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Seattle Structural Genomics Center for Infectious Disease

HosaA.19747.a: Cadherin-1; E-cadherin

Target Characteristics

from organism: Homo sapiens
most recent status: in PDB
center reference id: HosaA.19747.a
is community request: True
associated disease:
NIH risk group: unclassified
is select agent: False
NIH priority
pathogens category:
unclassified

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Structures

image of structure for 6CXY
6CXY
Deposited: 4/4/2018
Determination: XRay
Diffraction Image
Clone: HosaA.19747.a.KW2.GE41924
Protein: HosaA.19747.a.KW2.PC00156
image of structure for 6VEL
6VEL
Deposited: 1/2/2020
Determination: XRay
Diffraction Image
Clone: HosaA.19747.a.KW2.GE41924
Protein: HosaA.19747.a.KW2.PC00161

External Resources

Resource Reference ID
UniProt: P12830

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MGPWSRSLSA LLLLLQVSSW LCQEPEPCHP GFDAESYTFT VPRRHLERGR VLGRVNFEDC TGRQRTAYFS LDTRFKVGTD GVITVKRPLR FHNPQIHFLV YAWDSTYRKF STKVTLNTVG HHHRPPPHQA SVSGIQAELL TFPNSSPGLR RQKRDWVIPP ISCPENEKGP FPKNLVQIKS NKDKEGKVFY SITGQGADTP PVGVFIIERE TGWLKVTEPL DRERIATYTL FSHAVSSNGN AVEDPMEILI TVTDQNDNKP EFTQEVFKGS VMEGALPGTS VMEVTATDAD DDVNTYNAAI AYTILSQDPE LPDKNMFTIN RNTGVISVVT TGLDRESFPT YTLVVQAADL QGEGLSTTAT AVITVTDTND NPPIFNPTTY KGQVPENEAN VVITTLKVTD ADAPNTPAWE AVYTILNDDG GQFVVTTNPV NNDGILKTAK GLDFEAKQQY ILHVAVTNVV PFEVSLTTST ATVTVDVLDV NEAPIFVPPE KRVEVSEDFG VGQEITSYTA QEPDTFMEQK ITYRIWRDTA NWLEINPDTG AISTRAELDR EDFEHVKNST YTALIIATDN GSPVATGTGT LLLILSDVND NAPIPEPRTI FFCERNPKPQ VINIIDADLP PNTSPFTAEL THGASANWTI QYNDPTQESI ILKPKMALEV GDYKINLKLM DNQNKDQVTT LEVSVCDCEG AAGVCRKAQP VEAGLQIPAI LGILGGILAL LILILLLLLF LRRRAVVKEP LLPPEDDTRD NVYYYDEEGG GEEDQDFDLS QLHRGLDARP EVTRNDVAPT LMSVPRYLPR PANPDEIGNF IDENLKAADT DPTAPPYDSL LVFDYEGSGS EAASLSSLNS SESDKDQDYD YLNEWGNRFK KLADMYGGGE DD

NT Sequence
atgggccctt ggagccgcag cctctcggcg ctgctgctgc tgctgcaggt ctcctcttgg ctctgccagg agccggagcc ctgccaccct ggctttgacg ccgagagcta cacgttcacg gtgccccggc gccacctgga gagaggccgc gtcctgggca gagtgaattt tgaagattgc accggtcgac aaaggacagc ctatttttcc ctcgacaccc gattcaaagt gggcacagat ggtgtgatta cagtcaaaag gcctctacgg tttcataacc cacagatcca tttcttggtc tacgcctggg actccaccta cagaaagttt tccaccaaag tcacgctgaa tacagtgggg caccaccacc gccccccgcc ccatcaggcc tccgtttctg gaatccaagc agaattgctc acatttccca actcctctcc tggcctcaga agacagaaga gagactgggt tattcctccc atcagctgcc cagaaaatga aaaaggccca tttcctaaaa acctggttca gatcaaatcc aacaaagaca aagaaggcaa ggttttctac agcatcactg gccaaggagc tgacacaccc cctgttggtg tctttattat tgaaagagaa acaggatggc tgaaggtgac agagcctctg gatagagaac gcattgccac atacactctc ttctctcacg ctgtgtcatc caacgggaat gcagttgagg atccaatgga gattttgatc acggtaaccg atcagaatga caacaagccc gaattcaccc aggaggtctt taaggggtct gtcatggaag gtgctcttcc aggaacctct gtgatggagg tcacagccac agacgcggac gatgatgtga acacctacaa tgccgccatc gcttacacca tcctcagcca agatcctgag ctccctgaca aaaatatgtt caccattaac aggaacacag gagtcatcag tgtggtcacc actgggctgg accgagagag tttccctacg tataccctgg tggttcaagc tgctgacctt caaggtgagg ggttaagcac aacagcaaca gctgtgatca cagtcactga caccaacgat aatcctccga tcttcaatcc caccacgtac aagggtcagg tgcctgagaa cgaggctaac gtcgtaatca ccacactgaa agtgactgat gctgatgccc ccaatacccc agcgtgggag gctgtataca ccatattgaa tgatgatggt ggacaatttg tcgtcaccac aaatccagtg aacaacgatg gcattttgaa aacagcaaag ggcttggatt ttgaggccaa gcagcagtac attctacacg tagcagtgac gaatgtggta ccttttgagg tctctctcac cacctccaca gccaccgtca ccgtggatgt gctggatgtg aatgaagccc ccatctttgt gcctcctgaa aagagagtgg aagtgtccga ggactttggc gtgggccagg aaatcacatc ctacactgcc caggagccag acacatttat ggaacagaaa ataacatatc ggatttggag agacactgcc aactggctgg agattaatcc ggacactggt gccatttcca ctcgggctga gctggacagg gaggattttg agcacgtgaa gaacagcacg tacacagccc taatcatagc tacagacaat ggttctccag ttgctactgg aacagggaca cttctgctga tcctgtctga tgtgaatgac aacgccccca taccagaacc tcgaactata ttcttctgtg agaggaatcc aaagcctcag gtcataaaca tcattgatgc agaccttcct cccaatacat ctcccttcac agcagaacta acacacgggg cgagtgccaa ctggaccatt cagtacaacg acccaaccca agaatctatc attttgaagc caaagatggc cttagaggtg ggtgactaca aaatcaatct caagctcatg gataaccaga ataaagacca agtgaccacc ttagaggtca gcgtgtgtga ctgtgaaggg gccgccggcg tctgtaggaa ggcacagcct gtcgaagcag gattgcaaat tcctgccatt ctggggattc ttggaggaat tcttgctttg ctaattctga ttctgctgct cttgctgttt cttcggagga gagcggtggt caaagagccc ttactgcccc cagaggatga cacccgggac aacgtttatt actatgatga agaaggaggc ggagaagagg accaggactt tgacttgagc cagctgcaca ggggcctgga cgctcggcct gaagtgactc gtaacgacgt tgcaccaacc ctcatgagtg tcccccggta tcttccccgc cctgccaatc ccgatgaaat tggaaatttt attgatgaaa atctgaaagc ggctgatact gaccccacag ccccgcctta tgattctctg ctcgtgtttg actatgaagg aagcggttcc gaagctgcta gtctgagctc cctgaactcc tcagagtcag acaaagacca ggactatgac tacttgaacg aatggggcaa tcgcttcaag aagctggctg acatgtacgg aggcggcgag gacgactag

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