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Seattle Structural Genomics Center for Infectious Disease

CrneC.19447.a: AGC protein kinase, variant

Target Characteristics

from organism: Cryptococcus neoformans var. grubii serotype A (H99 / ATCC 208821 / CBS 10515 / FGSC 9487)
most recent status: target approved
center reference id: CrneC.19447.a
is community request: True
associated disease: Pneumonia-like illness
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
unclassified

Ordering Clones & Proteins

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External Resources

Resource Reference ID
EuPathDB: FungiDB:CNAG_03024
UniProt: T2BLV6

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSNGVFFLDE ERERDTLSDP SPTLSPSNPT EDAKSTQPLP SLQVPQTTLA APIPTLGGQP LPQHRKHPAP FAATPSFPSP LARAVTVPSH SDESSSSTHS SPTQSDEEWE GRRNSGQRSP SEMSGSGTPR RWAEGVHESH QRSPSLSRAG SPTSRPPSPT TAGTNTRPQP LTPGALLMRS RRSGSTSRHS PPRIAKKEPT TGQSMPRFVD TFSRVQTGDI SSVHSQSGSS GSGHDQSSPS KSESVSDGRP VAIPSAQDSS KEADSLGLGW GTWESSGSGS SFGSGAGNLR DKGKSRGDLR DIGPPSPRRE RDRTSSVSIS PAKQRRPSEF LNPASEARKM PISNGRPSFS GPGVAHLSTS ASMVSPLNPL PSPWTTASDT SVSAFSPSAS STSESALTSG SSNAGGAIKL NRVPTSVRMA ADLLRNANTA SPVPISGSTP PEHLSPGNEG LVKEQIDQAI MPPPQPPAPS GQYMEDVRPG PTPMTTATPA PSTESHIPLA VGRSPSTPFK TPMVPLLPRP KPSLPRESPA LSSNDNVQTP MESAKVHKYR TSLYEPVKSS NLLSESPSES TSGGENGSPA KSDSASVATS PSRFGLGLSI PSGSSTAPFL SPVPQSTTTE KPGIAQLSRL KGAAGEKRGM AGDLAGINGM GDAASHATMI MQSRQAKIQR WGVGSNRGGF APPPFGRSAS AGSPAMLAAR RADRQSEWGQ LVSGGTAASS PGEDIPATSS LDAFSCAISG TLGPSTSMPS TQTPNPSLLG LSSHGVEDNE LRETAGSSTK HQSNAGAAGV GDIEWVDWMD CYKGYKEMKI KAEAEAMRAK TPKASDNPIF ETKQLGYEHA TRPSLQEERR PAERAHARRF SDQEVTISSQ KSGEKIPMTL TLTPTVSRDS QGGSLHGSMK RQSLSFKNLI AVEPRMSPTQ RRSSFFERQR QSSGSSTKTD HSYVLGSGSG SGTGLMKKKN LVSKMEGWWN AVKSNFVPEH PPGRPGGERT QGRVNRLPKR SGSIPSITQP ESAYLAPEPA ALRGSPNLPL RQVISHNELR QRSQRDDHYE TASVLDSTPA DTARLSRNSS TETAMPIPQH MLVPPPPPVR HASTVTEVTE EPSNPPSRQE PPIHTSLEAR RRQPNLRLEL EPHTLAQPSP HSSNSSSSQP RMVPLGMPLR LSESSLKSSL YGQSLGPGLT PGAPRWDQTP SPVHTFSQHH VEDKEDKPVA PGAELTVGSV RNHIRRRLNG AKEACDASLR RTVNSITKFV EQERQDVGRQ EEVPVDYFET LNLNDSAVFD GEDTGSEAAY ENDGPRSRAV SVSWSRGPSR RPSVSLHAIS PKARTSALAT SPSRIVSRRR PSAVPPRTFG PTGRNVPIPK DRTQSGASSR STSRSHSPMP GRHISLQVDT TDEDRHFLQA LQDLIVLATE VVDSSVHTLK SGLSSCATII QRIQKIGAKW DEHPDWPGRE WYVEILLAVA NLGRVLDWWE AEKGFWNFDA ETENDQLLFV LKPREEQRFD QEFRAALSEP RYSPLSTAVS VAGDLPSALS LDATSPDVPS PQTTKSEEPG KGLSPKALAI DDLKFLAEHA KSVNIVMELS LQGEIVEYVN DAVLEVLGQV PEEVIDHPIT DLLAPGDASV FSEATHQLIE DDNNTVQCRF RFEVHDLAQG ENDERQPGPV YIELEGVGML MRENNEPSHT MWVMKPVAAT QVEAITDAVF PRDGHISTEG ILCRICEREI VAWFFEKHNE TCDALHRLEA EIAECDDCLH ELRQTVVDLE SEVDTAAPNN PAQYQGVLFF TLPESVAGND EKAATQYPQG IEVRKIAHEH LQDVLHILST ARQIETPYVR EEEADLPSSV QNYLSEESED RLLKIMRWQR PQTSEFALNL LFTHVEEQLK RKHKAVARMQ STIRYSEKTR HEWEDKVNEM LAEQEDGSGT ESELGSGGSE VDKSPSEVHA TLPLENPESS PPGPRKIAPL ARLPITQAHP HRQPPALEEL SDPSSTAPTP AAPQMITTEP APPALTSASS EPTVPILAPK VRKAPSQVGS KVHSPDVPPP APSSRVTPSK IGSVKPESRT SSPLLMPYGG DRHHRRRISG SQGMRDAPLS PRIPSAALRS SVAQTTIDDF KILKPISRGA FGSVYLAKKV ATGDYFAIKA LKKSDMISKN QITNVKAERT ILMNQASSPY VAKLFFSFQS KEYLYLVMEY LNGGDCASLV KTLGGLSEDW ARNYTAEVVL GLEYLHKRNI VHRDIKPDNL LIDARGHLKL TDFGLSRIGL LNRQVGGPRP AYLRGISLRG SGQHRLSMTR TMSNSSSIDS NMLSPEITSG QSLPNVSQSY FSQMRPSGPE DESSGSESAG IIPKHVRQMA TKLSSELGTP SVNGKEPPKF VGTPDYLAPE SILGIGQDDA AVDWWALGVV LYEFLYGFPP FHAETPEKVF DNVVSRRIDW HEDEVGISLE ARDLINRLLC SDPQKRLGAN GAEEVKNHPF FAPINWDTIA TSEASFVPDV ADPESTDYFD SRGATVGFHD GDGTLQVSKQ AATDPSAKIN PGAAAMSPNT AGEMEAITND MAEQSDFGAF NYKNLPILKQ ANDDVIRKLR TDSMAPRSQA LEGAPSLSKG KQRRLSVQVQ SKSTRRVSDP NQAPYTPSPS TSTSSAVSTP SRSNMQPPSA STPHHPRRLS ELGALDRVRS SDEADGPRKA QSQARLRGDS GSSVGSNSTE LTKQRRHASL QLDFAASEPS GGLAENKHFV GSNVHSRGLD VLVAEDNPIS QKILETLLTR VGCRCICVDD GPSALAAIMG SIRFDVIICD IHMPVVNGEQ VARMIRSTNN HNQLTPIIAA TSYEQYINEE GTLFSAVLAK PVTKADLIRC LAKLGFVISA GANDVASMPT PAPAVQS

NT Sequence
atgtcgaacg gcgtgttctt tctggatgag gagagagaac gtgacactct tagtgatcct tctccgactc tctcaccatc caatcccaca gaagatgcaa agtctacaca acctcttccg tcccttcaag tacctcaaac cactcttgct gcgcctatcc ctactcttgg agggcagcct ttaccgcaac atcgaaaaca tcctgcgccg tttgcagcga cgccgtcgtt tccttctcca ttggcaagag cagtaacagt gccgtcacat tcagatgaat catcgtcttc tacacattca tcgcctaccc agtctgatga ggaatgggaa ggtcgtcgga atagtggtca gcgttcgccg agtgaaatgt ctggttcggg aacgccgaga cggtgggcgg agggtgtaca tgaatcacac caacggtcgc cgtctttatc ccgtgccggc agccctacct cccgcccacc gagtccgaca acagcaggca cgaatactcg acctcaaccc cttactcccg gtgctttgct catgcgaagt aggcgctcag gaagtacatc ccgacactcc ccaccgcgga ttgcaaagaa agaacccaca acaggtcaga gtatgccgcg gtttgtcgat acctttagtc gcgtgcaaac tggggatatt agttctgtgc attctcaaag cggttccagt ggttctgggc atgaccaatc gagcccttcc aagtcagagt cagtgagcga tggtagacct gtcgctattc catctgccca agattcttca aaggaagcgg attcattggg tctcggttgg ggaacatggg agtcatcagg ttcgggatcg tcctttggaa gtggagcggg taatttgagg gacaaaggaa agtccagagg agacctgagg gatattggac caccgagccc gaggcgagaa agggaccgga cgagtagtgt cagcatcagt ccagcaaagc aaaggcgacc atcagaattc cttaaccctg catcagaagc tcgcaagatg cctatcagca atggccgacc ttctttcagc ggtccgggcg tggcccattt gtcgacatcc gcgtcaatgg tctcacctct caatccttta ccatcgccat ggacaactgc ttctgatact tccgtctctg cattcagtcc ttctgccagt tcgacgagcg aatcagcatt gaccagcggt tcatcaaatg ctggaggagc tatcaagtta aacagagtgc cgacgagcgt aaggatggcg gcggacctgt tgaggaatgc gaatacagct agtccagtcc ccatctccgg tagcacccct cccgaacatc tgtcgccagg aaatgaaggc ctcgtcaaag agcaaatcga tcaggcaatc atgcctccgc ctcaacctcc cgctccttca ggccaatata tggaagatgt tcgacccggt cctacaccga tgacgacggc tacaccggca cctagtactg aatctcatat ccccttggct gttggtcgct ctccgtcgac cccattcaaa acacccatgg tgccactttt acctcgacca aaaccgtcac tacctcgtga atcgccagca ttatcaagta atgataatgt tcaaacgccg atggaatcag caaaggtgca caagtatcgg acttctcttt atgagcctgt taaatcctcg aatttattat ctgagtctcc gtccgaaagc acatctggcg gtgagaatgg ttccccagca aaatcagatt ctgcatcagt cgcaacttct ccctcgcgat tcggtctggg cttgagcata ccttcaggta gcagcacagc gccatttctc tcgcctgtgc cgcagtctac aactaccgaa aaaccaggaa ttgctcaatt gagtcgtttg aaaggtgctg ctggcgagaa gcgtgggatg gctggagatc tggctgggat taacgggatg ggagatgcgg caagtcatgc gacaatgatt atgcagagtc ggcaggcgaa aattcaacga tggggtgtcg gttcgaatag aggaggcttc gctccacccc ccttcggccg ctcagcaagc gctggttccc ctgcaatgct agccgcccgt cgagccgatc gtcaatcaga atggggtcag ctggtcagcg gtggaactgc ggcttcttcg cctggagaag atatcccggc tacaagctca ctcgacgctt tctcatgtgc aatctcaggt acccttggac catcaacatc catgccttcc acccaaactc caaatccttc tttgctcggt ttaagttcac atggcgttga agataacgag ttgagagaaa cagccggatc cagtacgaag caccagtcta acgccggagc agcaggtgtg ggtgacattg agtgggtaga ctggatggac tgttataaag gttacaagga aatgaagatt aaggcagagg cggaagctat gagggcaaag acgccaaagg cgagtgataa tccgattttt gaaacgaagc aactcggata tgaacacgcg acaaggccat cattgcagga ggagaggaga cctgcagaaa gagcccatgc tcgaagattt tcagatcagg aagtgaccat ttcatcacaa aaaagtgggg agaaaattcc aatgacgttg actttgacgc cgacggtatc aagggatagt cagggaggtt cgttacacgg ctccatgaaa aggcaaagct tgtctttcaa aaatcttatt gctgttgagc caaggatgtc gcccacgcaa cggaggtcta gtttctttga gaggcagaga caatcttcag ggagctcaac caagacagat cattcatatg tccttggctc aggttcaggg tctggcacag gtctcatgaa gaagaaaaat ctggtatcga agatggaagg ttggtggaat gctgttaaaa gcaactttgt tcctgagcat cctcctggac gaccgggtgg tgaaagaact caaggaagag tcaaccgttt gccaaagcga agtggcagta taccttccat cacccagccg gaatctgcat atcttgcacc agaaccagca gcccttcgtg gctcccccaa tctaccatta cgtcaagtta tttcacacaa cgagcttcga caacgttcgc agagagacga ccattatgag accgctagtg tcttggactc cactcccgcc gacacggctc gtctttccag aaattcatcc actgaaactg caatgccgat tccgcagcac atgctagtcc ccccgccacc acccgttaga catgcctcta ctgttactga agtaacggag gaaccttcca atccgcccag taggcaggag cccccaattc atacctctct cgaagctcga cgacggcagc ccaacctcag gcttgagctt gagcctcaca ccctcgcaca gcccagtccc catagtagca actcgtctag cagtcagccg cgtatggttc ccctcggtat gcctttacga cttagcgaat cttccttgaa atcctcgctt tatggccaat cgcttggacc aggtttaact cccggcgctc ctagatggga tcaaacaccg tcgcccgtgc atacttttag tcagcatcat gttgaggata aggaggataa gcctgtggcg cccggtgcag aattgactgt gggatctgta cgaaatcata ttcgacgtag attgaacggc gcaaaagaag cttgtgatgc gtcactgagg cgaacggtaa actccataac aaaatttgtt gagcaggaaa gacaagacgt tggtaggcaa gaggaagtgc ctgtggatta ctttgaaacg ttgaatctga atgactctgc ggtttttgat ggggaagaca caggaagtga ggcggcatat gagaacgatg ggccaaggtc acgggcagta tctgtttctt ggtctcgagg tccaagcagg cgtccctctg tctccttgca cgcgattagt cccaaagctc gaacttcagc ccttgctact agccctagcc gaatcgtttc ccgacgaagg ccgagtgcag tgcccccacg aacttttggc cctacaggac gcaacgtccc gataccaaaa gatcgtactc agtctggcgc aagctccaga tcgacttcac gctcacattc acccatgcca gggcgacaca tctccctgca agttgacact acagatgaag atcggcattt cttgcaagcc ttgcaagact tgatcgtgct ggccactgaa gtggttgatt ccagtgttca caccctcaaa tctggtctaa gttcatgtgc caccatcatc cagcgtatcc aaaagatagg tgctaaatgg gatgaacacc ctgactggcc aggacgagaa tggtatgttg agattctcct ggctgttgcc aatctcggcc gtgttttaga ctggtgggag gctgaaaagg gcttctggaa ctttgatgcc gaaaccgaga atgaccagct gttgttcgtg ttgaagccga gagaggaaca aagatttgat caagaattcc gggctgcctt gagtgagcca aggtattcgc ccctgtctac tgctgtatcc gtcgcaggtg acctgccctc ggcgttaagc ctggacgcaa cttcaccaga tgtgcccagt ccacagacta caaagtcaga agaacctggc aagggcttat cacccaaagc tctggctatc gatgatttga agttccttgc tgaacatgct aagagtgtga atattgtgat ggaacttagt ttgcagggtg agatagtaga gtacgtcaac gatgcggtgt tggaggtcct agggcaagtc ccagaagaag tgatagatca tcccattaca gacttgctcg ctcctggtga cgcatcggta ttttccgagg ctacccatca gctcattgag gatgataata acacagttca atgccgattc cgatttgaag ttcatgatct tgcccaaggt gaaaatgatg agcgtcaacc gggcccggta tacatcgagc ttgagggcgt cggcatgttg atgcgtgaga ataatgaacc atcgcacaca atgtgggtga tgaagcccgt tgccgcaact caggtggaag ctatcaccga tgcagtcttc ccgcgcgatg gtcacatctc aacagaggga attctttgtc gaatttgcga aagagaaatc gtcgcttggt tcttcgaaaa gcacaatgaa acctgcgatg ctcttcatcg attggaagct gagattgctg agtgcgatga ttgtttgcac gaacttcgcc agaccgttgt cgatctggaa tctgaagtcg acactgctgc tcccaataat ccggcgcaat atcagggcgt gttgttcttc actctgcccg aatcggttgc aggtaatgat gagaaagccg ccactcaata ccctcaaggg atagaagttc gcaagattgc tcatgaacac ttgcaggatg ttctccatat actaagtacc gcccgccaga tagagacgcc ctacgtgcgc gaggaagaag cagatcttcc atccagtgtc cagaactatc tgtcagaaga gtctgaagat cggctgttga agatcatgag gtggcaacgc cctcagacta gtgaatttgc tcttaacctc ctcttcactc atgtcgaaga acagttgaaa agaaagcaca aggccgtggc gaggatgcag agtaccatca ggtattccga gaagacaaga catgagtggg aagataaggt taatgagatg ttggcggaac aagaggatgg tagcggcacg gagagtgaat tgggttcggg cggcagtgaa gttgataagt ctccctctga ggttcacgca accctcccac tcgaaaatcc agagtcttct ccacccggtc caaggaaaat agctcctttg gccaggttgc ccatcacgca agcacacccc catcgacagc ctccagccct tgaggaatta tcagatccat caagtactgc tcctacccct gcggcccctc aaatgatcac tactgagcct gcgcctccag cactgacgtc cgcttcctcg gagcctacag tccccattct ggcacccaaa gtcaggaaag ctccctctca agtcggatct aaagtgcaca gtccagatgt accacctcct gcgccatcta gccgagtaac gccatctaaa atcggttcag taaaacccga atctaggaca tcttcacctt tattaatgcc atacgggggc gatagacacc atcgtcgtcg catctcaggc tctcaaggaa tgcgcgacgc gcctctttca cctagaatcc cgtccgctgc tctccgatca agcgttgccc aaaccactat tgatgacttt aagatattga agcctatcag tcgaggtgcg tttggctctg tttatctcgc gaaaaaggtt gcaacaggtg attactttgc gatcaaggct ttgaagaagt cagacatgat ttcaaagaat caaatcacca atgtaaaggc tgaacgaaca attttaatga atcaggccag ctcaccgtat gtcgcgaaac ttttcttttc tttccagtcc aaggaatatc tctatcttgt gatggagtat ttaaatggtg gtgattgtgc gtcgttagtc aaaacgttgg gtggtttaag tgaagattgg gcaagaaatt acaccgcaga agtcgtgctg ggtctggagt atctgcataa gaggaatatt gttcatcgag atataaaacc cgataacctc cttattgacg cccgaggtca tttaaagttg accgattttg gtctgtcccg aatcggtttg ttgaatcgtc aggttggtgg tccaaggcct gcataccttc gaggtatttc acttcgaggt tctggtcagc atcgcctgtc aatgactcga acgatgtcga actcgtcatc aattgattca aacatgcttt caccagagat cacctcgggt cagtctttgc caaacgtgtc ccagtcttac ttctcgcaaa tgcgaccatc tgggccggag gatgagtcaa gtggctctga gtctgcggga atcatcccca agcacgtgcg tcaaatggcc actaaacttt cctccgaact tggcactcct tctgtcaatg gcaaagaacc cccaaagttc gttggaacac cagattatct tgcaccagaa agtatactgg gtattggtca agatgatgcg gcagttgatt ggtgggcgtt gggagtagtt ctgtacgagt ttctctacgg cttcccaccc ttccacgcgg agaccccgga gaaggtattc gacaacgtcg tttcaaggag aattgactgg cacgaggatg aggttggcat ctctctcgaa gctcgtgatc tgatcaaccg gcttctatgt tcagaccctc agaagcgact aggagccaac ggtgcagagg aagtcaagaa tcaccctttt ttcgcaccta tcaattggga caccatcgcc acttctgaag caagctttgt gcctgacgtc gctgatcctg aatctaccga ttacttcgac tcccgaggtg cgactgtagg cttccatgat ggtgacggca cattacaagt atcgaagcag gcagcaactg accccagtgc aaagataaac cctggtgccg ccgctatgtc tccaaatacg gcaggcgaaa tggaagccat caccaatgac atggccgaac aaagtgattt tggcgccttc aactataaaa atctaccaat tttgaagcaa gccaacgacg atgtcattcg aaagttgagg acagattcta tggctcctcg cagccaagca ttagagggtg ctccttccct gagcaaagga aaacaaagaa gattatccgt acaggtgcag agcaagtcta cccgaagggt atctgatccc aatcaggctc catacactcc ttctccttca acatccacat cctcggctgt ctccactcca tcccgaagca acatgcagcc accttctgct tcgactccac accaccccag gcgtttgtcc gagcttggtg ctctcgaccg agtcagatcg agtgatgagg cggacggacc acgaaaggct cagtcacagg ctcgattgcg aggtgattca gggtcaagcg tcggtagcaa tagcacagaa ttgacaaaac agcgccgcca tgcctccttg caactagatt tcgctgcctc agagccttct gggggtttag cagaaaataa gcattttgtg gggtcgaacg tccatagcag aggattggat gtgttggttg cagaggataa tcctatatca caaaaaattc ttgaaactct gcttactcga gtgggatgtc gatgtatctg tgtggatgat ggaccctcag ctttggcggc gattatgggc agcatacgat tcgatgtcat tatctgtgat attcatatgc cggtcgtaaa tggagagcaa gttgctcgaa tgatcaggtc gaccaacaat cataaccagc ttacaccaat cattgctgca acttcgtatg agcaatatat caatgaggag gggaccttat tctctgcagt attggccaag cctgtcacga aggcagacct catcagatgt ttggccaagc tcgggtttgt aatcagtgcc ggtgccaatg atgtcgcgtc aatgccgaca ccggctcctg cggttcaatc gtaa

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