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Seattle Structural Genomics Center for Infectious Disease

DecoA.18655.a: Spike protein

Target Characteristics

from organism: Deltacoronavirus Coronavirus HKU15 PDCoV/USA/Illinois121/2014
most recent status: in PDB
center reference id: DecoA.18655.a
is community request: False
associated disease:
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
unclassified

Ordering Clones & Proteins

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Structures

image of structure for 6BFU
6BFU
Deposited: 10/27/2017
Determination: CryoEM
Clone: DecoA.18655.a.LC21.GE42189
Protein: DecoA.18655.a.LC21.PE00001

Publications by SSGCID

Glycan shield and fusion activation of a deltacoronavirus spike glycoprotein fine-tuned for enteric infections
Tortorici MA, Snijder J, Yoshioka C, Walls AC, McGuire AT, Rey FA, Bosch BJ, Veesler D, Xiong X, Li W
J. Virol. - 2017
volume 92, issue 4, pages e01628-17
PMID: 29093093 ; PMCID: PMC5790929
PDB: 6BFU

Citations by Others

Unraveling virus relationships by structure-based phylogenetic classification
WM Ng, AJ Stelfox, TA Bowden- Virus Evolution, 2020 - academic.oup.com
PDB: 6BFU
Structure and immune recognition of the porcine epidemic diarrhea virus spike protein
RN Kirchdoerfer, M Bhandari, O Martini, LM Sewall- bioRxiv, 2020 - biorxiv.org
PDB: 6BFU
Glycosylator: a Python framework for the rapid modeling of glycans
T Lemmin, C Soto- BMC bioinformatics, 2019 - Springer
PDB: 6BFU
Glycosylation of viral surface proteins probed by mass spectrometry
AA Hargett, MB Renfrow- Current opinion in virology, 2019 - Elsevier
PDB: 6BFU
Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis
RN Kirchdoerfer, N Wang, J Pallesen, D Wrapp- Scientific reports, 2018 - nature.com
cited by: 7 others
PDB: 6BFU

This list was obtained from Google Scholar searches using the Open Source tool https://github.com/ckreibich/scholar.py and each citation has been manually reviewed.

External Resources

Resource Reference ID
UniProt: W8Q9Y7
ViPR: link

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MQRALLIMTL LCLVRAKFAD DLLDLLTFPG AHRFLHKPTR NSSSLYSRAN NNFDVGVLPG YPTKNVNLFS PLTNSTLPIN GLHRSYQPLM LNCLTKITNH TLSMYLLPSE IQTYSCGGAM VKYQTHDAVR IILDLTATDH ISVEVVGQHG ENYVFVCSEQ FNYTTALHNS TFFSLNSELY CFTNNTYLGI LPPDLTDFTV YRTGQFYANG YLLGTLPITV NYVRLYRGHL SANSAHFALA NLTDTLITLT NTTISQITYC DKSVVDSIAC QRSSHEVEDG FYSDPKSAVR ARQRTIVTLP KLPELEVVQL NISAHMDFGE ARLDSVTING NTSYCVTKPY FRLETNFMCT GCTMNLRTDT CSFDLSAVNN GMSFSQFCLS TESGACEMKI IVTYVWNYLL RQRLYVTAVE GQTHTGTTSV HATDTSSVIT DVCTDYTIYG VSGTGIIKPS DLLLHNGIAF TSPTGELYAF KNITTGKTLQ VLPCETPSQL IVINNTVVGA ITSSNSTENN RFTTTIVTPT FFYSTNATTF NCTKPVLSYG PISVCSDGAI VGTSTLQNTR PSIVSLYDGE VEIPSAFSLS VQTEYLQVQA EQVIVDCPQY VCNGNSRCLQ LLAQYTSACS NIEAALHSSA QLDSREIINM FQTSTQSLQL ANITNFKGDY NFSSILTTRI GGRSAIEDLL FNKVVTSGLG TVDQDYKSCS RDMAIADLVC SQYYNGIMVL PGVVDAEKMA MYTGSLTGAM VFGGLTAAAA IPFATAVQAR LNYVALQTNV LQENQKILAE SFNQAVGNIS LALSSVNDAI QQTSEALNTV AIAIKKIQTV VNQQGEALSH LTAQLSNNFQ AISTSIQDIY NRLEEVEANQ QVDRLITGRL AALNAYVTQL LNQMSQIRQS RLLAQQKINE CVKSQSPRYG FCGNGTHIFS LTQTAPNGIF FMHAVLVPNK FTRVNASAGI CVDNTRGYSL QPQLILYQFN NSWRVTPRNM YEPRLPRQAD FIQLTDCSVT FYNTTAANLP NIIPDIIDVN QTVSDIIDNL PTATPPQWDV GIYNNTILNL TVEINDLQER SKNLSQIADR LQNYIDNLNN TLVDLEWLNR VETYLKWPWY IWLAIALALI AFVTILITIF LCTGCCGGCF GCCGGCFGLF SKKKRYTDDQ PTPSFKFKEW

NT Sequence
ATGCAGAGAG CTCTATTGAT TATGACCTTA CTTTGTCTCG TTCGAGCAAA GTTTGCTGAT GATCTACTCG ATTTGCTCAC CTTCCCGGGT GCACATCGCT TCTTACATAA ACCCACGAGG AATTCCAGCA GTCTCTACTC GCGGGCTAAT AATAATTTTG ATGTTGGCGT TCTTCCTGGC TACCCCACTA AGAACGTTAA CCTCTTCTCA CCACTTACTA ACTCCACTTT GCCCATTAAT GGCCTTCATC GGAGTTACCA ACCACTCATG CTGAATTGTC TTACTAAAAT AACTAACCAC ACTCTCAGCA TGTATCTCCT ACCTAGTGAG ATACAAACTT ATAGCTGCGG CGGTGCCATG GTTAAATACC AGACACATGA TGCAGTTCGT ATCATTTTAG ACCTCACTGC CACTGACCAC ATCTCTGTTG AAGTCGTTGG CCAACATGGT GAAAATTATG TGTTTGTTTG CAGTGAGCAG TTTAACTACA CCACTGCATT ACACAACTCT ACCTTCTTCT CACTTAATTC TGAGCTTTAT TGCTTTACTA ATAACACCTA CTTAGGTATT CTTCCACCTG ATTTAACTGA CTTTACGGTC TACCGTACTG GTCAGTTCTA TGCTAATGGT TACCTTTTAG GTACTTTACC TATTACGGTT AACTATGTTA GGTTGTATCG GGGTCATTTG TCTGCCAATA GTGCCCACTT TGCCCTTGCA AACCTAACCG ATACACTCAT AACACTTACC AATACTACTA TATCGCAAAT CACTTATTGT GATAAGTCAG TAGTTGATTC AATAGCATGC CAGCGCTCTT CTCACGAAGT GGAGGATGGG TTTTACTCCG ACCCTAAATC TGCCGTTAGA GCTAGGCAAC GTACTATTGT TACACTACCT AAGCTCCCTG AGCTTGAAGT AGTGCAGTTA AATATTTCTG CACACATGGA TTTTGGCGAA GCCAGACTTG ACAGCGTTAC CATCAATGGT AACACATCCT ATTGTGTCAC TAAGCCTTAC TTCAGGCTTG AAACTAACTT TATGTGTACA GGTTGCACTA TGAATCTGCG CACTGATACC TGTAGTTTTG ACCTGTCAGC AGTAAACAAT GGCATGTCAT TCTCTCAATT CTGTCTAAGC ACTGAATCTG GTGCTTGTGA GATGAAAATT ATTGTTACCT ACGTATGGAA TTACTTGCTA AGGCAGCGTT TGTATGTTAC TGCTGTAGAG GGCCAGACTC ACACTGGAAC CACTTCAGTA CATGCAACAG ACACTTCTAG TGTAATCACT GATGTCTGCA CTGACTACAC TATCTATGGA GTCTCTGGTA CTGGCATTAT TAAGCCATCA GATCTCTTAT TGCACAATGG CATAGCATTC ACCTCTCCAA CAGGTGAGCT TTATGCATTT AAAAATATAA CCACTGGCAA AACCCTTCAG GTCTTACCGT GTGAAACCCC TTCTCAACTG ATTGTGATAA ACAACACCGT TGTCGGTGCT ATCACATCCA GTAATTCAAC TGAAAATAAT AGGTTTACTA CTACTATTGT CACACCTACT TTCTTTTATT CCACAAATGC CACCACTTTC AACTGCACTA AGCCTGTTTT GTCCTATGGA CCTATCAGCG TGTGTAGTGA TGGTGCAATT GTGGGAACAT CCACATTACA GAATACTCGA CCATCCATAG TTTCACTATA CGATGGCGAA GTTGAAATAC CATCTGCATT TTCTCTTTCC GTTCAGACGG AGTACTTGCA AGTTCAAGCA GAGCAAGTTA TAGTTGATTG TCCTCAGTAT GTATGCAATG GCAACAGCCG TTGTCTACAA TTACTGGCAC AATACACCTC AGCTTGCTCT AACATTGAAG CAGCTCTGCA TTCCTCTGCA CAGTTGGATA GCAGAGAGAT TATAAATATG TTTCAAACAT CAACACAGTC CTTGCAGTTA GCTAATATTA CCAACTTCAA GGGTGACTAC AATTTTAGCA GCATACTAAC CACCAGAATT GGTGGCAGAT CTGCTATTGA AGACCTTCTT TTTAATAAAG TTGTTACTAG TGGCCTTGGC ACTGTTGATC AGGACTACAA ATCCTGCTCT AGAGACATGG CCATCGCTGA CTTAGTTTGT TCCCAGTATT ACAATGGCAT CATGGTTCTA CCTGGTGTTG TTGATGCTGA GAAAATGGCA ATGTATACTG GCTCTCTTAC TGGAGCTATG GTATTTGGAG GACTGACTGC CGCAGCGGCA ATACCATTTG CCACGGCAGT ACAAGCTCGC CTCAATTATG TCGCACTGCA AACAAATGTA CTACAAGAAA ACCAGAAAAT TCTTGCAGAA TCATTTAACC AAGCAGTTGG CAATATATCA CTTGCACTAT CTTCTGTTAA TGATGCCATC CAGCAAACTT CTGAGGCTCT TAACACCGTA GCTATTGCTA TTAAAAAGAT TCAAACAGTT GTTAACCAGC AGGGCGAGGC ATTATCACAC CTGACTGCAC AGCTGTCAAA CAATTTTCAA GCAATTTCGA CTTCTATTCA AGACATTTAC AACCGTCTTG AGGAAGTAGA GGCTAACCAG CAAGTTGACC GTCTCATCAC AGGACGGTTG GCTGCACTTA ATGCATATGT TACTCAGTTA CTCAATCAGA TGTCTCAGAT TAGACAATCT CGATTGTTAG CTCAGCAAAA GATTAATGAG TGTGTCAAAT CACAGTCGCC AAGATACGGT TTCTGTGGAA ATGGCACACA CATCTTCTCA CTTACACAGA CTGCACCAAA TGGCATATTT TTCATGCATG CAGTGCTAGT ACCCAACAAA TTCACACGTG TCAACGCTTC TGCCGGCATT TGTGTGGATA ATACGAGAGG CTACTCATTG CAGCCTCAAC TTATACTCTA CCAGTTTAAT AACTCCTGGA GAGTTACACC TAGAAATATG TATGAACCCA GACTGCCCCG GCAGGCTGAT TTCATACAAT TAACTGATTG CAGCGTTACT TTTTACAACA CCACCGCTGC TAATCTTCCC AATATTATCC CTGACATTAT AGATGTCAAT CAAACAGTCA GTGATATTAT TGACAATTTA CCTACAGCAA CACCTCCTCA GTGGGATGTT GGTATCTATA ACAACACTAT TCTCAACCTC ACCGTTGAGA TTAATGATCT ACAAGAGCGG TCTAAAAACC TCTCACAGAT TGCAGATCGT TTACAAAATT ATATTGACAA TCTTAACAAT ACTCTAGTTG ACCTTGAATG GCTCAACAGA GTGGAAACTT ACCTTAAATG GCCGTGGTAT ATATGGCTTG CCATTGCCCT GGCTCTTATT GCATTTGTGA CAATCCTCAT AACAATCTTT CTTTGTACTG GTTGTTGTGG TGGTTGCTTT GGTTGTTGTG GCGGTTGTTT TGGCCTTTTC TCTAAGAAGA AAAGGTATAC TGACGACCAA CCAACACCGT CCTTTAAGTT TAAGGAATGG

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