEGGA VGEGMMEPLF DRRAAASAVH NVDHPKFSRL RNQYINLGED LDPPRPAYAG AGTGGRGKRE KEVEKKKGEK ARGLSHGSES SGGNRSALAG WLEAIKFGGA GGGGMSGSAT SVAASDTVRT PGTGTGTGPG SRPGSRAGIP SFGLGPGSGS RSNRGSGASM RSDEARDLSM SLGGLRMNMS KASEFDKWTP LLLANESIIF TSPITLRTSS PALQLHLPAF LLPAPKKRQL VLTDFPRLLM IKDDNEADGD PAGSDSGAGL SSSSHVESGG GGVGGGGRGG GHGSLRIKGE AVFVPRPSTA TGSSTTKGGG YSAVPNAVMD VQEKGSKGFT VQTPGMVYYC HVDSVELRAK WMAAIHRVGL

NT Sequence
atggcctcct cgcatttcgg ccccgcctcc cccgcctcct ccactccgcc tccttcttcc gcctacgccc gcctcatcgc acccactatc accaggaatt cctcctcctc ctcttcccgc tccaccacaa catgctcctc cacctcctcc gtacaggcag tccccatgcg cccaccaccc atagagacct ctacagcagc cacaagcagg tcacagcttc cgtccaatcg gcacagtgag aacgaggcag agcacgatac gagttacacc agtcccggat tgagtgtcgg aggacgaggc ggattagcca ggaatggccc aagatcaaac agacttggga caagtccaca ggcgaggcat gtgccacctt ccatcgtcgc cttgtcaccg tcaccgtctc caatcctcaa catggcctcc aaaagacagt caaacactga gactgtgtcg ggtacttcgc caagcacacc tctcggcaag tcctttttag cccagcaaga cctctcgcca aatagcagca cgattcctct ccgcgtaacc atctctgttg acccaaatga tcggctttct catgaccgcg aatcccactc tgccgaacgg ccacgctcaa gcggtaactc gcccgtacgc ggccgacatg gccatttgag cacgccttca tcacctacaa actcgtatag ggcgcttggg gggaagccaa ggacacttag tgtggacgct ggacaaaact ggggaggcag tcatcggagt cgagcgagag atggagatga tcgagagcgt cgtcagagcc aggtttcaag cgcgagctct ggagctctca agaaacacag cttggacgac tgggttcttg gtgaggagct cggtgtcgga tcctactcta cagtctactg tgtcacccct tctgccaaca cacactctcc tacttctcct caaccggcga gaaagtatgc cctcaaggtt atcaaccagg cgcatcttat tcaagagaaa aaggtcaagt acgcaatggt agagcgggac gctcttattc gattatctga tcctcgacct tccaagggcc ataagcgagg tgtatcgagc tcttcgagta gtgggtatgc ccagacggga agcgctggga aacgcagatc caccgctagc ataggtggcc agtccagtat ggcttcagtc tctggcggga cggtcagcaa cagcaaaaaa gacacgcgcg atcgcctttc aatcgtaacc acctcgagtg ccgcttccag ccccgtcctt accgcttcga gtggtagcac tcagctctct ccgactgcag taagtggagg tggtggcaat atcaagggta ggcgacctag ccgctcagct gaacctccga caccggtgca ggaacagact gagatgctta ttcgtggtgg agaagatgga aaagatgggc aagatggaca ggagacaccg tcacgagaat gggataggga tagagattgg gataatatga caaggtctcg tcctccctca cctgtaaggg aagagtcagc tgagggcgga gaaaaggaaa aggacgaaga ggagcggtca ggtgcagaac ctgtagagct cggagcagcc atccacctta cgcttcctcc acctcagata ccctctactc ccgaaccacg cggttcgccc cttttgtcaa ccgacggaca tcgtacgagc agagaaaccc cccgagatcg acctcacctg acacctaaac gccggcgtca gtcgttggcc ccgagtgaga gatctgtgaa gagtgcaagt actacaggca aaatgtctgc tgctgcgcac ccgggtgttg tcagattgta ttcgactttt aatgattctt cttcactcta ctttgtactg agccttgcga gtaatggcga gttggcatcc atcattcgca aacatggctc gctcgatatc acttctgcaa ggtactatgc cgctcagttg atcgatactc ttgaattcgt gcattcccga ggtgtcatcc accgtgacct caagccggaa aacattcttc ttgatgagga tatgcgtatc aagattacag atttcggaag tgccaagatc attgccaagg acgagccgat cgtagatgac agttcaagaa gccgatcgtt tgttgggagc gcggactttg tcagtcctga agtcttgcga aacgaagttg caaccactgc atccgacatt tgggcctttg ggtgcgttct ctaccagttt atctgtggaa aacccccttt ccgaggtgcg acagattact tgacctttca aaagatcttg aaacgagaag tggagttccc aaaaggtatt gatgaagatg caaaatctct cattgacacc attcttgacc tcgaacccaa tcttcgacct agcattacat tcatcaaaac ccatccattc ttccagtcta tcgacttttc cacactctgg accatccctg ctcctcccat atccagtggt ctgcgagaac caagcaagtc gacgacgttg gcccagcttg aagcgtcgga tatttggggt gtgtttgaag ggagcgatgt gggtgaggag gatgaggatg ggtttgaata tgatgctgat actgtatcgc cccggccaga gggcggtgcg gttggggagg ggatgatgga acctctgttt gaccggcgcg ccgcggctag cgcagtgcat aatgtcgatc atccgaaatt tagtcgatta cgaaaccaat atatcaacct tggcgaagac ctcgaccctc ctcgacctgc gtatgccggt gctggcacag ggggacgcgg aaaaagggag aaggaagtgg agaagaagaa gggggaaaaa gcgcggggat tgagtcacgg gagtgagagt tcgggtggga accgctcggc gttggcgggg tggttggagg cgatcaagtt tggtggggca gggggaggcg ggatgagtgg aagtgcgaca agcgtggcgg cgagtgacac ggttcgaacg cctggtacgg gtacgggtac ggggcctggc tcgaggcctg gttcgcgtgc tggcatcccg tcgtttggac ttggacctgg cagtggttcg aggtccaaca ggggaagtgg ggcgagtatg aggagcgatg aggcgagaga tttgtcaatg tctcttggtg gactgcggat gaacatgtca aaagcctcag agtttgacaa atggactccc cttcttcttg ccaatgaatc catcattttc acctccccca ttaccctccg tacctcctcc cccgctcttc agctacacct ccccgcattc ttgttaccag cccccaagaa gagacaatta gtcctgaccg atttcccgag gttgttgatg atcaaggacg ataacgaagc ggatggggat ccagcagggt ccgattctgg cgccgggttg tcgtcgtcgt cacatgtcga gtctggtggt ggtggtgttg gtggtggtgg ccgtggtggc gggcatggat cgttgaggat caagggagaa gccgtgtttg ttccccggcc gtcgactgcc accggatctt ccacaacaaa aggtggtggt tactctgccg taccgaacgc ggtgatggat gtgcaggaaa aggggagtaa agggtttact gtccagactc ccgggatggt ttactattgc catgtggata gcgtagagtt gagagcaaag tggatggcgg caattcaccg ggtcgggttg taa

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